A Noncleavable Retro-Binding Peptide That Spans the Substrate Binding Cleft of Serine Proteases. Atomic Structure of Nazumamide A:  Human Thrombin by Nienaber, Vicki L, Amparo, Eugene C

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Discovery of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, an... by Pinto, Donald J. P, Orwat, Michael J, Wang, Shuaige, Fevig, John M, Quan, Mimi L, Amparo, Eugene, Cacciola, Joseph, Rossi, Karen A, Alexander, Richard S, Smallwood, Angela M, Luettgen, Joseph M, Liang, Li, Aungst, Bruce J, Wright, Matthew R, Knabb, Robert M, Wong, Pancras C, Wexler, Ruth R, Lam, Patrick Y. S

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The discovery and structure–activity relationships of pyrano[3,4- b]indole based inhibitors of hepatitis C virus NS5B polymerase by LaPorte, Matthew G., Draper, Tandy L., Miller, Lori E., Blackledge, Charles W., Leister, Lara K., Amparo, Eugene, Hussey, Alison R., Young, Dorothy C., Chunduru, Srinivas K., Benetatos, Christopher A., Rhodes, Gerry, Gopalsamy, Ariamala, Herbertz, Torsten, Burns, Christopher J., Condon, Stephen M.

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1-[3-Aminobenzisoxazol-5′-yl]-3-trifluoromethyl-6-[2′-(3-( R)-hydroxy- N-pyrrolidinyl)methyl-[1,1′]-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4- c]-pyridin-7-one (BMS-740808) a hi... by Pinto, Donald J.P., Orwat, Michael J., Quan, Mimi L., Han, Qi, Galemmo, Robert A., Amparo, Eugene, Wells, Brian, Ellis, Christopher, He, Ming Y., Alexander, Richard S., Rossi, Karen A., Smallwood, Angela, Wong, Pancras C., Luettgen, Joseph M., Rendina, Alan R., Knabb, Robert M., Mersinger, Lawrence, Kettner, Charles, Bai, Steven, He, Kan, Wexler, Ruth R., Lam, Patrick Y.S.

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Phenyltriazolinones as potent factor Xa inhibitors by Quan, Mimi L., Pinto, Donald J.P., Rossi, Karen A., Sheriff, Steven, Alexander, Richard S., Amparo, Eugene, Kish, Kevin, Knabb, Robert M., Luettgen, Joseph M., Morin, Paul, Smallwood, Angela, Woerner, Francis J., Wexler, Ruth R.

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1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydro xy- N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazo lo-[3 ,4- c]-pyridin-7-one (BMS-740808) a... by Pinto, Donald JP, Orwat, Michael J, Quan, Mimi L, Han, Qi, Galemmo, Robert A, Amparo, Eugene, Wells, Brian, Ellis, Christopher, He, Ming Y, Alexander, Richard S, Rossi, Karen A, Smallwood, Angela, Wong, Pancras C, Luettgen, Joseph M, Rendina, Alan R, Knabb, Robert M, Mersinger, Lawrence, Kettner, Charles, Bai, Steven, He, Kan, Wexler, Ruth R, Lam, Patrick YS

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Design and synthesis of potent and selective 5,6-fused heterocyclic thrombin inhibitors by Dominguez, Celia, Duffy, Daniel E., Han, Qi, Alexander, Richard S., Galemmo, Robert A., Park, Jeongsook M., Wong, Pancras C., Amparo, Eugene C., Knabb, Robert M., Luettgen, Joseph, Wexler, Ruth R.

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Discovery of 1-[3-(Aminomethyl)phenyl]- N -[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1 H -pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective... by Pinto, Donald J. P., Orwat, Michael J., Wang, Shuaige, Fevig, John M., Quan, Mimi L., Amparo, Eugene, Cacciola, Joseph, Rossi, Karen A., Alexander, Richard S., Smallwood, Angela M., Luettgen, Joseph M., Liang, Li, Aungst, Bruce J., Wright, Matthew R., Knabb, Robert M., Wong, Pancras C., Wexler, Ruth R., Lam, Patrick Y. S.

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