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L-asparaginase anti-tumor activity in pancreatic cancer is dependent on its glutaminase activity and resistance is mediated by glutamine synthetase
by
Blachier, Jonathan
,
Cleret, Aurore
,
Guerin, Nathalie
,
Gil, Clara
,
Fanjat, Jean-Marc
,
Tavernier, Florian
,
Vidault, Laura
,
Gallix, Fanny
,
Rama, Nicolas
,
Rossignol, Rodrigue
,
Piedrahita, Diana
,
Andrivon, Aurély
,
Châlons-Cottavoz, Marie
,
Aguera, Karine
,
Gay, Fabien
,
Horand, Françoise
,
Laperrousaz, Bastien
Published in
Experimental cell research
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Abstract 2258: Erymethionase (methionine-gamma-lyase encapsulated into red blood cells) potentiates anti-PD-1 therapy in TNBC syngeneic mouse model
by
Sénéchal, Karine
,
Maubant, Sylvie
,
Leblanc, Marie
,
Ciré, Séverine
,
Gallix, Fanny
,
Andrivon, Aurély
,
Duchamp, Olivier
,
Viviani, Fabrice
,
Horand, Françoise
,
Scheer, Alexander
,
BOURGEAUX, Vanessa
Published in
Cancer research (Chicago, Ill.)
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Cancer Research
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Experimental Cell Research
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Subjects
Asparaginase - Pharmacology
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1
Cell Biology
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Drug Resistance
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1
Genetics
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Glutamate-Ammonia Ligase - Genetics
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Glutaminase - Genetics
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Glutamine
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Glutamine - Metabolism
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Glutamine Synthetase
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Humans
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L-Asparaginase
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Life Sciences
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Life Sciences & Biomedicine
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Oncology
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Pancreatic Cancer
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Pancreatic Neoplasms
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Pancreatic Neoplasms - Drug Therapy
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Precursor Cell Lymphoblastic Leukemia-Lymphoma - Drug Therapy
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Science & Technology
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