Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomise... by Murray Brunt, Adrian, Haviland, Joanne S, Wheatley, Duncan A, Sydenham, Mark A, Alhasso, Abdulla, Bloomfield, David J, Chan, Charlie, Churn, Mark, Cleator, Susan, Coles, Charlotte E, Goodman, Andrew, Harnett, Adrian, Hopwood, Penelope, Kirby, Anna M, Kirwan, Cliona C, Morris, Carolyn, Nabi, Zohal, Sawyer, Elinor, Somaiah, Navita, Stones, Liba, Syndikus, Isabel, Bliss, Judith M, Yarnold, John R, Alhasso, Abdulla, Armstrong, Anne, Bliss, Judith, Bloomfield, David, Bowen, Jo, Brunt, Murray, Chan, Charlie, Chantler, Hannah, Churn, Mark, Cleator, Susan, Coles, Charlotte, Donovan, Ellen, Goodman, Andy, Griffin, Susan, Haviland, Jo, Hopwood, Penny, Kirby, Anna, Kirk, Julie, Kirwan, Cliona, MacLennan, Marjory, Morris, Carolyn, Nabi, Zohal, Sawyer, Elinor, Sculphur, Mark, Sinclair, Judith, Somaiah, Navita, Stones, Liba, Sydenham, Mark, Syndikus, Isabel, Tremlett, Jean, Venables, Karen, Wheatley, Duncan, Yarnold, John

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Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials by Bradley, Rosie, Braybrooke, Jeremy, Gray, Richard, Hills, Robert, Liu, Zulian, Peto, Richard, Davies, Lucy, Dodwell, David, McGale, Paul, Pan, Hongchao, Taylor, Carolyn, Anderson, Stewart, Gelber, Richard, Gianni, Luca, Jacot, William, Joensuu, Heikki, Moreno-Aspitia, Alvaro, Piccart, Martine, Press, Michael, Romond, Edward, Slamon, Dennis, Suman, Vera, Berry, Richard, Boddington, Clare, Clarke, Mike, Davies, Christina, Duane, Fran, Evans, Vaughan, Gay, Jo, Gettins, Lucy, Godwin, Jon, James, Sam, Liu, Hui, MacKinnon, Elizabeth, Mannu, Gurdeep, McHugh, Theresa, Morris, Philip, Read, Simon, Straiton, Ewan, Wang, Yaochen, Crown, John, de Azambuja, Evandro, Delaloge, Suzette, Fung, Helena, Geyer, Charles, Spielmann, Marc, Valagussa, Pinuccia, Albain, Kathy, Arriagada, Rodrigo, Bartlett, John, Bergsten-Nordström, Elizabeth, Bliss, Judith, Brain, Etienne, Carey, Lisa, Coleman, Robert, Cuzick, Jack, Davidson, Nancy, Del Mastro, Lucia, Di Leo, Angelo, Dignam, James, Dowsett, Mitch, Ejlertsen, Bent, Francis, Prue, Gnant, Michael, Goetz, Matthew, Goodwin, Pam, Halpin-Murphy, Pat, Hayes, Dan, Hill, Catherine, Jagsi, Reshma, Janni, Wolfgang, Loibl, Sibylle, Mamounas, Eleftherios P, Martín, Miguel, Mukai, Hirofumi, Nekljudova, Valentina, Norton, Larry, Ohashi, Yasuo, Pierce, Lori, Poortmans, Philip, Raina, Vinod, Rea, Daniel, Regan, Meredith, Robertson, John, Rutgers, Emiel, Spanic, Tanja, Sparano, Joseph, Steger, Guenther, Tang, Gong, Toi, Masakazu, Tutt, Andrew, Viale, Giuseppe, Wang, Xiang, Whelan, Tim, Wilcken, Nicholas, Wolmark, Norman, Cameron, David, Bergh, Jonas, Pritchard, Kathleen I, Swain, Sandra M

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Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials by Asselain, Bernard, Barlow, William, Bergh, Jonas, Bergsten-Nordström, Elizabeth, Bliss, Judith, Boccardo, Francesco, Boddington, Clare, Bogaerts, Jan, Bradley, Rosie, Brain, Etienne, Braybrooke, Jeremy, Broet, Philippe, Bryant, John, Burrett, Julie, Cameron, David, Clarke, Mike, Coates, Alan, Coleman, Robert, Coombes, Raoul Charles, Correa, Candace, Costantino, Joe, Cuzick, Jack, Davidson, Nancy, Davies, Christina, Davies, Lucy, Di Leo, Angelo, Dodwell, David, Dowsett, Mitch, Evans, Vaughan, Ewertz, Marianne, Fisher, Bernard, Forbes, John, Ford, Leslie, Gazet, Jean-Claude, Gelber, Richard, Gettins, Lucy, Gianni, Luca, Gnant, Michael, Godwin, Jon, Goldhirsch, Aron, Goodwin, Pamela, Gray, Richard, Hill, Catherine, Ingle, James, Jagsi, Reshma, Jakesz, Raimund, James, Sam, Janni, Wolfgang, Liu, Hui, Liu, Zulian, Lohrisch, Caroline, Loibl, Sibylle, Mamounas, Eleftherios, Mannu, Gurdeep, Martín, Miguel, Mathoulin, Simone, Mauriac, Louis, McGale, Paul, Morris, Philip, Mukai, Hirofumi, Norton, Larry, Ohashi, Yasuo, Olivotto, Ivo, Paik, Soon, Peto, Richard, Piccart, Martine, Pierce, Lori, Poortmans, Philip, Powles, Trevor, Pritchard, Kathy, Ragaz, Joseph, Raina, Vinod, Ravdin, Peter, Read, Simon, Regan, Meredith, Robertson, John, Rutgers, Emiel, Scholl, Suzy, Slamon, Dennis, Sölkner, Lidija, Steinberg, Seth, Sutcliffe, Rosemary, Swain, Sandra, Taylor, Carolyn, Tutt, Andrew, Valagussa, Pinuccia, van de Velde, Cornelis, van der Hage, Jos, Viale, Giuseppe, von Minckwitz, Gunter, Wang, Yaochen, Wang, Zhe, Wang, Xiang, Whelan, Tim, Wilcken, Nicholas, Winer, Eric, Wolmark, Norman, Wood, William, Zambetti, Milvia, Zujewski, Jo Anne

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Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26... by Gray, Richard, Liu, Zulian, Peto, Richard, Davies, Lucy, McGale, Paul, Pan, Hongchao, Taylor, Carolyn, Barlow, William, Bliss, Judith, Bruzzi, Paolo, Cameron, David, Fountzilas, George, Loibl, Sibylle, Martin, Miguel, Möbus, Volker, Nekljudova, Valentina, De Placido, Sabino, Untch, Michael, Norton, Larry, Burrett, Julie, Evans, Vaughan, Hills, Robert, James, Sam, Mannu, Gurdeep, Morris, Philip, Wang, Yaochen, Wang, Zhe, Gnant, Michael, Di Leo, Angelo, Dolci, Stella, Larsimont, Denis, Nogaret, Jean Marie, Piccart, Martine, Linn, Sabine, Peer, Petronella, Tjan-Heijnen, Vivianne, Vliek, Sonja, Slamon, Dennis, Bramwell, Vivien H, Chen, Bingshu, Chia, Stephen, Gelmon, Karen, Goss, Paul, Parulekar, Wendy, Pater, Joseph, Rakovitch, Eileen, Shepherd, Lois, Berry, Don, Broadwater, Gloria, Shan, Yi, Xu, Binghe, Zhao, Dong-Bing, Bartelink, Harry, Cufer, Tanja, Poortmans, Philip, Rutgers, Emiel, van de Velde, Cornelis, Carrasco, Eva, Costa, Serban, Gerber, Bernd, Jackisch, Christian, von Minckwitz, Gunter, Giuliano, Mario, De Laurentiis, Michele, Bamia, Christina, Mavroudis, Dimitris, A'Hern, Roger, Sadoon, Mohammad, Costantino, Joe, Dignam, James, Fisher, Bernard, Mamounas, Eleftherios P, Paik, Soon, Redmond, Carol, Wickerham, D Lawrence, Venturini, Marco, Pastorino, Simona, Sertoli, Mario Roberto, Albain, Kathy, Arriagada, Rodrigo, Bergsten Nordström, Elizabeth, Boccardo, Francesco, Coleman, Robert, Correa, Candace, Dowsett, Mitch, Ewertz, Marianne, Goldhirsch, Aron, Hill, Catherine, Jagsi, Reshma, Janni, Wolfgang, Mukai, Hirofumi, Ohashi, Yasuo, Pierce, Lori, Raina, Vinod, Ravdin, Peter, Rea, Daniel, Sparano, Joseph, Tutt, Andrew, Viale, Giuseppe, Zambetti, Milvia

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Aromatase inhibitors versus tamoxifen in premenopausal women with oestrogen receptor-positive early-stage breast cancer treated with ovarian suppression: a patient-level meta-analy... by Bradley, Rosie, Braybrooke, Jeremy, Gray, Richard, Hills, Robert K, Liu, Zulian, Pan, Hongchao, Peto, Richard, Dodwell, David, McGale, Paul, Taylor, Carolyn, Francis, Prudence A, Gnant, Michael, Perrone, Francesco, Regan, Meredith M, Berry, Richard, Boddington, Clare, Clarke, Mike, Davies, Christina, Davies, Lucy, Duane, Fran, Evans, Vaughan, Gay, Jo, Gettins, Lucy, Godwin, Jon, James, Sam, Liu, Hui, MacKinnon, Elizabeth, Mannu, Gurdeep, McHugh, Theresa, Morris, Philip, Read, Simon, Straiton, Ewan, Jakesz, Raimund, Fesl, Christian, Pagani, Olivia, Gelber, Richard, De Laurentiis, Michelino, De Placido, Sabino, Gallo, Ciro, Albain, Kathy, Anderson, Stewart, Arriagada, Rodrigo, Bartlett, John, Bergsten-Nordström, Elizabeth, Bliss, Judith, Brain, Etienne, Carey, Lisa, Coleman, Robert, Cuzick, Jack, Davidson, Nancy, Del Mastro, Lucia, Di Leo, Angelo, Dignam, James, Dowsett, Mitch, Ejlertsen, Bent, Goetz, Matthew, Goodwin, Pam, Halpin-Murphy, Pat, Hayes, Dan, Hill, Catherine, Jagsi, Reshma, Janni, Wolfgang, Loibl, Sibylle, Mamounas, Eleftherios P, Martín, Miguel, Mukai, Hirofumi, Nekljudova, Valentina, Norton, Larry, Ohashi, Yasuo, Pierce, Lori, Poortmans, Philip, Pritchard, Kathleen I, Raina, Vinod, Rea, Daniel, Robertson, John, Rutgers, Emiel, Spanic, Tanja, Sparano, Joseph, Steger, Guenther, Tang, Gong, Toi, Masakazu, Tutt, Andrew, Viale, Giuseppe, Wang, Xiang, Whelan, Tim, Wilcken, Nicholas, Wolmark, Norman, Cameron, David, Bergh, Jonas, Swain, Sandra M

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Radiotherapy to regional nodes in early breast cancer: an individual patient data meta-analysis of 14 324 women in 16 trials by Taylor, Carolyn, Dodwell, David, McGale, Paul, Hills, Robert K, Berry, Richard, Bradley, Rosie, Braybrooke, Jeremy, Clarke, Mike, Gray, Richard, Holt, Francesca, Liu, Zulian, Pan, Hongchao, Peto, Richard, Straiton, Ewan, Coles, Charlotte, Duane, Fran, Hennequin, Christophe, Jones, Glenn, Kühn, Thorsten, Oliveros, Sileida, Overgaard, Jens, Pritchard, Kathy I, Suh, Chang-Ok, Beake, Graham, Boddington, Clare, Davies, Christina, Davies, Lucy, Evans, Vaughan, Gay, Jo, Gettins, Lucy, Godwin, Jon, James, Sam, Kerr, Amanda, Liu, Hui, MacKinnon, Elizabeth, Mannu, Gurdeep, McHugh, Theresa, Morris, Philip, Nakahara, Mariko, Read, Simon, Taylor, Hannah, Ferguson, John, Scheurlen, Hans, Zurrida, Stefano, Galimberti, Viviana, Ingle, James, Valagussa, Pinuccia, Veronesi, Umberto, Anderson, Stewart, Tang, Gong, Fisher, Bernard, Fossa, Sophie, Valborg Reinertsen, Kristin, Host, Herman, Muss, Hyman, Holli, Kaija, Albain, Kathy, Arriagada, Rodrigo, Bartlett, John, Bergsten-Nordström, Elizabeth, Bliss, Judith, Brain, Etienne, Carey, Lisa, Coleman, Robert, Cuzick, Jack, Davidson, Nancy, Del Mastro, Lucia, Di Leo, Angelo, Dignam, James, Dowsett, Mitch, Ejlertsen, Bent, Francis, Prue, García-Sáenz, José Angel, Gelber, Rich, Gnant, Michael, Goetz, Matthew, Goodwin, Pam, Halpin-Murphy, Pat, Hayes, Dan, Hill, Catherine, Jagsi, Reshma, Janni, Wolfgang, Loibl, Sibylle, Mamounas, Eleftherios, Martín, Miguel, McIntosh, Stuart, Mukai, Hirofumi, Nekljudova, Valentina, Norton, Larry, Ohashi, Yasuo, Piccart, Martine, Pierce, Lori, Raina, Vinod, Rea, Daniel, Regan, Meredith, Robertson, John, Rutgers, Emiel, Salgado, Roberto, Slamon, Dennis, Spanic, Tanja

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Quantifying the carbon footprint of clinical trials: guidance development and case studies by Griffiths, Jessica, Fox, Lisa, Williamson, Paula R, Adshead, Fiona, Salman, Rustam Al-Shahi, Anderson, Craig, Bedson, Emma, Bliss, Judith, Boshoff, Ana, Chen, Xiaoying, Cranley, Denise, Doran, Peter, Gamble, Carrol, Hood, Kerenza, McGregor, Naomi, McNamara, Carolyn, Midha, Elis, Moore, Keith, Perkins, Alexis M, Pett, Sarah, Sydes, Matthew R

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POSNOC—POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy: a randomised controlled trial of axillary treatment in women... by Goyal, Amit, Mann, G Bruce, Fallowfield, Lesley, Duley, Lelia, Reed, Malcolm, Dodwell, David, Coleman, Robert E, Fakis, Apostolos, Newcombe, Robert, Jenkins, Valerie, Whitham, Diane, Childs, Margaret, Whynes, David, Keeley, Vaughan, Ellis, Ian, Fairbrother, Patricia, Sadiq, Shabina, Monson, Kathryn, Montgomery, Alan, Tan, Wei, Vale, Luke, Homer, Tara, Badger, Heath, Haines, Rachel Helen, Lewis, Mickey, Megias, Daniel, Nabi, Zohal, Singh, Preetinder, Caraman, Andrei, Miles, Elizabeth, Mir, Romaana, Davis, Daniel, Grieve, Teresa, Mitchell, Eleanor, Haydock, Rebecca, Brittain, Clare, Upton, Clare, Craig, Sarah, Shafayat, Aisha, Gidman, Charlotte, Ozolins, Mara, Ternent, Laura, Francis, Nicole, Probert, Flonda, Paksec, Lisa, Lucas, Rose, Dempsey, Annette, Thornton, Rochelle, Butt, Roeum, Price, Hannah, Thompson, Alastair, Ring, Alistair, Sharma, Nisha, Lee, Peter Barrett, Wolfarth, Julie, White, Ian, Cutress, Ramsey, Bliss, Judith, Rea, Daniel, Dubsky, Peter

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The Lancet Breast Cancer Commission: tackling a global health, gender, and equity challenge by Coles, Charlotte Elizabeth, Anderson, Benjamin O, Cameron, David, Cardoso, Fatima, Horton, Richard, Knaul, Felicia Marie, Mutebi, Miriam, Lee, Naomi, Abraham, Jean E, Anderson, Benjamin O, André, Fabrice, Barrios, Carlos H, Bliss, Judith M, Boughey, Judy C, Cameron, David A, Cardoso, Fatima V, Carey, Lisa A, Chatterjee, Sanjoy, Coles, Charlotte E, Cuzick, Jack, Du Plooy, Dorothy, Francis, Prudence A, Gralow, Julie R, Jagsi, Reshma, Knaul, Felicia M, Ma, Fei, Mann, Ritse M, McIntosh, Stuart A, Mertz, Shirley A, Mutebi, Miriam, Olopade, Funmi, Phillips, Kelly-Anne, Poortmans, Philip M, Spanic, Tanja, Spence, Dingle, Stobart, Hilary, Symmans, Fraser WF, Villarreal-Garza, Cynthia, Yip, Cheng-Har, Bienz, Maya J, Drewett, Lynsey M, Fulton, Alex, Inbah Rajah, Dharrnesha, Kazmi, Farasat, Rubasingham, Jeffrey, Thompson, Mareike, Vargas, Valentina, Arreola, Hector, Badwe, Raj A, Calderon Anyosa, Renzo JC, Dave, Rajiv V, De-Graft Aikins, Ama, Earl, Helena M, Essue, Beverley M, Etzioni, Ruth B, Hawley, Sarah T, Jiang, Xiaoxiao, Mittra, Indraneel, Moreno, Patricia I, Nargund, Renu Sara, Noble, Cara, Smith, Robert A, Verhoeven, Didier, Wang, Jiani N, Watkins, David A, Zikmund-Fisher, Brian J

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Large breast size as a risk factor for late adverse effects of breast radiotherapy: Is residual dose inhomogeneity, despite 3D treatment planning and delivery, the main explanation... by Goldsmith, Christy, Haviland, Joanne, Tsang, Yat, Sydenham, Mark, Yarnold, John

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A Randomised Phase 2 Trial of Intensive Induction Chemotherapy (CBOP/BEP) and Standard BEP in Poor-prognosis Germ Cell Tumours (MRC TE23, CRUK 05/014, ISRCTN 53643604) by Huddart, Robert A, Gabe, Rhian, Cafferty, Fay H, Pollock, Philip, White, Jeff D, Shamash, Jonathan, Cullen, Michael H, Stenning, Sally P

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Clinical impact of IMPORT HIGH trial (CRUK/06/003) on breast radiotherapy practices in the United Kingdom by Tsang, Yat, Ciurlionis, Laura, Kirby, Anna M, Locke, Imogen, Venables, Karen, Yarnold, John R, Titley, Jenny, Bliss, Judith, Coles, Charlotte E

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The impact of dose heterogeneity on late normal tissue complication risk after hypofractionated whole breast radiotherapy by Tsang, Yat, Haviland, Joanne, Venables, Karen, Yarnold, John

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Dosimetry and field matching for radiotherapy to the breast and supraclavicular fossa by Miles, Elizabeth A, Venables, Karen, Hoskin, Peter J, Aird, Edwin G.A

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Quality assurance analysis of participating centres' protocol compliance to a UK multicentre hypofractionated breast (FAST) trial by Tsang, Y, Venables, K, Yarnold, J

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Readers' Dialogue by Rule, Ann M., Strunk, Ann M., Parsons, Harol Deane, Voolich, Erica, Piatt, Diana L., Bell, Karen M., Phillips, Guy B., Partner, Bruce E., Partner, Sue A., Sipka, Timothy A., Mullenex, James D., Bliss, Judith S.

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The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised con... by Haviland, Joanne S, MSc, Owen, J Roger, FRCR, Dewar, John A, Prof, Agrawal, Rajiv K, FRCR, Barrett, Jane, FRCR, Barrett-Lee, Peter J, Prof, Dobbs, H Jane, FRCR, Hopwood, Penelope, MD, Lawton, Pat A, PhD, Magee, Brian J, FRCR, Mills, Judith, MPhil, Simmons, Sandra, Sydenham, Mark A, BSc, Venables, Karen, PhD, Bliss, Judith M, Prof, Yarnold, John R, Prof

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Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer by O’Leary, Ben, Hrebien, Sarah, Morden, James P., Beaney, Matthew, Fribbens, Charlotte, Huang, Xin, Liu, Yuan, Bartlett, Cynthia Huang, Koehler, Maria, Cristofanilli, Massimo, Garcia-Murillas, Isaac, Bliss, Judith M., Turner, Nicholas C.

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Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer by Chopra, Neha, Tovey, Holly, Pearson, Alex, Cutts, Ros, Toms, Christy, Proszek, Paula, Hubank, Michael, Dowsett, Mitch, Dodson, Andrew, Daley, Frances, Kriplani, Divya, Gevensleben, Heidi, Davies, Helen Ruth, Degasperi, Andrea, Roylance, Rebecca, Chan, Stephen, Tutt, Andrew, Skene, Anthony, Evans, Abigail, Bliss, Judith M., Nik-Zainal, Serena, Turner, Nicholas C.

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Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled... by Coles, Charlotte E, Griffin, Clare L, Kirby, Anna M, Titley, Jenny, Agrawal, Rajiv K, Alhasso, Abdulla, Bhattacharya, Indrani S, Brunt, Adrian M, Ciurlionis, Laura, Chan, Charlie, Donovan, Ellen M, Emson, Marie A, Harnett, Adrian N, Haviland, Joanne S, Hopwood, Penelope, Jefford, Monica L, Kaggwa, Ronald, Sawyer, Elinor J, Syndikus, Isabel, Tsang, Yat M, Wheatley, Duncan A, Wilcox, Maggie, Yarnold, John R, Bliss, Judith M, Al Sarakbi, Wail, Barber, Sarah, Barnett, Gillian, Bliss, Peter, Dewar, John, Eaton, David, Ebbs, Stephen, Ellis, Ian, Evans, Philip, Harris, Emma, James, Hayley, Kirwan, Cliona, Kirk, Julie, Mayles, Helen, McIntyre, Anne, Mills, Judith, Poynter, Andrew, Provenzano, Elena, Rawlings, Christine, Sculpher, Mark, Sumo, Georges, Sydenham, Mark, Tutt, Andrew, Twyman, Nicola, Venables, Karen, Winship, Anna, Winstanley, John, Wishart, Gordon, Thompson, Alastair

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