Search Results - Alvin W. Nienow

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  1. 1
    The scale-up of microbial batch and fed-batch fermentation processes

    The scale-up of microbial batch and fed-batch fermentation processes by Christopher Hewitt, Alvin W. Nienow

    Published 2010
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  2. 2
    Studies supporting the use of mechanical mixing in large scale beer fermentations

    Studies supporting the use of mechanical mixing in large scale beer fermentations by Alvin W. Nienow, Georgina McLeod, Christopher Hewitt

    Published 2010
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  3. 3
    A quantitative approach for understanding small-scale human mesenchymal stem cell culture implications for large-scale bioprocess development

    A quantitative approach for understanding small-scale human mesenchymal stem cell culture implications for large-scale bioprocess development by Qasim Rafiq, Karen Coopman, Alvin W. Nienow, Christopher Hewitt

    Published 2013
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  4. 4
    A potentially scalable method for the harvesting of hMSCs from microcarriers

    A potentially scalable method for the harvesting of hMSCs from microcarriers by Alvin W. Nienow, Qasim Rafiq, Karen Coopman, Christopher Hewitt

    Published 2014
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  5. 5
    Large-scale expansion and exploitation of pluripotent stem cells for regenerative medicine purposes: beyond the T flask

    Large-scale expansion and exploitation of pluripotent stem cells for regenerative medicine purposes: beyond the T flask by Andrew Want, Alvin W. Nienow, Christopher Hewitt, Karen Coopman

    Published 2012
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  6. 6
    A liquid/liquid two phase system as an economic alternative for the large-scale expansion of bone marrow-derived human mesenchymal stem/stromal cells (hMSCs)

    A liquid/liquid two phase system as an economic alternative for the large-scale expansion of bone marrow-derived human mesenchymal stem/stromal cells (hMSCs) by Mariana P. Hanga, Alvin W. Nienow, Karen Coopman, Christopher J. Hewitt

    Published 2017
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  7. 7
    Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors

    Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors by Qasim A. Rafiq, Karen Coopman, Alvin W. Nienow, Christopher J. Hewitt

    Published 2016
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  8. 8
    The role of biopreservation in cell and gene therapy bioprocessing

    The role of biopreservation in cell and gene therapy bioprocessing by Qasim A. Rafiq, Alvin W. Nienow, Christopher J. Hewitt, Karen Coopman

    Published 2017
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  9. 9
    Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor

    Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor by Qasim Rafiq, Kathryn Brosnan, Karen Coopman, Alvin W. Nienow, Christopher Hewitt

    Published 2013
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  10. 10
    Expansion of human mesenchymal stem cells on microcarriers

    Expansion of human mesenchymal stem cells on microcarriers by Christopher Hewitt, Kenneth Lee, Alvin W. Nienow, Rob Thomas, M. Smith, Colin R. Thomas

    Published 2011
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  11. 11
    Mixing theory for culture and harvest in bioreactors of human mesenchymal stem cells on microcarriers

    Mixing theory for culture and harvest in bioreactors of human mesenchymal stem cells on microcarriers by Alvin W. Nienow, Qasim A. Rafiq, Thomas R.J. Heathman, Karen Coopman, Christopher J. Hewitt

    Published 2016
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  12. 12
    The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

    The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4 by Alvin W. Nienow, Chris Rielly, Kathryn Brosnan, Neil Bargh, Kenneth Lee, Karen Coopman, Christopher Hewitt

    Published 2013
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  13. 13
    Engineering considerations on the use of liquid/liquid two phase systems as a cell culture platform

    Engineering considerations on the use of liquid/liquid two phase systems as a cell culture platform by Halina Murasiewicz, Alvin W. Nienow, Mariana P. Hanga, Karen Coopman, Christopher J. Hewitt, Andrzej W. Pacek

    Published 2016
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  14. 14
    Expansion of bone marrow‐derived human mesenchymal stem/stromal cells (hMSCs) using a two‐phase liquid/liquid system

    Expansion of bone marrow‐derived human mesenchymal stem/stromal cells (hMSCs) using a two‐phase liquid/liquid system by Mariana P. Hanga, Halina Murasiewicz, Andrzej W. Pacek, Alvin W. Nienow, Karen Coopman, Christopher J. Hewitt

    Published 2017
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  15. 15
    Development of a process control strategy for the serum-free microcarrier expansion of human mesenchymal stem cells towards cost-effective and commercially viable manufacturing

    Development of a process control strategy for the serum-free microcarrier expansion of human mesenchymal stem cells towards cost-effective and commercially viable manufacturing by Thomas R.J. Heathman, Alvin W. Nienow, Qasim A. Rafiq, Karen Coopman, Bo Kara, Christopher J. Hewitt

    Published 2018
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  16. 16
    Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development

    Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development by Thomas R.J. Heathman, Alvin W. Nienow, Qasim A. Rafiq, Karen Coopman, Bo Kara, Christopher J. Hewitt

    Published 2018
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  17. 17
    Characterisation of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development

    Characterisation of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development by Thomas Heathman, Qasim A. Rafiq, Alex Chan, Karen Coopman, Alvin W. Nienow, Bo Kara, Christopher J. Hewitt

    Published 2016
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  18. 18
    The translation of cell-based therapies: clinical landscape and manufacturing challenges

    The translation of cell-based therapies: clinical landscape and manufacturing challenges by Thomas R.J. Heathman, Alvin W. Nienow, Mark McCall, Karen Coopman, Bo Kara, Christopher J. Hewitt

    Published 2015
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  19. 19
    Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate

    Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate by Thomas Heathman, Alexandra Stolzing, Claire Fabian, Qasim A. Rafiq, Karen Coopman, Alvin W. Nienow, Bo Kara, Christopher J. Hewitt

    Published 2016
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  20. 20
    Serum-free process development: improving the yield and consistency of human mesenchymal stem cell production

    Serum-free process development: improving the yield and consistency of human mesenchymal stem cell production by Thomas Heathman, Alexandra Stolzing, Claire Fabian, Qasim A. Rafiq, Alvin W. Nienow, Karen Coopman, Bo Kara, Christopher J. Hewitt

    Published 2015
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  21. 21
    Scale-down studies for assessing the impact of different stress parameters on growth and product quality during animal cell culture

    Scale-down studies for assessing the impact of different stress parameters on growth and product quality during animal cell culture by Alvin W. Nienow, William H. Scott, Christopher Hewitt, Colin R. Thomas, Gareth Lewis, Ashraf Amanullah, Robert Kiss, Steven J. Meier

    Published 2013
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  22. 22
    Process development of human multipotent stromal cell microcarrier culture using an automated high-throughput microbioreactor

    Process development of human multipotent stromal cell microcarrier culture using an automated high-throughput microbioreactor by Qasim A. Rafiq, Mariana P. Hanga, Thomas R.J. Heathman, Karen Coopman, Alvin W. Nienow, David Williams, Christopher J. Hewitt

    Published 2017
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  23. 23
    Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum-free microcarrier process

    Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum-free microcarrier process by Thomas Heathman, Veronica A.M. Glyn, Andy Picken, Qasim A. Rafiq, Karen Coopman, Alvin W. Nienow, Bo Kara, Christopher J. Hewitt

    Published 2015
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  24. 24
    Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms

    Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms by Alvin W. Nienow, Christopher J. Hewitt, Thomas Heathman, Veronica A.M. Glyn, G. Fonte, Petra Hanga, Karen Coopman, Qasim A. Rafiq

    Published 2016
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  25. 25
    Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: utilising the phenomenon to improve culture performance

    Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: utilising the phenomenon to improve cult... by Qasim A. Rafiq, Steven Ruck, Mariana P. Hanga, Thomas R.J. Heathman, Karen Coopman, Alvin W. Nienow, David Williams, Christopher J. Hewitt

    Published 2017
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