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Germinal center block exacerbates extrafollicular responses and accelerates autoimmune disease progression in a murine lupus model
by
Voss, Lasse Frank
,
Amanda Juul Howarth
,
Thomas Rea Wittenborn
,
Hummelgaard, Sandra
,
Juul-Madsen, Kristian
,
Kastberg, Kristian Savstrup
,
Pedersen, Mathias Krogh
,
Jensen, Lisbeth
,
Papanastasiou, Anastasios D
,
Vorup-Jensen, Thomas
,
Weyer, Kathrin
,
Degn, Soren E
Published in
bioRxiv
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The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus
by
Voss, Lasse F
,
Howarth, Amanda J
,
Wittenborn, Thomas R
,
Hummelgaard, Sandra
,
Juul-Madsen, Kristian
,
Kastberg, Kristian S
,
Pedersen, Mathias K
,
Jensen, Lisbeth
,
Papanastasiou, Anastasios D
,
Vorup-Jensen, Thomas
,
Weyer, Kathrin
,
Degn, Søren E
Published in
Frontiers in immunology
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Frontiers In Immunology
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Subjects
Autoantibodies
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Germinal Centers
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Systemic Lupus Erythematosus
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Animal Models
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Animals
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Antigens
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Autoimmune Diseases
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Autoimmunity
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B Cells
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B-Lymphocytes
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Bcl-6 Protein
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Bone Marrow
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Cell Differentiation
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Chimeras
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Extrafollicular Responses
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Germinal Center
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Immunology
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Kidneys
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Life Sciences & Biomedicine
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Lupus
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