A Bicyclic Analog of the Linear Peptide Arodyn Is a Potent and Selective Kappa Opioid Receptor Antagonist by Gisemba, Solomon A, Ferracane, Michael J, Murray, Thomas F, Aldrich, Jane V

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An analog of [d-Trp]CJ-15,208 exhibits kappa opioid receptor antagonism following oral administration and prevents stress-induced reinstatement of extinguished morphine conditioned... by Brice-Tutt, Ariana C., Eans, Shainnel O., Yakovlev, Dmitry, Aldrich, Jane V., McLaughlin, Jay P.

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Phenylalanine Stereoisomers of CJ-15,208 and [d-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles by Brice-Tutt, Ariana C, Senadheera, Sanjeewa N, Ganno, Michelle L, Eans, Shainnel O, Khaliq, Tanvir, Murray, Thomas F, McLaughlin, Jay P, Aldrich, Jane V

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Zyklophin, a Systemically Active Selective Kappa Opioid Receptor Peptide Antagonist with Short Duration of Action by Aldrich, Jane V., Patkar, Kshitij A., McLaughlin, Jay P.

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Tryptophan Substitution in CJ-15,208 ( cyclo [Phe-D-Pro-Phe-Trp]) Introduces δ-Opioid Receptor Antagonism, Preventing Antinociceptive Tolerance and Stress-Induced Reinstatement of... by Scherrer, Kristen H, Eans, Shainnel O, Medina, Jessica M, Senadheera, Sanjeewa N, Khaliq, Tanvir, Murray, Thomas F, McLaughlin, Jay P, Aldrich, Jane V

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Optimized Ring Closing Metathesis Reaction Conditions To Suppress Desallyl Side Products in the Solid-Phase Synthesis of Cyclic Peptides Involving Tyrosine(O‑allyl) by Gisemba, Solomon A, Aldrich, Jane V

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Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa... by Gisemba, Solomon A, Ferracane, Michael J, Murray, Thomas F, Aldrich, Jane V

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Quantification of kappa opioid receptor ligand potency, efficacy and desensitization using a real-time membrane potential assay by Zhao, Yuanzi, Joshi, Anand A., Aldrich, Jane V., Murray, Thomas F.

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Peptide Kappa Opioid Receptor Ligands: Potential for Drug Development by Aldrich, Jane V., McLaughlin, Jay P.

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Design, synthesis, and opioid activity of arodyn analogs cyclized by ring-closing metathesis involving Tyr(allyl) by Fang, Wei-Jie, Murray, Thomas F., Aldrich, Jane V.

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Multifunctional opioid receptor agonism and antagonism by a novel macrocyclic tetrapeptide prevents reinstatement of morphine‐seeking behaviour by Brice‐Tutt, Ariana C., Wilson, Lisa L., Eans, Shainnel O., Stacy, Heather M., Simons, Chloe A., Simpson, Grant G., Coleman, Jeremy S., Ferracane, Michael J., Aldrich, Jane V., McLaughlin, Jay P.

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Alanine scan of the opioid peptide dynorphin B amide by Joshi, Anand A., Murray, Thomas F., Aldrich, Jane V.

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Analogs of the κ opioid receptor antagonist arodyn cyclized by ring-closing metathesis retain κ opioid receptor affinity, selectivity and κ opioid receptor antagonism by Fang, Wei-Jie, Murray, Thomas F., Aldrich, Jane V.

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Structure–Activity Relationships of the Peptide Kappa Opioid Receptor Antagonist Zyklophin by Joshi, Anand A, Murray, Thomas F, Aldrich, Jane V

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Design, Synthesis, and Characterization of the Macrocyclic Tetrapeptide cyclo[Pro-Sar-Phe‑d‑Phe]: A Mixed Opioid Receptor Agonist–Antagonist Following Oral Administration by Ferracane, Michael J, Brice-Tutt, Ariana C, Coleman, Jeremy S, Simpson, Grant G, Wilson, Lisa L, Eans, Shainnel O, Stacy, Heather M, Murray, Thomas F, McLaughlin, Jay P, Aldrich, Jane V

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Development of a robust, sensitive and selective liquid chromatography-tandem mass spectrometry assay for the quantification of the novel macrocyclic peptide kappa opioid receptor... by Khaliq, Tanvir, Williams, Todd D., Senadheera, Sanjeewa N., Aldrich, Jane V.

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Targeting inhibitor 2 of protein phosphatase 2A as a therapeutic strategy for prostate cancer treatment by Mukhopadhyay, Archana, Tabanor, Kayann, Chaguturu, Rathnam, Aldrich, Jane V

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Involvement of dynorphin and kappa opioid receptor in yohimbine-induced reinstatement of heroin seeking in rats by Zhou, Yan, Leri, Francesco, Grella, Stephanie L., Aldrich, Jane V., Kreek, Mary Jeanne

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Two short-acting kappa opioid receptor antagonists (zyklophin and LY2444296) exhibited different behavioral effects from the long-acting antagonist norbinaltorphimine in mouse anxi... by Huang, Peng, Yakovleva, Tatyana, Aldrich, Jane V., Tunis, Julia, Parry, Christopher, Liu-Chen, Lee-Yuan

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Opioid peptides: potential for drug development by Aldrich, Jane V., McLaughlin, Jay P.

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