Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development by Ambati, Jayakrishna, Magagnoli, Joseph, Leung, Hannah, Wang, Shao-bin, Andrews, Chris A., Fu, Dongxu, Pandey, Akshat, Sahu, Srabani, Narendran, Siddharth, Hirahara, Shuichiro, Fukuda, Shinichi, Sun, Jian, Pandya, Lekha, Ambati, Meenakshi, Pereira, Felipe, Varshney, Akhil, Cummings, Tammy, Hardin, James W., Edun, Babatunde, Bennett, Charles L., Ambati, Kameshwari, Fowler, Benjamin J., Kerur, Nagaraj, Röver, Christian, Leitinger, Norbert, Werner, Brian C., Stein, Joshua D., Sutton, S. Scott, Gelfand, Bradley D.

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A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration by Narendran, Siddharth, Pereira, Felipe, Yerramothu, Praveen, Apicella, Ivana, Wang, Shao-Bin, Varshney, Akhil, Baker, Kirstie L, Marion, Kenneth M, Ambati, Meenakshi, Ambati, Vidya L, Ambati, Kameshwari, Sadda, Srinivas R, Gelfand, Bradley D, Ambati, Jayakrishna

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Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration by Narendran, Siddharth, Pereira, Felipe, Yerramothu, Praveen, Apicella, Ivana, Wang, Shao-bin, Ambati, Kameshwari, Hirahara, Shuichiro, Kim, Younghee, Ambati, Meenakshi, Ambati, Vidya L., Huang, Peirong, Varshney, Akhil, Nagasaka, Yosuke, Fukuda, Shinichi, Baker, Kirstie L., Marion, Kenneth M., Deussing, Jan M., Sadda, Srinivas R., Gelfand, Bradley D., Ambati, Jayakrishna

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Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P2RX7 purinoceptor antagonism by Al-Khalidi, Rasha, Panicucci, Chiara, Cox, Paul, Chira, Natalia, Róg, Justyna, Young, Christopher N J, McGeehan, Rhiannon E, Ambati, Kameshwari, Ambati, Jayakrishna, Zabłocki, Krzysztof, Gazzerro, Elisabetta, Arkle, Stephen, Bruno, Claudio, Górecki, Dariusz C

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L1 drives IFN in senescent cells and promotes age-associated inflammation by De Cecco, Marco, Ito, Takahiro, Petrashen, Anna P., Elias, Amy E., Skvir, Nicholas J., Criscione, Steven W., Caligiana, Alberto, Brocculi, Greta, Adney, Emily M., Boeke, Jef D., Le, Oanh, Beauséjour, Christian, Ambati, Jayakrishna, Ambati, Kameshwari, Simon, Matthew, Seluanov, Andrei, Gorbunova, Vera, Slagboom, P. Eline, Helfand, Stephen L., Neretti, Nicola, Sedivy, John M.

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Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration by Fukuda, Shinichi, Varshney, Akhil, Fowler, Benjamin J., Wang, Shao-bin, Narendran, Siddharth, Ambati, Kameshwari, Yasuma, Tetsuhiro, Magagnoli, Joseph, Leung, Hannah, Hirahara, Shuichiro, Nagasaka, Yosuke, Yasuma, Reo, Apicella, Ivana, Pereira, Felipe, Makin, Ryan D., Magner, Eamonn, Liu, Xinan, Sun, Jian, Wang, Mo, Baker, Kirstie, Marion, Kenneth M., Huang, Xiwen, Baghdasaryan, Elmira, Ambati, Meenakshi, Ambati, Vidya L., Pandey, Akshat, Pandya, Lekha, Cummings, Tammy, Banerjee, Daipayan, Huang, Peirong, Yerramothu, Praveen, Tolstonog, Genrich V., Held, Ulrike, Erwin, Jennifer A., Paquola, Apua C. M., Herdy, Joseph R., Ogura, Yuichiro, Terasaki, Hiroko, Oshika, Tetsuro, Darwish, Shaban, Singh, Ramendra K., Mozaffari, Saghar, Bhattarai, Deepak, Kim, Kyung Bo, Hardin, James W., Bennett, Charles L., Hinton, David R., Hanson, Timothy E., Röver, Christian, Parang, Keykavous, Kerur, Nagaraj, Liu, Jinze, Werner, Brian C., Sutton, S.Scott, Sadda, Srinivas R., Schumann, Gerald G., Gelfand, Bradley D., Gage, Fred H., Ambati, Jayakrishna

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Kamuvudine-9 Protects Retinal Structure and Function in a Novel Model of Experimental Rhegmatogenous Retinal Detachment by Huang, Peirong, Thomas, Claire C, Ambati, Kameshwari, Dholkawala, Roshni, Nagasaka, Ayami, Yerramothu, Praveen, Narendran, Siddharth, Pereira, Felipe, Nagasaka, Yosuke, Apicella, Ivana, Cai, Xiaoyu, Makin, Ryan D, Magagnoli, Joseph, Stains, Cliff I, Yin, Ruwen, Wang, Shao-Bin, Gelfand, Bradley D, Ambati, Jayakrishna

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DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs by Wang, Shao-Bin, Narendran, Siddharth, Hirahara, Shuichiro, Varshney, Akhil, Pereira, Felipe, Apicella, Ivana, Ambati, Meenakshi, Ambati, Vidya L, Yerramothu, Praveen, Ambati, Kameshwari, Nagasaka, Yosuke, Argyle, Dionne, Huang, Peirong, Baker, Kirstie L, Marion, Kenneth M, Gupta, Kartik, Liu, Bo, Hinton, David R, Canna, Scott W, Sallam, Tamer, Sadda, Srinivas R, Kerur, Nagaraj, Gelfand, Bradley D, Ambati, Jayakrishna

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Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity by Fukuda, Shinichi, Narendran, Siddharth, Varshney, Akhil, Nagasaka, Yosuke, Wang, Shao-Bin, Ambati, Kameshwari, Apicella, Ivana, Pereira, Felipe, Fowler, Benjamin J, Yasuma, Tetsuhiro, Hirahara, Shuichiro, Yasuma, Reo, Huang, Peirong, Yerramothu, Praveen, Makin, Ryan D, Wang, Mo, Baker, Kirstie L, Marion, Kenneth M, Huang, Xiwen, Baghdasaryan, Elmira, Ambati, Meenakshi, Ambati, Vidya L, Banerjee, Daipayan, Bonilha, Vera L, Tolstonog, Genrich V, Held, Ulrike, Ogura, Yuichiro, Terasaki, Hiroko, Oshika, Tetsuro, Bhattarai, Deepak, Kim, Kyung Bo, Feldman, Sanford H, Aguirre, J Ignacio, Hinton, David R, Kerur, Nagaraj, Sadda, Srinivas R, Schumann, Gerald G, Gelfand, Bradley D, Ambati, Jayakrishna

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LINE-1 derepression in senescent cells triggers interferon and inflammaging by Cecco, Marco De, Ito, Takahiro, Petrashen, Anna P., Elias, Amy E., Skvir, Nicholas J., Criscione, Steven W., Caligiana, Alberto, Brocculi, Greta, Adney, Emily M., Boeke, Jef D., Le, Oanh, Beauséjour, Christian, Ambati, Jayakrishna, Ambati, Kameshwari, Simon, Matthew, Seluanov, Andrei, Gorbunova, Vera, Slagboom, P. Eline, Helfand, Stephen L., Neretti, Nicola, Sedivy, John M.

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Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation by De Cecco, Marco, Ito, Takahiro, Petrashen, Anna P., Elias, Amy E., Skvir, Nicholas J., Criscione, Steven W., Caligiana, Alberto, Brocculi, Greta, Adney, Emily M., Boeke, Jef D., Le, Oanh, Beauséjour, Christian, Ambati, Jayakrishna, Ambati, Kameshwari, Simon, Matthew, Seluanov, Andrei, Gorbunova, Vera, Slagboom, P. Eline, Helfand, Stephen L., Neretti, Nicola, Sedivy, John M.

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