Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer by Ricciuti, Biagio, Kravets, Sasha, Dahlberg, Suzanne E, Umeton, Renato, Albayrak, Adem, Subegdjo, Safiya J, Johnson, Bruce E, Nishino, Mizuki, Sholl, Lynette M, Awad, Mark M

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Somatic mutations in CDH1 and CTNNB1 in primary carcinomas at 13 anatomic sites by Busch, Evan L, Hornick, Jason L, Umeton, Renato, Albayrak, Adem, Lindeman, Neal I, MacConaill, Laura E, Garcia, Elizabeth P, Ducar, Matthew, Rebbeck, Timothy R

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MatchMiner: an open-source platform for cancer precision medicine by Klein, Harry, Mazor, Tali, Siegel, Ethan, Trukhanov, Pavel, Ovalle, Andrea, Vecchio Fitz, Catherine Del, Zwiesler, Zachary, Kumari, Priti, Van Der Veen, Bernd, Marriott, Eric, Hansel, Jason, Yu, Joyce, Albayrak, Adem, Barry, Susan, Keller, Rachel B., MacConaill, Laura E., Lindeman, Neal, Johnson, Bruce E., Rollins, Barrett J., Do, Khanh T., Beardslee, Brian, Shapiro, Geoffrey, Hector-Barry, Suzanne, Methot, John, Sholl, Lynette, Lindsay, James, Hassett, Michael J., Cerami, Ethan

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Molecular Mechanisms of Acquired Resistance to MET Tyrosine Kinase Inhibitors in Patients with MET Exon 14-Mutant NSCLC by Recondo, Gonzalo, Bahcall, Magda, Spurr, Liam F, Che, Jianwei, Ricciuti, Biagio, Leonardi, Giulia C, Lo, Ying-Chun, Li, Yvonne Y, Lamberti, Giuseppe, Nguyen, Tom, Milan, Marina S D, Venkatraman, Deepti, Umeton, Renato, Paweletz, Cloud P, Albayrak, Adem, Cherniack, Andrew D, Price, Kristin S, Fairclough, Stephen R, Nishino, Mizuki, Sholl, Lynette M, Oxnard, Geoffrey R, Jänne, Pasi A, Awad, Mark M

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Evolving phenotypes of non-hospitalized patients that indicate long COVID by Estiri, Hossein, Strasser, Zachary H, Brat, Gabriel A, Semenov, Yevgeniy R, Patel, Chirag J, Murphy, Shawn N

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What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask by Kohane, Isaac S, Aronow, Bruce J, Avillach, Paul, Beaulieu-Jones, Brett K, Bellazzi, Riccardo, Bradford, Robert L, Brat, Gabriel A, Cannataro, Mario, Cimino, James J, García-Barrio, Noelia, Gehlenborg, Nils, Ghassemi, Marzyeh, Gutiérrez-Sacristán, Alba, Hanauer, David A, Holmes, John H, Hong, Chuan, Klann, Jeffrey G, Loh, Ne Hooi Will, Luo, Yuan, Mandl, Kenneth D, Daniar, Mohamad, Moore, Jason H, Murphy, Shawn N, Neuraz, Antoine, Ngiam, Kee Yuan, Omenn, Gilbert S, Palmer, Nathan, Patel, Lav P, Pedrera-Jiménez, Miguel, Sliz, Piotr, South, Andrew M, Tan, Amelia Li Min, Taylor, Deanne M, Taylor, Bradley W, Torti, Carlo, Vallejos, Andrew K, Wagholikar, Kavishwar B, Weber, Griffin M, Cai, Tianxi

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Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers w... by Hey, John A., Abushakra, Susan, Blennow, Kaj, Reiman, Eric M., Hort, Jakub, Prins, Niels D., Sheardova, Katerina, Kesslak, Patrick, Shen, Larry, Zhu, Xinyi, Albayrak, Adem, Paul, Jijo, Schaefer, Jean F., Power, Aidan, Tolar, Martin

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Abstract 28: Identification of multisite real-world patient cohorts to enable immunotherapy utilization and safety assessment by Del Vecchio Fitz, Catherine, Eldridge, Elizabeth, Antonopoulos, Alyssa, Petrone, Paula, Caldwell, Will, Corbett, Ed, Flaster, Amy, Rimmasch, Holly, Albayrak, Adem, Sanders, Dale, Mahmood, Sadiqa, Stupka, Elia

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Distinguishing Admissions Specifically for COVID-19 From Incidental SARS-CoV-2 Admissions: National Retrospective Electronic Health Record Study by Klann, Jeffrey G, Strasser, Zachary H, Hutch, Meghan R, Kennedy, Chris J, Marwaha, Jayson S, Morris, Michele, Samayamuthu, Malarkodi Jebathilagam, Pfaff, Ashley C, Estiri, Hossein, South, Andrew M, Weber, Griffin M, Yuan, William, Avillach, Paul, Wagholikar, Kavishwar B, Luo, Yuan, Omenn, Gilbert S, Visweswaran, Shyam, Holmes, John H, Xia, Zongqi, Brat, Gabriel A, Murphy, Shawn N

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International Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: Retrospective Cohort Study by Weber, Griffin M, Zhang, Harrison G, L'Yi, Sehi, Bonzel, Clara-Lea, Hong, Chuan, Avillach, Paul, Gutiérrez-Sacristán, Alba, Palmer, Nathan P, Tan, Amelia Li Min, Wang, Xuan, Yuan, William, Gehlenborg, Nils, Alloni, Anna, Amendola, Danilo F, Bellasi, Antonio, Bellazzi, Riccardo, Beraghi, Michele, Bucalo, Mauro, Chiovato, Luca, Cho, Kelly, Dagliati, Arianna, Estiri, Hossein, Follett, Robert W, García Barrio, Noelia, Hanauer, David A, Henderson, Darren W, Ho, Yuk-Lam, Holmes, John H, Hutch, Meghan R, Kavuluru, Ramakanth, Kirchoff, Katie, Klann, Jeffrey G, Krishnamurthy, Ashok K, Le, Trang T, Liu, Molei, Loh, Ne Hooi Will, Lozano-Zahonero, Sara, Luo, Yuan, Maidlow, Sarah, Makoudjou, Adeline, Malovini, Alberto, Martins, Marcelo Roberto, Moal, Bertrand, Morris, Michele, Mowery, Danielle L, Murphy, Shawn N, Neuraz, Antoine, Ngiam, Kee Yuan, Okoshi, Marina P, Omenn, Gilbert S, Patel, Lav P, Pedrera Jiménez, Miguel, Prudente, Robson A, Samayamuthu, Malarkodi Jebathilagam, Sanz Vidorreta, Fernando J, Schriver, Emily R, Schubert, Petra, Serrano Balazote, Pablo, Tan, Byorn Wl, Tanni, Suzana E, Tibollo, Valentina, Visweswaran, Shyam, Wagholikar, Kavishwar B, Xia, Zongqi, Zöller, Daniela, Kohane, Isaac S, Cai, Tianxi, South, Andrew M, Brat, Gabriel A

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Acute respiratory distress syndrome after SARS-CoV-2 infection on young adult population: International observational federated study based on electronic health records through the... by Moal, Bertrand, Orieux, Arthur, Ferté, Thomas, Neuraz, Antoine, Brat, Gabriel A, Avillach, Paul, Bonzel, Clara-Lea, Cai, Tianxi, Cho, Kelly, Cossin, Sébastien, Griffier, Romain, Hanauer, David A, Haverkamp, Christian, Ho, Yuk-Lam, Hong, Chuan, Hutch, Meghan R, Klann, Jeffrey G, Le, Trang T, Loh, Ne Hooi Will, Luo, Yuan, Makoudjou, Adeline, Morris, Michele, Mowery, Danielle L, Olson, Karen L, Patel, Lav P, Samayamuthu, Malarkodi J, Sanz Vidorreta, Fernando J, Schriver, Emily R, Schubert, Petra, Verdy, Guillaume, Visweswaran, Shyam, Wang, Xuan, Weber, Griffin M, Xia, Zongqi, Yuan, William, Zhang, Harrison G, Zöller, Daniela, Kohane, Isaac S, Boyer, Alexandre, Jouhet, Vianney

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COVID-19 Evidence Accelerator: A parallel analysis to describe the use of Hydroxychloroquine with or without Azithromycin among hospitalized COVID-19 patients by Stewart, Mark, Rodriguez-Watson, Carla, Albayrak, Adem, Asubonteng, Julius, Belli, Andrew, Brown, Thomas, Cho, Kelly, Das, Ritankar, Eldridge, Elizabeth, Gatto, Nicolle, Gelman, Alice, Gerlovin, Hanna, Goldberg, Stuart L, Hansen, Eric, Hirsch, Jonathan, Ho, Yuk-Lam, Ip, Andrew, Izano, Monika, Jones, Jason, Justice, Amy C, Klesh, Reyna, Kuranz, Seth, Lam, Carson, Mao, Qingqing, Mataraso, Samson, Mera, Robertino, Posner, Daniel C, Rassen, Jeremy A, Siefkas, Anna, Schrag, Andrew, Tourassi, Georgia, Weckstein, Andrew, Wolf, Frank, Bhat, Amar, Winckler, Susan, Sigal, Ellen V, Allen, Jeff

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Long-term kidney function recovery and mortality after COVID-19-associated acute kidney injury: an international multi-centre observational cohort study by Tan, Bryce W.Q., Moal, Bertrand, Neuraz, Antoine, Visweswaran, Shyam, Hanauer, David A., Maidlow, Sarah E., Avillach, Paul, Serrano Balazote, Pablo, Loh, Ne Hooi Will, Chiudinelli, Lorenzo, Cai, Tianxi, Omenn, Gilbert S., Holmes, John H., Ngiam, Kee Yuan, Agapito, Giuseppe, Albi, Giuseppe, Alloni, Anna, Angoulvant, François, Anthony, Li L.L.J., Aronow, Bruce J., Balshi, James, Bellasi, Antonio, Bernal-Sobrino, José Luis, Bhatnagar, Surbhi, Bosari, Silvano, Bourgeois, Florence T., Bradford, Robert L., Bryant, William A., Cannataro, Mario, Chiudinelli, Lorenzo, Colicchio, Tiago K., Cormont, Sylvie, Dagliati, Arianna, Daniar, Mohamad, Daniel, Christel, Dubiel, Julien, DuVall, Scott L., Estiri, Hossein, Fan, Shirley, Follett, Robert W., Ganslandt, Thomas, Gehlenborg, Nils, Getzen, Emily J., Geva, Alon, Griffier, Romain, Gutiérrez-Sacristán, Alba, Guzzi, Pietro H., Henderson, Darren W., Ho, Yuk-Lam, Holmes, John H., Hong, Chuan, Kavuluru, Ramakanth, Kernan, Kate F., Klann, Jeffrey G., Krantz, Ian D., Krishnamurthy, Ashok K., Leblanc, Judith, Lemaitre, Guillaume, Liu, Molei, Long, Qi, Maidlow, Sarah E., Makoudjou, Adeline, Makwana, Simran, Malovini, Alberto, Mazzotti, Diego R., Milano, Marianna, Moraleda, Cinta, Mowery, Danielle L., Naughton, Thomas P., Ngiam, Kee Yuan, Njoroge, Wanjiku F.M., Omenn, Gilbert S., Orlova, Nina, Ostasiewski, Brian D., Palmer, Nathan P., Paris, Nicolas, Patel, Lav P., Priya, Tanu, Raskin, Maryna, Rieg, Siegbert, Roig-Domínguez, Gustavo, Sáez, Carlos, Schubert, Petra, Schuettler, Juergen, Shah, Mohsin, Son, Jiyeon, Sonday, Charles, Tan, Bryce W.Q., Terriza-Torres, Ana I., Tibollo, Valentina, Tippmann, Patric, Vallejos, Andrew K., Vella, Margaret E., Vie, Jill-Jênn, Vitacca, Michele, Wassermann, Demian, Ye, Ye, Yehya, Nadir, Zambelli, Alberto, Zhang, Harrison G.

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Multinational characterization of neurological phenotypes in patients hospitalized with COVID-19 by Le, Trang T., Gutiérrez-Sacristán, Alba, Son, Jiyeon, Hong, Chuan, South, Andrew M., Beaulieu-Jones, Brett K., Loh, Ne Hooi Will, Luo, Yuan, Morris, Michele, Ngiam, Kee Yuan, Patel, Lav P., Samayamuthu, Malarkodi J., Schriver, Emily, Tan, Amelia L. M., Moore, Jason, Cai, Tianxi, Omenn, Gilbert S., Avillach, Paul, Kohane, Isaac S., Visweswaran, Shyam, Mowery, Danielle L., Xia, Zongqi

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Abstract 2288: Assessing patient trial readiness for precision cancer medicine clinical trials through computational trial matching and rule-based logic applied to genomic and clin... by Fitz, Catherine Del Vecchio, Do, Khanh, Lindsay, James, Hector-Barry, Suzanne, Zwiesler, Zachary, Kumari, Priti, Mazor, Tali, Monrose, Tamba, Albayrak, Adem, Methot, John, Hassett, Michael, Shapiro, Geoffrey, Cerami, Ethan

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Multinational characterization of neurological phenotypes in patients hospitalized with COVID-19 by Le, Trang, Gutiérrez-Sacristán, Alba, Son, Jiyeon, Hong, Chuan, South, Andrew, Beaulieu-Jones, Brett, Loh, Ne Hooi Will, Luo, Yuan, Morris, Michele, Ngiam, Kee Yuan, Patel, Lav, Samayamuthu, Malarkodi, Schriver, Emily, Tan, Amelia, Moore, Jason, Cai, Tianxi, Omenn, Gilbert, Avillach, Paul, Kohane, Isaac, Visweswaran, Shyam, Mowery, Danielle, Xia, Zongqi, Aaron, James, Agapito, Giuseppe, Albayrak, Adem, Alessiani, Mario, Amendola, Danilo, Angoulvant, François, Anthony, Li, Aronow, Bruce, Atz, Andrew, Balshi, James, Bell, Douglas, Bellasi, Antonio, Bellazzi, Riccardo, Benoit, Vincent, Beraghi, Michele, Bernal Sobrino, José Luis, Bernaux, Mélodie, Bey, Romain, Blanco Martínez, Alvar, Boeker, Martin, Bonzel, Clara-Lea, Booth, John, Bosari, Silvano, Bourgeois, Florence, Bradford, Robert, Brat, Gabriel, Bréant, Stéphane, Brown, Nicholas, Bryant, William, Bucalo, Mauro, Burgun, Anita, Cannataro, Mario, Carmona, Aldo, Caucheteux, Charlotte, Champ, Julien, Chen, Krista, Chen, Jin, Chiovato, Luca, Chiudinelli, Lorenzo, Cimino, James, Colicchio, Tiago, Cormont, Sylvie, Cossin, Sébastien, Craig, Jean, Cruz Bermúdez, Juan Luis, Cruz Rojo, Jaime, Dagliati, Arianna, Daniar, Mohamad, Daniel, Christel, Davoudi, Anahita, Devkota, Batsal, Dubiel, Julien, Esteve, Loic, Fan, Shirley, Follett, Robert, Gaiolla, Paula, Ganslandt, Thomas, García Barrio, Noelia, Garmire, Lana, Gehlenborg, Nils, Geva, Alon, Gradinger, Tobias, Gramfort, Alexandre, Griffier, Romain, Griffon, Nicolas, Grisel, Olivier, Hanauer, David, Haverkamp, Christian, He, Bing, Henderson, Darren, Hilka, Martin, Holmes, John, Horki, Petar, Huling, Kenneth, Hutch, Meghan, Issitt, Richard, Jannot, Anne Sophie, Jouhet, Vianney

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International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries by Bourgeois, Florence T, Gutiérrez-Sacristán, Alba, Keller, Mark S, Liu, Molei, Hong, Chuan, Bonzel, Clara-Lea, Tan, Amelia L M, Aronow, Bruce J, Boeker, Martin, Booth, John, Cruz Rojo, Jaime, Devkota, Batsal, García Barrio, Noelia, Gehlenborg, Nils, Geva, Alon, Hanauer, David A, Hutch, Meghan R, Issitt, Richard W, Klann, Jeffrey G, Luo, Yuan, Mandl, Kenneth D, Mao, Chengsheng, Moal, Bertrand, Moshal, Karyn L, Murphy, Shawn N, Neuraz, Antoine, Ngiam, Kee Yuan, Omenn, Gilbert S, Patel, Lav P, Jiménez, Miguel Pedrera, Sebire, Neil J, Balazote, Pablo Serrano, Serret-Larmande, Arnaud, South, Andrew M, Spiridou, Anastasia, Taylor, Deanne M, Tippmann, Patric, Visweswaran, Shyam, Weber, Griffin M, Kohane, Isaac S, Cai, Tianxi, Avillach, Paul

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Clinical phenotypes and outcomes in children with multisystem inflammatory syndrome across SARS-CoV-2 variant eras: a multinational study from the 4CE consortium by Gutiérrez-Sacristán, Alba, Makwana, Simran, Omenn, Gilbert S., Bonzel, Clara-Lea, Issitt, Richard W., Laird-Gion, Jessica, Mandl, Kenneth D., Moshal, Karyn L., Amendola, Danilo F., Anthony, Li LLJ, Atz, Andrew, Panickan, Vidul Ayakulangara, Badenes, Rafael, Beaulieu-Jones, Brendin R., Bellasi, Antonio, Bellazzi, Riccardo, Bernaux, Mélodie, Bey, Romain, Bonzel, Clara-Lea, Booth, John, Brat, Gabriel A., Bruno, Raffaele, Bryant, William A., Carmona, Aldo, Caucheteux, Charlotte, Chen, Krista Y., Cormont, Sylvie, Cruz-Rojo, Jaime, Das, Priyam, Duan, Rui, Getzen, Emily J., González, Tomás González, Gradinger, Tobias, Griffon, Nicolas, Grisel, Olivier, Hazard, Derek Y., He, Bing, Ho, Yuk-Lam, Huling, Kenneth M., Hutch, Meghan R., Kainth, Mundeep K., Kernan, Kate F., Key, Daniel A., Klann, Jeffrey G., Krishnamurthy, Ashok K., Leblanc, Judith, Lemaitre, Guillaume, Lenert, Leslie, Liu, Molei, Long, Qi, Lozano-Zahonero, Sara, Luo, Yuan, Lynch, Kristine E., Maidlow, Sarah E., Makoudjou, Adeline, Makwana, Simran, Malovini, Alberto, Masino, Aaron J., Mazzotti, Diego R., Mensch, Arthur, Moraleda, Cinta, Morris, Jeffrey S., Morris, Michele, Moshal, Karyn L., Mousavi, Sajad, Murphy, Shawn N., Naughton, Thomas P., Neuraz, Antoine, Ngiam, Kee Yuan, Omenn, Gilbert S., Orlova, Nina, Ostasiewski, Brian D., Palmer, Nathan P., Patel, Lav P., Pfaff, Emily R., Prunotto, Andrea, Quirós-González, Víctor, Ramoni, Rachel B., Roig-Domínguez, Gustavo, Sacchi, Paolo, Santhanam, Nandhini, Schriver, Emily R., Schubert, Petra, Schuettler, Juergen, Silvio, Domenick, Sliz, Piotr, Sonday, Charles, Tan, Amelia LM, Tan, Bryce W.Q., Terriza-Torres, Ana I., Tippmann, Patric, Vallejos, Andrew K., Vella, Margaret E., Vie, Jill-Jênn, Visweswaran, Shyam, Vitacca, Michele, Xiong, Xin, Ye, Ye, Yehya, Nadir, Zhang, Harrison G.

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Hospitalizations Associated With Mental Health Conditions Among Adolescents in the US and France During the COVID-19 Pandemic by Gutiérrez-Sacristán, Alba, Serret-Larmande, Arnaud, Hutch, Meghan R, Sáez, Carlos, Aronow, Bruce J, Bhatnagar, Surbhi, Bonzel, Clara-Lea, Cai, Tianxi, Devkota, Batsal, Hanauer, David A, Loh, Ne Hooi Will, Luo, Yuan, Moal, Bertrand, Ahooyi, Taha Mohseni, Njoroge, Wanjiku F M, Omenn, Gilbert S, Sanchez-Pinto, L Nelson, South, Andrew M, Sperotto, Francesca, Tan, Amelia L M, Taylor, Deanne M, Verdy, Guillaume, Visweswaran, Shyam, Xia, Zongqi, Zahner, Janet, Avillach, Paul, Bourgeois, Florence T

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Characterization of long COVID temporal sub-phenotypes by distributed representation learning from electronic health record data: a cohort study by Dagliati, Arianna, Klann, Jeffrey G., Henderson, Darren W., Tan, Bryce W.Q., Bellazzi, Riccardo, Agapito, Giuseppe, Albayrak, Adem, Albi, Giuseppe, Alloni, Anna, François Angoulvant, Anthony, Li L.L.J., Azevedo, Paula S., Balshi, James, Beaulieu-Jones, Brett K., Bellasi, Antonio, Bellazzi, Riccardo, Benoit, Vincent, Bernal-Sobrino, José Luis, Bernaux, Mélodie, Blanco-Martínez, Alvar, Booth, John, Brown, Nicholas W., Bruno, Raffaele, Bucholz, Emily, Burgun, Anita, Cannataro, Mario, Chen, Jin, Chen, Krista Y., Chiovato, Luca, Chiudinelli, Lorenzo, Cho, Kelly, Cimino, James J., Colicchio, Tiago K., Cossin, Sébastien, Cruz-Bermúdez, Juan Luis, Dagliati, Arianna, Daniar, Mohamad, Das, Priyam, Devkota, Batsal, Follett, Robert W., Ganslandt, Thomas, Barrio, Noelia García-, Getzen, Emily J., Gramfort, Alexandre, Griffon, Nicolas, Grisel, Olivier, Gutiérrez-Sacristán, Alba, Hanauer, David A., Haverkamp, Christian, Hilka, Martin, Holmes, John H., Huling, Kenneth M., Jannot, Anne Sophie, Jouhet, Vianney, Kirchoff, Katie, Klann, Jeffrey G., Kraska, Detlef, Krishnamurthy, Ashok K., L'Yi, Sehi, Leprovost, Damien, Will Loh, Ne Hooi, Lynch, Kristine E., Mensch, Arthur, Moshal, Karyn L., Mousavi, Sajad, Murad, Douglas A., Neuraz, Antoine, Newburger, Jane, Norman, James B., Obeid, Jihad, Omenn, Gilbert S., Pizzimenti, Sara, Rieg, Siegbert, Salamanca, Elisa, Samayamuthu, Malarkodi Jebathilagam, Sanchez-Pinto, L. Nelson, Santos, Janaina C.C., Sanz Vidorreta, Fernando J., Savino, Maria, Sebire, Neil J., Serret-Larmande, Arnaud, Shah, Mohsin, Son, Jiyeon, Sonday, Charles, Spiridou, Anastasia, Strasser, Zachary H., Tan, Amelia L.M., Terriza-Torres, Ana I., Tibollo, Valentina, Toh, Emma M.S., Torti, Carlo, Tseng, Yi-Ju, Varoquaux, Gael, Verdy, Guillaume, Vie, Jill-Jênn, Wong, Scott, Zhang, Harrison G., Zuccaro, Valentina, Holmes, John H., Estiri, Hossein

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