Monosomic loss of MIR15A/MIR16-1 is a driver of multiple myeloma proliferation and disease progression by Chesi, Marta, Stein, Caleb K, Garbitt, Victoria M, Sharik, Meaghen E, Asmann, Yan W, Bergsagel, Matteo, Riggs, Daniel L, Welsh, Seth J, Meermeier, Erin W, Kumar, Shaji K, Braggio, Esteban, Bergsagel, P Leif

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Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression by Calcinotto, Arianna, Brevi, Arianna, Chesi, Marta, Ferrarese, Roberto, Garcia Perez, Laura, Grioni, Matteo, Kumar, Shaji, Garbitt, Victoria M., Sharik, Meaghen E., Henderson, Kimberly J., Tonon, Giovanni, Tomura, Michio, Miwa, Yoshihiro, Esplugues, Enric, Flavell, Richard A., Huber, Samuel, Canducci, Filippo, Rajkumar, Vincent S., Bergsagel, P. Leif, Bellone, Matteo

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Exploiting the Gut Microbiota to Boost Immunotherapy and Switch the Trajectory of Multiple Myeloma by Cogrossi, Laura Lucia, Grioni, Matteo, Zordan, Paola, Mattorre, Benedetta, Lorenzoni, Marco, Meregalli, Greta, Policastro, Anna, Ferrarese, Roberto, Clementi, Nicola, Sisti, Sofia, Mancini, Nicasio, Chesi, Marta, Bergsagel, P. Leif, Bellone, Matteo

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P-384 Exploiting fiber-rich diet to perturb the microbiota-immune axis and thwart multiple myeloma progression by Cogrossi, Laura Lucia, Policastro, Anna, Grion, Matteo, Sisti, Sofia, Chesi, Marta, Bergsagel, Leif, Clementi, Nicola, Matteo, Bellone

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A High-Fiber Dietary Intervention (NUTRIVENTION) in Precursor Plasma Cell Disorders Improves Biomarkers of Disease and May Delay Progression to Myeloma by Shah, Urvi A., Cogrossi, Laura Lucia, Derkach, Andriy, Castro, Francesca, Fei, Teng, DeWolf, Susan, Garces, Juan-Jose, Policastro, Anna, Grioni, Matteo, Sisti, Sofia, Jenna, Blaslov, Adintori, Peter, Hosszu, Kinga K., McAvoy, Devin, Baichoo, Mirae, Cross, Justin, Anuraj, Aishwarya, Pohl, Charlotte, Ramos, Ruben, Sanchez, Jenny Paredes, Gipson, Brianna, Maclachlan, Kylee H, Gradissimo, Ana, Boiocchi, Leonardo, Koche, Richard, Chaligne, Ronan, Block, Torin, Korde, Neha, Tan, Carlyn Rose, Hultcrantz, Malin, Hassoun, Hani, Shah, Gunjan L., Scordo, Michael, Lahoud, Oscar B, Chung, David J., Landau, Heather J., Peled, Jonathan U., Clementi, Nicola, Chesi, Marta, Bergsagel, P. Leif, Mailankody, Sham, Pollak, Michael, D'Souza, Anita, Landgren, Ola, Chimonas, Susan, Giralt, Sergio, Usmani, Saad Z., Iyengar, Neil M., Lesokhin, Alexander M., Bellone, Matteo, van den Brink, Marcel R.M.

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OA-01 Exploiting microbiota commensals to potentiate immunotherapy and delay multiple myeloma evolution by Cogrossi, Laura Lucia, Ferrarese, Roberto, Grioni, Matteo, Zordan, Paola, Mattorre, Benedetta, Lorenzoni, Marco, Meregalli, Greta, Policastro, Anna, Sisti, Sofia, Brevi, Arianna, Chesi, Marta, Bergsagel, Leif, Clementi, Nicola, Mancini, Nicasio, Matteo, Bellone

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Chromogranin A Is Preferentially Cleaved into Proangiogenic Peptides in the Bone Marrow of Multiple Myeloma Patients by Bianco, Mimma, Gasparri, Anna Maria, Colombo, Barbara, Curnis, Flavio, Girlanda, Stefania, Ponzoni, Maurilio, Bertilaccio, Maria Teresa Sabrina, Calcinotto, Arianna, Sacchi, Angelina, Ferrero, Elisabetta, Ferrarini, Marina, Chesi, Marta, Bergsagel, P Leif, Bellone, Matteo, Tonon, Giovanni, Ciceri, Fabio, Marcatti, Magda, Caligaris-Cappio, Federico, Corti, Angelo

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Modifications of the mouse bone marrow microenvironment favor angiogenesis and correlate with disease progression from asymptomatic to symptomatic multiple myeloma by Calcinotto, Arianna, Ponzoni, Maurilio, Ria, Roberto, Grioni, Matteo, Cattaneo, Elena, Villa, Isabella, Sabrina Bertilaccio, Maria Teresa, Chesi, Marta, Rubinacci, Alessandro, Tonon, Giovanni, Bergsagel, P Leif, Vacca, Angelo, Bellone, Matteo

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Abstract A83: Modifications of the bone marrow microenvironment in the transition from monoclonal gammopathy of undetermined significance to multiple myeloma in VkMYC mice by Calcinotto, Arianna, Grioni, Matteo, Bertilaccio, Maria Teresa Sabrina, Chesi, Marta, Bergsagel, Leif, Casorati, Giulia, Dellabona, Paolo, Bellone, Matteo

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Angiogenesis Associated with Alterations of the Bone Marrow Microenvironment Predicts Multiple Myeloma Progression to Symptomatic Disease in Mice and Humans by Calcinotto, Arianna, Ponzoni, Maurilio, Ria, Roberto, Grioni, Matteo, Cattaneo, Elena, Villa, Isabella, Bertilaccio, Maria Teresa Sabrina, Chesi, Marta, Rubinacci, Alessandro, Tonon, Giovanni, Bergsagel, Peter Leif, Vacca, Angelo, Bellone, Matteo

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Early Trafficking of Bone Marrow Derived-Endothelial Progenitor Cells Promotes Multiple Myeloma Progression by Moschetta, Michele, Mishima, Yuji, Kawano, Yawara, Aljawai, Yosra, Paiva, Bruno, Palomera, Luis, Calcinotto, Arianna, Christine, Unitt L., Sahin, Ilyas, Sacco, Antonio, Glavey, Siobhan, Reagan, Michaela R., Manier, Salomon, Bergsagel, Peter Leif, Chesi, Marta, Bellone, Matteo, Roccaro, Aldo M, Ghobrial, Irene M.

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