Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network by Bush, WS, Crosslin, DR, Owusu-Obeng, A, Wallace, J, Almoguera, B, Basford, MA, Bielinski, SJ, Carrell, DS, Connolly, JJ, Crawford, D, Doheny, KF, Gallego, CJ, Gordon, AS, Keating, B, Kirby, J, Kitchner, T, Manzi, S, Mejia, AR, Pan, V, Perry, CL, Peterson, JF, Prows, CA, Ralston, J, Scott, SA, Scrol, A, Smith, M, Stallings, SC, Veldhuizen, T, Wolf, W, Volpi, S, Wiley, K, Li, R, Manolio, T, Bottinger, E, Brilliant, MH, Carey, D, Chisholm, RL, Chute, CG, Haines, JL, Hakonarson, H, Harley, JB, Holm, IA, Kullo, IJ, Jarvik, GP, Larson, EB, McCarty, CA, Williams, MS, Denny, JC, Rasmussen-Torvik, LJ, Roden, DM, Ritchie, MD

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Design and Anticipated Outcomes of the eMERGE-PGx Project: A Multicenter Pilot for Preemptive Pharmacogenomics in Electronic Health Record Systems by Rasmussen-Torvik, L J, Stallings, S C, Gordon, A S, Almoguera, B, Basford, M A, Bielinski, S J, Brautbar, A, Brilliant, M H, Carrell, D S, Connolly, J J, Crosslin, D R, Doheny, K F, Gallego, C J, Gottesman, O, Kim, D S, Leppig, K A, Li, R, Lin, S, Manzi, S, Mejia, A R, Pacheco, J A, Pan, V, Pathak, J, Perry, C L, Peterson, J F, Prows, C A, Ralston, J, Rasmussen, L V, Ritchie, M D, Sadhasivam, S, Scott, S A, Smith, M, Vega, A, Vinks, A A, Volpi, S, Wolf, W A, Bottinger, E, Chisholm, R L, Chute, C G, Haines, J L, Harley, J B, Keating, B, Holm, I A, Kullo, I J, Jarvik, G P, Larson, E B, Manolio, T, McCarty, C A, Nickerson, D A, Scherer, S E, Williams, M S, Roden, D M, Denny, J C

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Five years’ experience of the clinical exome sequencing in a Spanish single center by Arteche-López, A., Ávila-Fernández, A., Riveiro Álvarez, R., Almoguera, B., Bustamante Aragonés, A., Martin-Merida, I., López Martínez, M. A., Giménez Pardo, A., Vélez-Monsalve, C., Gallego Merlo, J., García Vara, I., Blanco-Kelly, F., Tahsin Swafiri, S., Lorda Sánchez, I., Trujillo Tiebas, M. J., Ayuso, C.

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Risk of pre‐eclampsia in patients with a maternal genetic predisposition to common medical conditions: a case–control study by Gray, KJ, Kovacheva, VP, Mirzakhani, H, Bjonnes, AC, Almoguera, B, Wilson, ML, Ingles, SA, Lockwood, CJ, Hakonarson, H, McElrath, TF, Murray, JC, Norwitz, ER, Karumanchi, SA, Bateman, BT, Keating, BJ, Saxena, R

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Novel human pathological mutations. Gene symbol: CRB1. Disease: Leber congenital amaurosis by Vallespin, Elena, Avila-Fernandez, A, Velez-Monsalve, C, Almoguera, B, Martinez-Garcia, M, Gomez-Dominguez, B, Gonzalez-Roubaud, C, Cantalapiedra, D, Trujillo-Tiebas, M J, Ayuso, C

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Novel human pathological mutations. Gene symbol: LCA5. Disease: Leber congenital amaurosis by Vallespin, E, Avila-Fernandez, A, Almoguera, B, Velez-Monsalve, C, Cantalapiedra, D, Garcia-Hoyos, M, Riveiro-Alvarez, R, Aguirre-Lamban, J, Bustamante-Aragones, A, Trujillo-Tiebas, M J, Ayuso, C

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Novel human pathological mutations. Gene symbol: LCA5. Disease: Leber Congenital Amaurosis (LCA) by Vallespin, Elena, Avila-Fernandez, A, Almoguera, B, Cantalapiedra, D, Garcia-Hoyos, M, Riveiro-Alvarez, R, Aguirre-Lamban, J, Bustamante-Aragones, A, Trujillo-Tiebas, M J, Ayuso, C

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Mitochondrial haplogroups associated with end-stage heart failure and coronary allograft vasculopathy in heart transplant patients by Gallardo, M. Esther, García-Pavía, Pablo, Chamorro, Raquel, Vázquez, María E., Gómez-Bueno, Manuel, Millán, Isabel, Almoguera, Berta, Domingo, Verónica, Segovia, Javier, Vilches, Carlos, Alonso-Pulpón, Luis, Garesse, Rafael, Bornstein, Belén

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Mutation analysis at codon 838 of the Guanylate Cyclase 2D gene in Spanish families with autosomal dominant cone, cone-rod, and macular dystrophies by Garcia-Hoyos, Maria, Auz-Alexandre, Carmen Laura, Almoguera, Berta, Cantalapiedra, Diego, Riveiro-Alvarez, Rosa, Lopez-Martinez, Miguel Angel, Gimenez, Ascension, Blanco-Kelly, Fiona, Avila-Fernandez, Almudena, Trujillo-Tiebas, Maria Jose, Garcia-Sandoval, Blanca, Ramos, Carmen, Ayuso, Carmen

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Identification of Four Novel Loci in Asthma in European American and African American Populations by Almoguera, Berta, Vazquez, Lyam, Mentch, Frank, Connolly, John, Pacheco, Jennifer A, Sundaresan, Agnes S, Peissig, Peggy L, Linneman, James G, McCarty, Catherine A, Crosslin, David, Carrell, David S, Lingren, Todd, Namjou-Khales, Bahram, Harley, John B, Larson, Eric, Jarvik, Gail P, Brilliant, Murray, Williams, Marc S, Kullo, Iftikhar J, Hysinger, Erik B, Sleiman, Patrick M A, Hakonarson, Hakon

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Mendelian randomization analysis demonstrates that low vitamin D is unlikely causative for pediatric asthma by Hysinger, Erik B., MD, Roizen, Jeffrey D., MD, PhD, Mentch, Frank D., PhD, Vazquez, Lyam, MD, Connolly, John J., PhD, Bradfield, Jonathan P., BS, Almoguera, Berta, PhD, Sleiman, Patrick M., PhD, Allen, Julian L., MD, Levine, Michael A., MD, Hakonarson, Hakon, MD, PhD

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Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci by Saxena, Richa, Guo, Yiran, Peter, Inga, Gaunt, Tom R., Mega, Jessica L., Li, Yun R., Johnson, Toby, Bruinenberg, Marcel, Gilbert-Diamond, Diane, Rajagopalan, Ramakrishnan, Voight, Benjamin F., Barnard, John, Bauer, Florianne, Bhangale, Tushar, Burton, Paul R., Clarke, Robert, Cooper-DeHoff, Rhonda M., Crook, Errol D., Davey-Smith, George, Day, Ian N., Drenos, Fotios, Furlong, Clement E., Gibson, Quince, Gieger, Christian, Goel, Anuj, Gong, Yan, Hastie, Claire, Humphries, Steve E., Kim, Cecilia E., Kleber, Marcus, Kumari, Meena, Langaee, Taimour Y., Lawlor, Debbie A., Li, Mingyao, Lobmeyer, Maximilian T., Maitland-van der Zee, Anke-Hilse, Meijs, Matthijs F.L., Molony, Cliona M., Musani, Solomon K., Nelson, Christopher P., Newhouse, Stephen J., O'Connell, Jeffery R., Palmen, Jutta, Patel, Sanjey R., Pepine, Carl J., Pettinger, Mary, Price, Thomas S., Rafelt, Suzanne, Ranchalis, Jane, Rasheed, Asif, Rosenthal, Elisabeth, Ruczinski, Ingo, Shen, Haiqing, Spijkerman, Annemieke W.M., Stanton, Alice, Steffes, Michael W., Thorand, Barbara, van der Harst, Pim, van Iperen, Erik P.A., van Vliet-Ostaptchouk, Jana V., Verweij, Niek, Wolffenbuttel, Bruce H.R., Young, Taylor, Zafarmand, M. Hadi, Zmuda, Joseph M., Altshuler, David, Kao, W.H. Linda, Poulter, Neil, Caulfield, Mark, Bhatt, Deepak L., Curtis, Sean P., Danesh, John, Onland-Moret, N. Charlotte, Doevendans, Pieter A., Dorn, Gerald W., Farrall, Martin, FitzGerald, Garret A., Hamsten, Anders, Hofker, Marten H., Jarvik, Gail P., Klungel, Olaf H., Knowler, William C., März, Winfried, Munroe, Patricia B., Bielinski, Susan J., Rader, Daniel J., Reilly, Muredach P., Rich, Stephen S., Rotter, Jerome I., Saleheen, Danish, Schadt, Eric E., Shuldiner, Alan R., Talmud, Philippa J., de Bakker, Paul I.W., McCaffery, Jeanne, Wijmenga, Cisca, Wilson, James G., Bowden, Donald W., Siscovick, David S., Keating, Brendan J.

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CNV Association of Diverse Clinical Phenotypes from eMERGE reveals novel disease biology underlying cardiovascular disease by Glessner, Joseph T., Li, Jin, Desai, Akshatha, Palmer, Melody, Kim, Dokyoon, Lucas, Anastasia Marie, Chang, Xiao, Connolly, John J., Almoguera, Berta, Harley, John B., Jarvik, Gail P., Ritchie, Marylyn D., Sleiman, Patrick M.A., Roden, Dan M., Crosslin, David, Hakonarson, Hakon

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Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology by Hu, Yao, Graff, Mariaelisa, Haessler, Jeffrey, Buyske, Steven, Bien, Stephanie A, Tao, Ran, Highland, Heather M, Nishimura, Katherine K, Zubair, Niha, Lu, Yingchang, Verbanck, Marie, Hilliard, Austin T, Klarin, Derek, Damrauer, Scott M, Ho, Yuk-Lam, Wilson, Peter W. F, Chang, Kyong-Mi, Tsao, Philip S, Cho, Kelly, O'Donnell, Christopher J, Assimes, Themistocles L, Petty, Lauren E, Below, Jennifer E, Dikilitas, Ozan, Schaid, Daniel J, Kosel, Matthew L, Kullo, Iftikhar J, Rasmussen-Torvik, Laura J, Jarvik, Gail P, Feng, Qiping, Wei, Wei-Qi, Larson, Eric B, Mentch, Frank D, Almoguera, Berta, Sleiman, Patrick M, Raffield, Laura M, Correa, Adolfo, Martin, Lisa W, Daviglus, Martha, Matise, Tara C, Ambite, Jose Luis, Carlson, Christopher S, Do, Ron, Loos, Ruth J. F, Wilkens, Lynne R, Le Marchand, Loic, Haiman, Chris, Stram, Daniel O, Hindorff, Lucia A, North, Kari E, Kooperberg, Charles, Cheng, Iona, Peters, Ulrike, Barsh, Gregory S

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Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations by Elbers, Clara C, Guo, Yiran, Tragante, Vinicius, van Iperen, Erik P. A, Lanktree, Matthew B, Castillo, Berta Almoguera, Chen, Fang, Yanek, Lisa R, Wojczynski, Mary K, Li, Yun R, Ferwerda, Bart, Ballantyne, Christie M, Buxbaum, Sarah G, Chen, Yii-Der Ida, Chen, Wei-Min, Cupples, L. Adrienne, Cushman, Mary, Duan, Yanan, Duggan, David, Evans, Michele K, Fernandes, Jyotika K, Fornage, Myriam, Garcia, Melissa, Garvey, W. Timothy, Glazer, Nicole, Gomez, Felicia, Harris, Tamara B, Halder, Indrani, Howard, Virginia J, Keller, Margaux F, Kamboh, M. Ilyas, Kooperberg, Charles, Kritchevsky, Stephen B, LaCroix, Andrea, Liu, Kiang, Liu, Yongmei, Musunuru, Kiran, Newman, Anne B, Onland-Moret, N. Charlotte, Ordovas, Jose, Peter, Inga, Post, Wendy, Redline, Susan, Reis, Steven E, Saxena, Richa, Schreiner, Pamela J, Volcik, Kelly A, Wang, Xingbin, Yusuf, Salim, Zonderland, Alan B, Anand, Sonia S, Becker, Diane M, Psaty, Bruce, Rader, Daniel J, Reiner, Alex P, Rich, Stephen S, Rotter, Jerome I, Sale, Michèle M, Tsai, Michael Y, Borecki, Ingrid B, Hegele, Robert A, Kathiresan, Sekar, Nalls, Michael A, Taylor, Herman A, Hakonarson, Hakon, Sivapalaratnam, Suthesh, Asselbergs, Folkert W, Drenos, Fotios, Wilson, James G, Keating, Brendan J, Gong, Yan

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Loci influencing blood pressure identified using a cardiovascular gene-centric array by Ganesh, S. K., Tragante, V., Guo, W., Guo, Y., Lanktree, M. B., Smith, E. N., Johnson, T., Castillo, B. A., Barnard, J., Baumert, J., Chang, Y.-P. C., Elbers, C. C., Farrall, M., Fischer, M. E., Franceschini, N., Gaunt, T. R., Gho, J. M. I. H., Gieger, C., Gong, Y., Isaacs, A., Kleber, M. E., Leach, I. M., McDonough, C. W., Meijs, M. F. L., Mellander, O., Molony, C. M., Nolte, I. M., Padmanabhan, S., Price, T. S., Rajagopalan, R., Shaffer, J., Shah, S., Shen, H., Soranzo, N., van der Most, P. J., Van Iperen, E. P. A., Van Setten, J., Vonk, J. M., Zhang, L., Beitelshees, A. L., Berenson, G. S., Bhatt, D. L., Boer, J. M. A., Boerwinkle, E., Burkley, B., Burt, A., Chakravarti, A., Chen, W., Cooper-DeHoff, R. M., Curtis, S. P., Dreisbach, A., Duggan, D., Ehret, G. B., Fabsitz, R. R., Fornage, M., Fox, E., Furlong, C. E., Gansevoort, R. T., Hofker, M. H., Hovingh, G. K., Kirkland, S. A., Kottke-Marchant, K., Kutlar, A., LaCroix, A. Z., Langaee, T. Y., Li, Y. R., Lin, H., Liu, K., Maiwald, S., Malik, R., Murugesan, G., Newton-Cheh, C., O'Connell, J. R., Onland-Moret, N. C., Ouwehand, W. H., Palmas, W., Penninx, B. W., Pepine, C. J., Pettinger, M., Polak, J. F., Ramachandran, V. S., Ranchalis, J., Redline, S., Ridker, P. M., Rose, L. M., Scharnag, H., Schork, N. J., Shimbo, D., Shuldiner, A. R., Srinivasan, S. R., Stolk, R. P., Taylor, H. A., Thorand, B., Trip, M. D., van Duijn, C. M., Verschuren, W. M., Wijmenga, C., Winkelmann, B. R., Wyatt, S., Young, J. H.

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Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis by Holmes, Michael V., Lange, Leslie A., Palmer, Tom, Lanktree, Matthew B., North, Kari E., Almoguera, Berta, Buxbaum, Sarah, Chandrupatla, Hareesh R., Elbers, Clara C., Guo, Yiran, Hoogeveen, Ron C., Li, Jin, Li, Yun R., Swerdlow, Daniel I., Cushman, Mary, Price, Tom S., Curtis, Sean P., Fornage, Myriam, Hakonarson, Hakon, Patel, Sanjay R., Redline, Susan, Siscovick, David S., Tsai, Michael Y., Wilson, James G., van der Schouw, Yvonne T., FitzGerald, Garret A., Hingorani, Aroon D., Casas, Juan P., de Bakker, Paul I.W., Rich, Stephen S., Schadt, Eric E., Asselbergs, Folkert W., Reiner, Alex P., Keating, Brendan J.

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Design and Anticipated Outcomes of the eMERGE-PGx Project: A Multi-Center Pilot for Pre-Emptive Pharmacogenomics in Electronic Health Record Systems by Rasmussen-Torvik, Laura J., Stallings, Sarah C., Gordon, Adam S., Almoguera, Berta, Basford, Melissa A., Bielinski, Suzette J., Brautbar, Ariel, Brilliant, Murray, Carrell, David S., Connolly, John, Crosslin, David R., Doheny, Kimberly F., Gallego, Carlos J., Gottesman, Omri, Kim, Daniel Seung, Leppig, Kathleen A., Li, Rongling, Lin, Simon, Manzi, Shannon, Mejia, Ana R., Pacheco, Jennifer A., Pan, Vivian, Pathak, Jyotishman, Perry, Cassandra L., Peterson, Josh F., Prows, Cynthia A., Ralston, James, Rasmussen, Luke V., Ritchie, Marylyn D., Sadhasivam, Senthilkumar, Scott, Stuart A., Smith, Maureen, Vega, Aida, Vinks, Alexander A., Volpi, Simona, Wolf, Wendy A., Bottinger, Erwin, Chisholm, Rex L., Chute, Christopher G., Haines, Jonathan L., Harley, John B., Keating, Brendan, Holm, Ingrid A., Kullo, Iftikhar J., Jarvik, Gail P., Larson, Eric B., Manolio, Teri, McCarty, Catherine A., Nickerson, Deborah A., Scherer, Steven E., Williams, Marc S., Roden, Dan M., Denny, Joshua C.

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First plasmas in the TJ-II flexible Heliac by Alejaldre, C, Alonso, J, Almoguera, L, Ascasíbar, E, Baciero, A, Balbín, R, Blaumoser, M, Botija, J, Brañas, B, Cal, E de la, Cappa, A, Carrasco, R, Castejón, F, Cepero, J R, Cremy, C, Doncel, J, Dulya, C, Estrada, T, Fernández, A, Francés, M, Fuentes, C, García, A, García-Cortés, I, Guasp, J, Herranz, J, Hidalgo, C, Jiménez, J A, Kirpitchev, I, Krivenski, V, Labrador, I, Lapayese, F, Likin, K, Liniers, M, López-Fraguas, A, López-Sánchez, A, Luna, E de la, Martín, R, Martínez, A, Medrano, M, Méndez, P, McCarthy, K, Medina, F, Milligen, B van, Ochando, M, Pacios, L, Pastor, I, Pedrosa, M.A, Peña, A de la, Portas, A, Qin, J, Rodríguez-Rodrigo, L, Salas, A, Sánchez, E, Sánchez, J, Tabarés, F, Tafalla, D, Tribaldos, V, Vega, J, Zurro, B, Akulina, D, Fedyanin, O I, Grebenshchicov, S, Kharchev, N, Meshcheryakov, A, Barth, R, Dijk, G van, Meiden, H van der, Petrov, S

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Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci by Mega, Jessica L., Tare, Archana, Castillo, Berta Almoguera, Li, Yun R., Gilbert-Diamond, Diane, Voight, Benjamin F., Balasubramanyam, Ashok, Barnard, John, Baumert, Jens, Braund, Peter S., Burton, Paul R., Clarke, Robert, de Boer, Anthonius, de Groot, Mark C.H., Drenos, Fotios, Ferguson, Jane, Furlong, Clement E., Gibson, Quince, Gilhuijs-Pederson, Lisa A., Glessner, Joseph T., Grobbee, Diederick E., Hastie, Claire, Humphries, Steve E., Kim, Cecilia E., Kivimaki, Mika, Kleber, Marcus, Meisinger, Christa, Langaee, Taimour Y., Lawlor, Debbie A., Lobmeyer, Maximilian T., Maitland-van der Zee, Anke-Hilse, Meijs, Matthijs F.L., Morrow, David A., Murugesan, Gurunathan, Musani, Solomon K., Nelson, Christopher P., Newhouse, Stephen J., O'Connell, Jeffery R., Padmanabhan, Sandosh, Palmen, Jutta, Patel, Sanjey R., Pepine, Carl J., Pettinger, Mary, Price, Thomas S., Ranchalis, Jane, Rosenthal, Elisabeth, Ruczinski, Ingo, Shah, Sonia, Stanton, Alice, Steffes, Michael W., van der Harst, Pim, van der A, Daphne L., van Iperen, Erik P.A., van Setten, Jessica, van Vliet-Ostaptchouk, Jana V., Verweij, Niek, Wolffenbuttel, Bruce H.R., Young, Taylor, Zmuda, Joseph M., Boehnke, Michael, Altshuler, David, Linda Kao, W.H., Pankow, James S., Cappola, Thomas P., Sever, Peter, Caulfield, Mark, Dominiczak, Anna, Shields, Denis C., Bhatt, Deepak L., Danesh, John, Casas, Juan P., Onland-Moret, N. Charlotte, Dorn, Gerald W., Farrall, Martin, FitzGerald, Garret A., Robert Hegele, Anders Hamsten, Hingorani, Aroon D., Hofker, Marten H., Illig, Thomas, Johnson, Julie A., Knowler, William C., März, Winfried, Meigs, James B., Munroe, Patricia B., Mitchell, Braxton D., Bielinski, Susan J., Rader, Daniel J., Rich, Stephen S., Saleheen, Danish, Samani, Nilesh J., Silverstein, Roy, Kottke-Marchant, Kandice, Watkins, Hugh, Asselbergs, Folkert W., McCaffery, Jeanne, Wijmenga, Cisca, Sabatine, Marc S., Bowden, Donald W., Hakonarson, Hakon, Siscovick, David S.

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