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A hydrophobic residue in position 15 of the rP2X3 receptor slows desensitization and reveals properties beneficial for pharmacological analysis and high-throughput screening
by
Hausmann, Ralf
,
Bahrenberg, Gregor
,
Kuhlmann, Daniel
,
Schumacher, Michaela
,
Braam, Ursula
,
Bieler, Dagmar
,
Schlusche, Ilka
,
Schmalzing, Günther
Published in
Neuropharmacology
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Neuropharmacology
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2',3' O Adenosine Triphosphate
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5 [[(1,2,3,4 Tetrahydro 1
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Adenosine Triphosphate - Metabolism
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Amino Acid Sequence
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Animals
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Calcium - Metabolism
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Calcium Imaging
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Cell Line, Tumor
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Desensitization
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Drug Screening
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High-Throughput Screening Assays
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Humans
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Hydrophobic And Hydrophilic Interactions
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Isoleucine
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Life Sciences & Biomedicine
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Mechanism Of Antagonism
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Membrane Potentials - Drug Effects
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Molecular Sequence Data
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