Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus by Sullivan, B A, Tsuji, W, Kivitz, A, Peng, J, Arnold, G E, Boedigheimer, M J, Chiu, K, Green, C L, Kaliyaperumal, A, Wang, C, Ferbas, J, Chung, J B

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2184 A phase 2 study of mechanisms of acquired resistance to panitumumab (pmab) plus irinotecan (iri) for metastatic colorectal cancer (mCRC) by Siena, S, Sartore-Bianchi, A, Karthaus, M, Smith, D, Garcia-Carbonero, R, Van Cutsem, E, Guan, X, Boedigheimer, M, Sidhu, R, Jung, A.S, Oliner, K.S, Tabernero, J, Bardelli, A

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Chondro/osteoblastic and cardiovascular gene modulation in human artery smooth muscle cells that calcify in the presence of phosphate and calcitriol or paricalcitol by Shalhoub, V., Shatzen, E.M., Ward, S.C., Young, J-I., Boedigheimer, M., Twehues, L., McNinch, J., Scully, S., Twomey, B., Baker, D., Kiaei, P., Damore, M.A., Pan, Z., Haas, K., Martin, D.

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Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation by Östling, Jörgen, Ax, Elisabeth, Calvén, Jenny, Thörn, Kristofer, Israelsson, Elisabeth, Öberg, Lisa, Wilson, Susan J., Ward, Jonathan A., Chauhan, Anoop, Sousa, Ana R., De Meulder, Bertrand, Baribaud, Frédéric, Sterk, Peter J., Guo, Yike, Dahlen, Barbro, Chanez, Pascal, Shaw, Dominick E., Krug, Norbert, Hohlfeld, Jens M., Sandström, Thomas, James, Anna, Hinks, Timothy S.C., Howarth, Peter H., Vaarala, Outi, van Geest, Marleen, Olsson, Henric, Ahmed, H., Auffray, C., Bakke, P., Bansal, A.T., Bates, S., Bel, E.H., Bigler, J., Boedigheimer, M.J., Bønnelykke, K., Brandsma, J., Bucchioni, E., Bush, A., Caruso, M., Chaiboonchoe, A., Chanez, P., Chung, F.K., Corfield, J., D'Amico, A., De Meulder, B., Djukanovic, R., Fichtner, K., Fleming, L.J., Formaggio, E., Frey, U., Goss, V., Guo, Y., Hashimoto, S., Haughney, J., Hekking, P.W., Higenbottam, T., Hohlfeld, J.M., Holweg, C., Horváth, I., James, A.J., Knowles, R., Loza, M.J., Manta, A., Matthews, J.G., Mazein, A., Meiser, A., Middelveld, R.J.M., Miralpeix, M., Montuschi, P., Murray, C.S., Myles, D., Pahus, L., Pandis, I., Pavlidis, S., Postle, A., Powel, P., Praticò, G., Riley, J., Roberts, G., Rowe, A., Sandström, T., Schofield, J.P.R., Selby, A., Shaw, D.E., Sigmund, R., Singer, F., Skipp, P.J., Sousa, A.R., Sterk, P.J., Sun, K., Thornton, B., van Aalderen, W.M., van Geest, M., Vestbo, J., Vissing, N.H., Wagener, A.H., Wagers, S.S., Weiszhart, Z., Wheelock, C.E., Wilson, S.J.

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IL-17–high asthma with features of a psoriasis immunophenotype by Schofield, James P.R., Ward, Jonathan, Montuschi, Paolo, Auffray, Charles, Adcock, Ian M., Howarth, Peter, Vaarala, Outi, Bates, S., Bigler, J., Boedigheimer, M.J., Bønnelykke, K., Bucchioni, E., Burg, D., Compton, C.H., Corfield, J., D'Amico, A., Dahlen, S.E., Fichtner, K., Fitch, N., Fowler, S.J., Frey, U., Gahlemann, M., Hashimoto, S., Hedlin, G., Knox, A.J., Lutter, R., Middelveld, R.J.M., Mores, N., Myles, D., Pavlidis, S., Rao, M. Puig N., Rowe, A., Sandström, T., Sigmund, R., Singer, F., Sousa, A.R., Sun, K., Thornton, B., van Aalderen, W.M., Vestbo, J., Wilson, S.J., Badorrek, P., Barber, Clair, Batuwitage, Manohara Kanangana, Berton, A., Bochenek, Grazyna, Dahlén, B., De Alba, Jorge, Dekker, Tamara, Dennison, P., Dodson, Paul, Edwards, Jessica, Emma, Rosalia, Flood, Breda, Guillmant-Farry, E., Hewitt, Lorraine, Hu, X., Johnson, K., Klüglich, M., Kots, Maxim, Kuo, Scott, Lambrecht, Bart, Lantz, A.-S., Latzin, P., Lemonnier, N., Lone-Latif, Saeeda, Manta, Alexander, Martin, Jane, Metcalf, Leanne, Mikus, Maria, Monk, Philip, Nething, K., Nicholas, Ben, Niven, R., Nordlund, B., Nsubuga, S., Palkonen, Susanna, Pellet, J., Pennazza, Giorgio, Petrén, Anne, Pink, Sandy, Rahman-Amin, Malayka, Reynolds, Leanne, Robberechts, Martine, Russell, Kirsty, Rutgers, Michael, Santini, G., Saqi, M., Scott, S., Smith, Katherine M., Stephan, S., Strandberg, K., Szentkereszty, M., Tariq, K., Thorsen, Jonathan, van Drunen, C.M., Wetzel, Kristiane, Wiegman, Coen, Yeyasingham, Elizabeth, Zetterquist, W.

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Calcification inhibitors and Wnt signaling proteins are implicated in bovine artery smooth muscle cell calcification in the presence of phosphate and vitamin D sterols by Shalhoub, V, Shatzen, E, Henley, C, Boedigheimer, M, McNinch, J, Manoukian, R, Damore, M, Fitzpatrick, D, Haas, K, Twomey, B, Kiaei, P, Ward, S, Lacey, D L, Martin, D

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Pathway discovery using transcriptomic profiles in adult-onset severe asthma by Hekking, Pieter-Paul, Loza, Matt J., Pavlidis, Stelios, de Meulder, Bertrand, Lefaudeux, Diane, Baribaud, Fred, Auffray, Charles, Brinkman, Paul, Lutter, Rene, Bansal, Aruna T., Sousa, Ana R., Bates, Steve A., Pandis, Yannis, Fleming, Louise J., Shaw, Dominique E., Fowler, Stephen J., Meiser, Andrea, Sun, Kai, Corfield, Julie, Howarth, Peter H., Bel, Elisabeth H., Adcock, Ian M., Chung, Kian Fan, Djukanovic, Ratko, Adcock, I.M., Auffray, C., Bakke, P., Bansal, A.T., Baribaud, F., Bates, S., Bel, E.H., Bigler, J., Bisgaard, H., Boedigheimer, M.J., Bønnelykke, K., Brandsma, J., Bucchioni, E., Burg, D., Caruso, M., Chanez, P., Chung, F.K., Compton, C.H., Corfield, J., D'Amico, A., Dahlen, S.E., De Meulder, B., Erpenbeck, V.J., Erzen, D., Fichtner, K., Fitch, N., Formaggio, E., Frey, U., Gahlemann, M., Geiser, T., Hashimoto, S., Haughney, J., Hedlin, G., Hohlfeld, J.M., Holweg, C., Horváth, I., Howarth, P., Knowles, R., Krug, N., Lefaudeux, D., Loza, M.J., Lutter, R., Manta, A., Matthews, J.G., Mazein, A., Middelveld, R.J.M., Mores, N., Myles, D., Pahus, L., Pandis, I., Pavlidis, S., Powel, P., Praticò, G., Valls, M Puig, Rao, N., Riley, J., Roberts, G., Rowe, A., Sandström, T., Seibold, W., Selby, A., Sigmund, R., Singer, F., Skipp, P.J., Sousa, A.R., Sterk, P.J., Sun, K., Thornton, B., van Geest, M., Vestbo, J., Vissing, N.H., Wagener, A.H., Wagers, S.S., Weiszhart, Z., Wheelock, C.E., Wilson, S.J.

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Stratification of asthma phenotypes by airway proteomic signatures by Burg, Dominic, Nicholas, Ben, Strazzeri, Fabio, Staykova, Doroteya, Bansal, Aruna T., Xian, Yang, Corfield, Julie, Wilson, Susan, Ward, Jonathan, Lutter, Rene, Shaw, Dominick E., Bakke, Per S., Caruso, Massimo, Dahlen, Sven-Erik, Fowler, Stephen J., Horváth, Ildikó, Howarth, Peter, Krug, Norbert, Montuschi, Paolo, Sandström, Thomas, Sun, Kai, Riley, John, Auffray, Charles, De Meulder, Bertrand, Lefaudeux, Diane, Sterk, Peter J., Djukanović, Ratko, Ahmed, H., Badorrek, P., Ballereau, S., Baribaud, F., Behndig, A.F., Berglind, A., Berton, A., Bigler, J., Boedigheimer, M.J., Bønnelykke, K., Brinkman, P., Bush, A., Casaulta, C., Chaiboonchoe, A., Davison, T., De Meulder, B., Delin, I., El Hadjam, L., Erzen, D., Faulenbach, C., Fitch, N., Formaggio, E., Gahlemann, M., Garissi, D., Garret, T., Gent, J., Guillmant-Farry, E., Henriksson, E., James, A., Johnson, K., Jullian, N., Kerry, G., Klüglich, M., Knowles, R., Konradsen, J.R., Kretsos, K., Lantz, A.-S., Larminie, C., Latzin, P., Lefaudeux, D., Lemonnier, N., Lowe, L.A., Lutter, R., Mazein, A., McEvoy, L., Mores, N., Murray, C.S., Nething, K., Nordlund, B., Nsubuga, S., Pellet, J., Pison, C., Praticò, G., Valls, M. Puig, Rossios, C., Santini, G., Saqi, M., Sehgal, N., Söderman, P., Sogbesan, A., Spycher, F., Stephan, S., Stokholm, J., Sunther, M., Szentkereszty, M., Tamasi, L., Valente, S., van Aalderen, W.M., van Drunen, C.M., Van Eyll, J., Vyas, A., Yu, W., Zwinderman, A.H.

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Haemophilus influenzae and Moraxella catarrhalis in sputum of severe asthma with inflammasome and neutrophil activation by Versi, Ali, Ivan, Fransiskus Xaverius, Abdel-Aziz, Mahmoud I, Bates, Stewart, Riley, John, Baribaud, Frederic, Kermani, Nazanin Zounemat, Montuschi, Paolo, Dahlen, Sven-Erik, Djukanovic, Ratko, Sterk, Peter, Maitland-Van Der Zee, Anke H, Chotirmall, Sanjay H, Howarth, Peter, Adcock, Ian M, Chung, Kian Fan

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Treatable traits in the European U‐BIOPRED adult asthma cohorts by Simpson, Andrew J., Hekking, Pieter‐Paul, Shaw, Dominick E., Fleming, Louise J., Roberts, Graham, Riley, John H., Bates, Stewart, Sousa, Ana R., Bansal, Aruna T., Pandis, Ioannis, Sun, Kai, Bakke, Per S., Caruso, Massimo, Dahlén, Barbro, Dahlén, Sven‐Erik, Horvath, Ildiko, Krug, Norbert, Montuschi, Paolo, Sandstrom, Thomas, Singer, Florian, Adcock, Ian M., Wagers, Scott S., Djukanovic, Ratko, Chung, Kian Fan, Sterk, Peter J., Fowler, Stephen J., Ahmed, H, Auffray, C, Baribaud, F, Bel, E. H, Bisgaard, H, Bønnelykke, K, Brandsma, J, Brinkman, P, Bucchioni, E, Burg, D, Bush, A, Chaiboonchoe, A, Chanez, P, Compton, C. H, Corfield, J, D'Amico, A, De Meulder, B, Erpenbeck, V. J, Erzen, D, Fichtner, K, Fleming, L. J, Formaggio, E, Frey, U, Gahlemann, M, Geiser, T, Goss, V, Guo, Y, Hashimoto, S, Haughney, J, Hedlin, G, Hekking, P. W, Higenbottam, T, Hohlfeld, J. M, Holweg, C, Horváth, I, Howarth, P, James, A. J, Knowles, R, Knox, A. J, Lefaudeux, D, Lutter, R, Manta, A, Masefield, S, Matthews, J. G, Mazein, A, Meiser, A, Middelveld, R. J. M, Miralpeix, M, Mores, N, Murray, C. S, Myles, D, Pahus, L, Pavlidis, S, Postle, A, Powel, P, Praticò, G, Rao, N, Roberts, A, Roberts, G, Rowe, A, Sandström, T, Schofield, J. P. R, Selby, A, Sigmund, R, Skipp, P. J, Thornton, B, Aalderen, W. M, Geest, M, Vestbo, J, Vissing, N. H, Wagener, A. H, Weiszhart, Z, Wheelock, C. E, Wilson, S. J

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Asthma similarities across ProAR (Brazil) and U-BIOPRED (Europe) adult cohorts of contrasting locations, ethnicity and socioeconomic status by Cruz, Alvaro A., Riley, John H., Bansal, Aruna T., Souza-Machado, Adelmir, Almeida, Paula C.A., Biao-Lima, Valmar, Bates, Stewart, Adcock, Ian M., Sterk, Peter J., Araujo, M.I., Barnes, K.C., Belitardo, E., Bião-Lima, V., Cardoso, L., Camargos, P.A., Chatkin, J.M., Costa, R.S., Coelho, A.C.C., Cooper, P.J., Cruz, A.A., Cruz, C.S., Cunha, J., de Jesus, J.V., Gomes-Filho, I., Lima-Matos, A., Figueiredo, C.A., Lessa, M.A., Muniz, I.S., Pinheiro, G.P., Ponte, E.V., Santana, C.V.N., Santos-Lima, G., Souza, T.M.O., Souza-Machado, A., Stelmach, R., Vasquez, V.S., Adcock, I.M., Ahmed, H., Bakke, P., Baribaud, F., Bel, E.H., Bigler, J., Boedigheimer, M.J., Bønnelykke, K., Brinkman, P., Bucchioni, E., Caruso, M., Chaiboonchoe, A., Chanez, P., Compton, C.H., D'Amico, A., Dahlén, S.E., De Meulder, B., Djukanovic, R., Erpenbeck, V.J., Fichtner, K., Fitch, N., Fleming, L.J., Formaggio, E., Frey, U., Gahlemann, M., Goss, V., Hedlin, G., Hekking, P.W., Higenbottam, T., Hohlfeld, J.M., Holweg, C., James, A.J., Knox, A.J., Krug, N., Lefaudeux, D., Loza, M.J., Lutter, R., Manta, A., Masefield, S., Matthews, J.G., Middelveld, R.J.M., Montuschi, P., Myles, D., Pahus, L., Pandis, I., Pavlidis, S., Powel, P., Puig Valls, M., Rao, N., Roberts, G., Rowe, A., Sandström, T., Schofield, J.P.R., Selby, A., Shaw, D.E., Sigmund, R., Singer, F., Sun, K., Thornton, B., van Aalderen, W.M., Wagener, A.H., Wagers, S.S., Weiszhart, Z., Wilson, S.J.

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Urinary Leukotriene E 4 and Prostaglandin D 2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study by Kolmert, Johan, Gómez, Cristina, Balgoma, David, Sjödin, Marcus, Bood, Johan, Konradsen, Jon R, Ericsson, Magnus, Thörngren, John-Olof, James, Anna, Mikus, Maria, Sousa, Ana R, Riley, John H, Bates, Stewart, Bakke, Per S, Pandis, Ioannis, Caruso, Massimo, Chanez, Pascal, Fowler, Stephen J, Geiser, Thomas, Howarth, Peter, Horváth, Ildikó, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Behndig, Annelie, Shaw, Dominick E, Knowles, Richard G, Holweg, Cécile T J, Wheelock, Åsa M, Dahlén, Barbro, Nordlund, Björn, Alving, Kjell, Hedlin, Gunilla, Chung, Kian Fan, Adcock, Ian M, Sterk, Peter J, Djukanovic, Ratko, Dahlén, Sven-Erik, Wheelock, Craig E

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B21 TRANSLATIONAL ASTHMA RESEARCH: Transcriptomic Fingerprints In Peripheral Blood From The Adult Cohort Of The U-Biopred Study by Bigler, J, Boedigheimer, M, Rowe, A, Twehues, L, Chung, K, Djukanovic, R, Sousa, A R, Corfield, J, Adcock, I M, Welcher, A, Sterk, P J

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Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers by Brandsma, Joost, Goss, Victoria M., Yang, Xian, Bakke, Per S., Caruso, Massimo, Chanez, Pascal, Dahlén, Sven-Erik, Fowler, Stephen J., Horvath, Ildiko, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Sandström, Thomas, Shaw, Dominick E., Chung, Kian Fan, Singer, Florian, Fleming, Louise J., Sousa, Ana R., Pandis, Ioannis, Bansal, Aruna T., Sterk, Peter J., Djukanović, Ratko, Postle, Anthony D.

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A21 GENETIC REGULATION OF CHRONIC AIRWAY INFLAMMATION: Molecular Biomarkers Of Atopic Asthma In Blood And Sputum by Bigler, J, Boedigheimer, M, Farnsworth, C, Timour, M, O'Byrne, P M, Gauvreau, G M, Boulet, L, Cockcroft, D W, Fitzgerald, J M, Davis, B E, Leigh, R, Parnes, J, Russell, C B

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C30 LATE BREAKING ABSTRACTS IN DISEASE TREATMENT AND CLINICAL OUTCOMES: Effects Of Amg 157, An Anti-Thymic Stromal Lymphopoietin Monoclonal Antibody, On Allergen-Induced Early And... by Gauvreau, G M, O'Byrne, P M, Boulet, L-P, Wang, D, Cockcroft, D W, Bigler, J, FitzGerald, J M, Boedigheimer, M, Davis, B E, Dias, C, Gorski, K, Smith, L, Bautista, E, Leigh, R, Parnes, J R

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Gene Expression Profiles Can Predict Panitumumab Monotherapy Responsiveness in Human Tumor Xenograft Models by Boedigheimer, Michael J, Freeman, Daniel J, Kiaei, Panteha, Damore, Michael A, Radinsky, Robert

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The influence of nonautonomous P elements on hybrid dysgenesis in Drosophila melanogaster by Simmons, M.J, Raymond, J.D, Boedigheimer, M.J, Zunt, J.R

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Use of a mixed tissue RNA design for performance assessments on multiple microarray formats by Thompson, Karol L., Rosenzweig, Barry A., Pine, P. Scott, Retief, Jacques, Turpaz, Yaron, Afshari, Cynthia A., Hamadeh, Hisham K., Damore, Michael A., Boedigheimer, Michael, Blomme, Eric, Ciurlionis, Rita, Waring, Jeffrey F., Fuscoe, James C., Paules, Richard, Tucker, Charles J., Fare, Thomas, Coffey, Ernest M., He, Yudong, Collins, Patrick J., Jarnagin, Kurt, Fujimoto, Susan, Ganter, Brigitte, Kiser, Gretchen, Kaysser-Kranich, Tamma, Sina, Joseph, Sistare, Frank D.

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Expanded functions in the apical cell domain to regulate the growth rate of imaginal discs by Boedigheimer, M.J. (University of California, Irvine.), Nguyen, K.P, Bryant, P.J

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