Improving the refolding yield of interleukin-4 through the optimization of local interactions by Domingues, Helena, Peters, Jörg, Schneider, Karl-Hans, Apeler, Hans, Sebald, Walter, Oschkinat, Hartmut, Serrano, Luis

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Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors by Sommer, Anette, Kopitz, Charlotte, Schatz, Christoph A, Nising, Carl F, Mahlert, Christoph, Lerchen, Hans-Georg, Stelte-Ludwig, Beatrix, Hammer, Stefanie, Greven, Simone, Schuhmacher, Joachim, Braun, Manuela, Zierz, Ruprecht, Wittemer-Rump, Sabine, Harrenga, Axel, Dittmer, Frank, Reetz, Frank, Apeler, Heiner, Jautelat, Rolf, Huynh, Hung, Ziegelbauer, Karl, Kreft, Bertolt

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Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer by Willuda, Jörg, Linden, Lars, Lerchen, Hans-Georg, Kopitz, Charlotte, Stelte-Ludwig, Beatrix, Pena, Carol, Lange, Claudia, Golfier, Sven, Kneip, Christoph, Carrigan, Patricia E, Mclean, Kirk, Schuhmacher, Joachim, von Ahsen, Oliver, Müller, Jörg, Dittmer, Frank, Beier, Rudolf, El Sheikh, Sherif, Tebbe, Jan, Leder, Gabriele, Apeler, Heiner, Jautelat, Rolf, Ziegelbauer, Karl, Kreft, Bertolt

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Abstract 3234: Development of potent and selective antibody-drug conjugates with pyrrole-based KSP inhibitors as novel payload class by Lerchen, Hans-Georg, Wittrock, Sven, Griebenow, Nils, Lobell, Mario, Rebstock, Anne-Sophie, Cancho-Grande, Yolanda, Stelte-Ludwig, Beatrix, Mahlert, Christoph, Greven, Simone, Sommer, Anette, Berndt, Sandra, Terjung, Carsten, Apeler, Heiner, Kreft, Bertolt, Jautelat, Rolf

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Abstract 46: Preclinical activity of novel antibody-drug conjugates with pyrrole-based kinesin spindle protein inhibitors targeting different tumor antigens by Sommer, Anette, Berndt, Sandra, Lerchen, Hans-Georg, Stelte-Ludwig, Beatrix, Wittrock, Sven, Rebstock, Anne-Sophie, Dietz, Lisa, Mahlert, Christoph, Greven, Simone, Griebenow, Nils, Cancho-Grande, Yolanda, Jautelat, Rolf, Apeler, Heiner, Kreft, Bertolt

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Abstract 1771: BAY 1834942 is an immunotherapeutic antibody blocking the novel immune checkpoint regulator CEACAM6 (CD66c) by Willuda, Joerg, Trautwein, Mark, Pinkert, Jessica, Doecke, Wolf-Dietrich, Boehm, Hans-Henning, Wessel, Florian, Ge, Yingzi, Gutierrez, Eva Maria, Weiske, Joerg, Freiberg, Christoph, Gritzan, Uwe, Glueck, Julian, Zopf, Dieter, Golfier, Sven, Ahsen, Oliver von, Zierz, Ruprecht, Wittemer-Rump, Sabine, Apeler, Heiner, Karl, Ziegelbauer, Offringa, Rienk, Kreft, Bertolt, Philipp, Beckhove

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Abstract 4491: FGFR2-ADC potently and selectively inhibits growth of gastric and breast cancer xenograft models by Sommer, Anette, Nising, Carl F., Mahlert, Christoph, Kopitz, Charlotte C., Lerchen, Hans-Georg, Greven, Simone, Stelte-Ludwig, Beatrix, Schuhmacher, Joachim, Zierz, Ruprecht, Wittemer-Rump, Sabine, Schatz, Christoph, Reetz, Frank, Apeler, Heiner, Jautelat, Rolf, Kreft, Bertolt, Ziegelbauer, Karl

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Abstract 5445: Preclinical anti-tumor efficacy of an anti-C4.4a (LYPD3) antibody drug conjugate for the treatment of lung squamous cell carcinoma by Willuda, Joerg, Linden, Lars, Lerchen, Hans-Georg, Kopitz, Charlotte, Golfier, Sven, Bach, Ute, Schumacher, Joachim, Stelte-Ludwig, Beatrix, Ahsen, Oliver Von, Schneider, Claudia, Dittmer, Frank, Beier, Rudolf, El-Sheik, Sherif, Tebbe, Jan, Leder, Gabriele, Apeler, Heiner, Jautelat, Rolf, Kreft, Bertolt, Ziegelbauer, Karl

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