A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia by Lam, Stephen, Mandrekar, Sumithra J, Gesthalter, Yaron, Allen Ziegler, Katie L, Seisler, Drew K, Midthun, David E, Mao, Jenny T, Aubry, Marie Christine, McWilliams, Annette, Sin, Don D, Shaipanich, Tawimas, Liu, Gang, Johnson, Evan, Bild, Andrea, Lenburg, Marc E, Ionescu, Diana N, Mayo, John, Yi, Joanne Eunhee, Tazelaar, Henry, Harmsen, William S, Smith, Judith, Spira, Avrum E, Beane, Jennifer, Limburg, Paul J, Szabo, Eva

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MODMatcher: multi-omics data matcher for integrative genomic analysis by Yoo, Seungyeul, Huang, Tao, Campbell, Joshua D, Lee, Eunjee, Tu, Zhidong, Geraci, Mark W, Powell, Charles A, Schadt, Eric E, Spira, Avrum, Zhu, Jun

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Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility by Piccolo, Stephen R, Hoffman, Laura M, Conner, Thomas, Shrestha, Gajendra, Cohen, Adam L, Marks, Jeffrey R, Neumayer, Leigh A, Agarwal, Cori A, Beckerle, Mary C, Andrulis, Irene L, Spira, Avrum E, Moos, Philip J, Buys, Saundra S, Johnson, William Evan, Bild, Andrea H

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Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells by Sommer, Cesar A, Christodoulou, Constantina, Gianotti-Sommer, Andreia, Shen, Steven S, Sailaja, Badi Sri, Hezroni, Hadas, Spira, Avrum, Meshorer, Eran, Kotton, Darrell N, Mostoslavsky, Gustavo

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Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients by Han, Guangchun, Sinjab, Ansam, Hara, Kieko, Treekitkarnmongkol, Warapen, Brennan, Patrick, Chang, Kyle, Bogatenkova, Elena, Sanchez-Espiridion, Beatriz, Behrens, Carmen, Solis, Luisa M, Gao, Boning, Girard, Luc, Zhang, Jianjun, Sepesi, Boris, Cascone, Tina, Byers, Lauren A, Gibbons, Don L, Chen, Jichao, Moghaddam, Seyed Javad, Ostrin, Edwin J, Scheet, Paul, Fujimoto, Junya, Shay, Jerry, Heymach, John V, Minna, John D, Dubinett, Steven, Wistuba, Ignacio I, Stevenson, Christopher S, Spira, Avrum E, Wang, Linghua, Kadara, Humam

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Emergence of a Stage-Dependent Human Liver Disease Signature with Directed Differentiation of Alpha-1 Antitrypsin-Deficient iPS Cells by Wilson, Andrew A., Ying, Lei, Liesa, Marc, Segeritz, Charis-Patricia, Mills, Jason A., Shen, Steven S., Jean, Jyhchang, Lonza, Geordie C., Liberti, Derek C., Lang, Alex H., Nazaire, Jean, Gower, Adam C., Müeller, Franz-Josef, Mehta, Pankaj, Ordóñez, Adriana, Lomas, David A., Vallier, Ludovic, Murphy, George J., Mostoslavsky, Gustavo, Spira, Avrum, Shirihai, Orian S., Ramirez, Maria I., Gadue, Paul, Kotton, Darrell N.

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Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes by Christodoulou, Constantina, Longmire, Tyler A, Shen, Steven S, Bourdon, Alice, Sommer, Cesar A, Gadue, Paul, Spira, Avrum, Gouon-Evans, Valerie, Murphy, George J, Mostoslavsky, Gustavo, Kotton, Darrell N

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The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF) by Xu, Feng, Tanabe, Naoya, Vasilescu, Dragos M., McDonough, John E., Coxson, Harvey O., Ikezoe, Kohei, Kinose, Daisuke, Ng, Kevin W., Verleden, Stijn E., Wuyts, Wim A., Vanaudenaerde, Bart M., Verschakelen, Johny, Cooper, Joel D., Lenburg, Marc E., Morshead, Katrina B., Abbas, Alexander R., Arron, Joseph R., Spira, Avrum, Hackett, Tillie-Louise, Colby, Thomas V., Ryerson, Christopher J., Ng, Raymond T., Hogg, James C.

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Discovering biological connections between experimental conditions based on common patterns of differential gene expression by Gower, Adam C, Spira, Avrum, Lenburg, Marc E

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Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors by Tagne, Jean-Bosco, Gupta, Sumeet, Gower, Adam C, Shen, Steven S, Varma, Saaket, Lakshminarayanan, Meenakshi, Cao, Yuxia, Spira, Avrum, Volkert, Thomas L, Ramirez, Maria I

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Transcription factor Klf4, induced in the lung by oxygen at birth, regulates perinatal fibroblast and myofibroblast differentiation by Jean, Jyh-Chang, George, Elizabeth, Kaestner, Klaus H, Brown, Lou Ann Scism, Spira, Avrum, Joyce-Brady, Martin

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The SERPINE2 Gene Is Associated with Chronic Obstructive Pulmonary Disease by DeMeo, Dawn L., Mariani, Thomas J., Lange, Christoph, Srisuma, Sorachai, Litonjua, Augusto A., Celedón, Juan C., Lake, Stephen L., Reilly, John J., Chapman, Harold A., Mecham, Brigham H., Haley, Kathleen J., Sylvia, Jody S., Sparrow, David, Spira, Avrum E., Beane, Jennifer, Pinto-Plata, Victor, Speizer, Frank E., Shapiro, Steven D., Weiss, Scott T., Silverman, Edwin K.

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Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer by Wang, Xuting, Chorley, Brian N, Pittman, Gary S, Kleeberger, Steven R, Brothers, 2nd, John, Liu, Gang, Spira, Avrum, Bell, Douglas A

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Identification of transforming growth factor-beta-regulated microRNAs and the microRNA-targetomes in primary lung fibroblasts by Ong, Jennie, Timens, Wim, Rajendran, Vijay, Algra, Arjan, Spira, Avrum, Lenburg, Marc E, Campbell, Joshua D, van den Berge, Maarten, Postma, Dirkje S, van den Berg, Anke, Kluiver, Joost, Brandsma, Corry-Anke

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A pharmacogenomic method for individualized prediction of drug sensitivity by Cohen, Adam L, Soldi, Raffaella, Zhang, Haiyu, Gustafson, Adam M, Wilcox, Ryan, Welm, Bryan E, Chang, Jeffrey T, Johnson, Evan, Spira, Avrum, Jeffrey, Stefanie S, Bild, Andrea H

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Summarizing performance for genome scale measurement of miRNA: reference samples and metrics by Pine, P Scott, Lund, Steven P, Parsons, Jerod R, Vang, Lindsay K, Mahabal, Ashish A, Cinquini, Luca, Kelly, Sean C, Kincaid, Heather, Crichton, Daniel J, Spira, Avrum, Liu, Gang, Gower, Adam C, Pass, Harvey I, Goparaju, Chandra, Dubinett, Steven M, Krysan, Kostyantyn, Stass, Sanford A, Kukuruga, Debra, Van Keuren-Jensen, Kendall, Courtright-Lim, Amanda, Thompson, Karol L, Rosenzweig, Barry A, Sorbara, Lynn, Srivastava, Sudhir, Salit, Marc L

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Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions by Maoz, Asaf, Merenstein, Carter, Koga, Yusuke, Potter, Austin, Gower, Adam C, Liu, Gang, Zhang, Sherry, Liu, Hanqiao, Stevenson, Christopher, Spira, Avrum, Reid, Mary E, Campbell, Joshua D, Mazzilli, Sarah A, Lenburg, Marc E, Beane, Jennifer

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Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers by Steiling, Katrina, Kadar, Aran Y, Bergerat, Agnes, Flanigon, James, Sridhar, Sriram, Shah, Vishal, Ahmad, Q Rushdy, Brody, Jerome S, Lenburg, Marc E, Steffen, Martin, Spira, Avrum

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The Shifting Landscape for Lung Cancer: Past, Present, and Future by Vachani, Anil, Sequist, Lecia V, Spira, Avrum

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Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy by Sofer, Tamar, Li, Ruitong, Joehanes, Roby, Lin, Honghuang, Gower, Adam C., Wang, Heming, Kurniansyah, Nuzulul, Cade, Brian E., Lee, Jiwon, Williams, Stephanie, Mehra, Reena, Patel, Sanjay R., Quan, Stuart F., Liu, Yongmei, Rotter, Jerome I., Rich, Stephen S., Spira, Avrum, Levy, Daniel, Gharib, Sina A., Redline, Susan, Gottlieb, Daniel J.

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