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MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia
by
Zhang, Xiaolu
,
Li, Bingnan
,
Yu, Jingya
,
Dahlström, Jenny
,
Tran, Anh Nhi
,
Björkhom, Magnus
,
Xu, Dawei
Published in
Annals of hematology
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The Telomerase Reverse Transcriptase (hTERT) gene is a direct target of the histone methyltransferase SMYD3
by
CHENG LIU
,
XIAOLEI FANG
,
ZHENG GE
,
JALINK, Marit
,
KYO, Satoru
,
BJÖRKHOLM, Magnus
,
GRUBER, Astrid
,
SJÖBERG, Jan
,
DAWEI XU
Published in
Cancer research (Chicago, Ill.)
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Annals Of Hematology
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Cancer Research
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Humans
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Life Sciences & Biomedicine
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Medicin Och Hälsovetenskap
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Oncology
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Telomerase - Genetics
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Acetylation
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Base Sequence
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Chromatin Immunoprecipitation
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Drug Resistance, Neoplasm - Genetics
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Flt3Itd
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Fms-Like Tyrosine Kinase 3 - Antagonists & Inhibitors
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Springer Nature
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