Downregulation of rRNA transcription triggers cell differentiation by Hayashi, Yuki, Kuroda, Takao, Kishimoto, Hiroyuki, Wang, Changshan, Iwama, Atsushi, Kimura, Keiji

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Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription by Oishi, Yumiko, Hayashi, Shinichiro, Isagawa, Takayuki, Oshima, Motohiko, Iwama, Atsushi, Shimba, Shigeki, Okamura, Hitoshi, Manabe, Ichiro

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Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation by Kanatsu-Shinohara, Mito, Yamamoto, Takuya, Toh, Hidehiro, Kazuki, Yasuhiro, Kazuki, Kanako, Imoto, Junichi, Ikeo, Kazuho, Oshima, Motohiko, Shirahige, Katsuhiko, Iwama, Atsushi, Nabeshima, Yoichi, Sasaki, Hiroyuki, Shinohara, Takashi

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The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition by Sashida, Goro, Wang, Changshan, Tomioka, Takahisa, Oshima, Motohiko, Aoyama, Kazumasa, Kanai, Akinori, Mochizuki-Kashio, Makiko, Harada, Hironori, Shimoda, Kazuya, Iwama, Atsushi

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Epigenetics of hematopoietic stem cell aging and disease by Oshima, Motohiko, Iwama, Atsushi

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Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus by Okabe, Atsushi, Funata, Sayaka, Matsusaka, Keisuke, Namba, Hiroe, Fukuyo, Masaki, Rahmutulla, Bahityar, Oshima, Motohiko, Iwama, Atsushi, Fukayama, Masashi, Kaneda, Atsushi

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Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia by Jimbo, Koji, Hattori, Ayuna, Koide, Shuhei, Ito, Takahiro, Sasaki, Katsuhiro, Iwai, Kazuhiro, Nannya, Yasuhito, Iwama, Atsushi, Tojo, Arinobu, Konuma, Takaaki

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Retrotransposons in Werner syndrome-derived macrophages trigger type I interferon-dependent inflammation in an atherosclerosis model by Paul, Sudip Kumar, Oshima, Motohiko, Patil, Ashwini, Sone, Masamitsu, Kato, Hisaya, Maezawa, Yoshiro, Kaneko, Hiyori, Fukuyo, Masaki, Rahmutulla, Bahityar, Ouchi, Yasuo, Tsujimura, Kyoko, Nakanishi, Mahito, Kaneda, Atsushi, Iwama, Atsushi, Yokote, Koutaro, Eto, Koji, Takayama, Naoya

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Deregulated Polycomb functions in myeloproliferative neoplasms by Sashida, Goro, Oshima, Motohiko, Iwama, Atsushi

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Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia by Tanaka, Satomi, Miyagi, Satoru, Sashida, Goro, Chiba, Tetsuhiro, Yuan, Jin, Mochizuki-Kashio, Makiko, Suzuki, Yutaka, Sugano, Sumio, Nakaseko, Chiaki, Yokote, Koutaro, Koseki, Haruhiko, Iwama, Atsushi

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Noncanonical EZH2 drives retinoic acid resistance of variant acute promyelocytic leukemias by Poplineau, Mathilde, Platet, Nadine, Mazuel, Adrien, Hérault, Léonard, N’Guyen, Lia, Koide, Shuhei, Nakajima-Takagi, Yaeko, Kuribayashi, Wakako, Carbuccia, Nadine, Haboub, Loreen, Vernerey, Julien, Oshima, Motohiko, Birnbaum, Daniel, Iwama, Atsushi, Duprez, Estelle

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Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome by Tara, Shiro, Isshiki, Yusuke, Nakajima-Takagi, Yaeko, Oshima, Motohiko, Aoyama, Kazumasa, Tanaka, Tomoyuki, Shinoda, Daisuke, Koide, Shuhei, Saraya, Atsunori, Miyagi, Satoru, Manabe, Ichiro, Matsui, Hirotaka, Koseki, Haruhiko, Bardwell, Vivian J., Iwama, Atsushi

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Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders by Muto, Tomoya, Sashida, Goro, Oshima, Motohiko, Wendt, George R, Mochizuki-Kashio, Makiko, Nagata, Yasunobu, Sanada, Masashi, Miyagi, Satoru, Saraya, Atsunori, Kamio, Asuka, Nagae, Genta, Nakaseko, Chiaki, Yokote, Koutaro, Shimoda, Kazuya, Koseki, Haruhiko, Suzuki, Yutaka, Sugano, Sumio, Aburatani, Hiroyuki, Ogawa, Seishi, Iwama, Atsushi

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Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome by Zhong, Cheng, Kayamori, Kensuke, Koide, Shuhei, Shinoda, Daisuke, Oshima, Motohiko, Nakajima‐Takagi, Yaeko, Nagai, Yurie, Mimura, Naoya, Sakaida, Emiko, Yamazaki, Satoshi, Iwano, Satoshi, Miyawaki, Atsushi, Ito, Ryoji, Tohyama, Kaoru, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Lennox, William, Sheedy, Josephine, Weetall, Marla, Iwama, Atsushi

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Histone lysine methyltransferase SUV39H1 is a potent target for epigenetic therapy of hepatocellular carcinoma by Chiba, Tetsuhiro, Saito, Tomoko, Yuki, Kaori, Zen, Yoh, Koide, Shuhei, Kanogawa, Naoya, Motoyama, Tenyu, Ogasawara, Sadahisa, Suzuki, Eiichiro, Ooka, Yoshihiko, Tawada, Akinobu, Otsuka, Masayuki, Miyazaki, Masaru, Iwama, Atsushi, Yokosuka, Osamu

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Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis by Nakajima-Takagi, Yaeko, Oshima, Motohiko, Takano, Junichiro, Koide, Shuhei, Itokawa, Naoki, Uemura, Shun, Yamashita, Masayuki, Andoh, Shohei, Aoyama, Kazumasa, Isshiki, Yusuke, Shinoda, Daisuke, Saraya, Atsunori, Arai, Fumio, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Koseki, Haruhiko, Ikawa, Tomokatsu, Iwama, Atsushi

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The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells by Miyagi, Satoru, Sroczynska, Patrycja, Kato, Yuko, Nakajima-Takagi, Yaeko, Oshima, Motohiko, Rizq, Ola, Takayama, Naoya, Saraya, Atsunori, Mizuno, Seiya, Sugiyama, Fumihiro, Takahashi, Satoru, Matsuzaki, Yumi, Christensen, Jesper, Helin, Kristian, Iwama, Atsushi

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Poised Lineage Specification in Multipotential Hematopoietic Stem and Progenitor Cells by the Polycomb Protein Bmi1 by Oguro, Hideyuki, Yuan, Jin, Ichikawa, Hitoshi, Ikawa, Tomokatsu, Yamazaki, Satoshi, Kawamoto, Hiroshi, Nakauchi, Hiromitsu, Iwama, Atsushi

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Exposure to microbial products followed by loss of Tet2 promotes myelodysplastic syndrome via remodeling HSCs by Yokomizo-Nakano, Takako, Hamashima, Ai, Kubota, Sho, Bai, Jie, Sorin, Supannika, Sun, Yuqi, Kikuchi, Kenta, Iimori, Mihoko, Morii, Mariko, Kanai, Akinori, Iwama, Atsushi, Huang, Gang, Kurotaki, Daisuke, Takizawa, Hitoshi, Matsui, Hirotaka, Sashida, Goro

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The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis by Mishima, Yuta, Miyagi, Satoru, Saraya, Atsunori, Negishi, Masamitsu, Endoh, Mitsuhiro, Endo, Takaho A., Toyoda, Tetsuro, Shinga, Jun, Katsumoto, Takuo, Chiba, Tetsuhiro, Yamaguchi, Naoto, Kitabayashi, Issay, Koseki, Haruhiko, Iwama, Atsushi

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