Type 2 diabetes–associated variants of the MT2 melatonin receptor affect distinct modes of signaling by Karamitri Angeliki, Plouffe Bianca, Bonnefond Amélie, Chen, Min, Gallion, Jonathan, Guillaume Jean-Luc, Hegron Alan, Boissel Mathilde, Canouil Mickaël, Langenberg, Claudia, Wareham, Nicholas J, Le Gouill Christian, Lukasheva Viktoria, Lichtarge Olivier, Froguel Philippe, Bouvier, Michel, Jockers Ralf

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A framework for conducting GWAS using repeated measures data with an application to childhood BMI by Burrows, Kimberley, Heiskala, Anni, Bradfield, Jonathan P., Balkhiyarova, Zhanna, Ning, Lijiao, Boissel, Mathilde, Chan, Yee-Ming, Froguel, Philippe, Bonnefond, Amelie, Hakonarson, Hakon, Alves, Alexessander Couto, Lawlor, Deborah A., Kaakinen, Marika, Järvelin, Marjo-Riitta, Grant, Struan F. A., Tilling, Kate, Prokopenko, Inga, Sebert, Sylvain, Canouil, Mickaël, Warrington, Nicole M.

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Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics by Dance, Arnaud, Fernandes, Justine, Toussaint, Bénédicte, Vaillant, Emmanuel, Boutry, Raphaël, Baron, Morgane, Loiselle, Hélène, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Ibberson, Mark, Marre, Michel, Gernay, Marie, Fadeur, Marjorie, Paquot, Nicolas, Vaxillaire, Martine, Boissel, Mathilde, Amanzougarene, Souhila, Derhourhi, Mehdi, Khamis, Amna, Froguel, Philippe, Bonnefond, Amélie

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Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas by Meulebrouck, Sarah, Scherrer, Victoria, Boutry, Raphaël, Toussaint, Bénédicte, Vaillant, Emmanuel, Dechaume, Aurélie, Loiselle, Hélène, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Marre, Michel, Baron, Morgane, Vaxillaire, Martine, Derhourhi, Mehdi, Boissel, Mathilde, Froguel, Philippe, Bonnefond, Amélie

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Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas by Meulebrouck, Sarah, Scherrer, Victoria, Boutry, Raphaël, Toussaint, Bénédicte, Vaillant, Emmanuel, Dechaume, Aurélie, Loiselle, Hélène, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Marre, Michel, Baron, Morgane, Vaxillaire, Martine, Derhourhi, Mehdi, Boissel, Mathilde, Froguel, Philippe, Bonnefond, Amélie

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Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function by Meulebrouck, Sarah, Merrheim, Judith, Queniat, Gurvan, Bourouh, Cyril, Derhourhi, Mehdi, Boissel, Mathilde, Yi, Xiaoyan, Badreddine, Alaa, Boutry, Raphaël, Leloire, Audrey, Toussaint, Bénédicte, Amanzougarene, Souhila, Vaillant, Emmanuel, Durand, Emmanuelle, Loiselle, Hélène, Huyvaert, Marlène, Dechaume, Aurélie, Scherrer, Victoria, Marchetti, Piero, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Marre, Michel, Roussel, Ronan, Scharfmann, Raphaël, Cnop, Miriam, Canouil, Mickaël, Baron, Morgane, Froguel, Philippe, Bonnefond, Amélie

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Monogenic diabetes characteristics in a transnational multicenter study from Mediterranean countries by Vaxillaire, Martine, Bonnefond, Amélie, Liatis, Stavros, Ben Salem Hachmi, Leila, Jotic, Aleksandra, Boissel, Mathilde, Gaget, Stefan, Durand, Emmanuelle, Vaillant, Emmanuel, Derhourhi, Mehdi, Canouil, Mickaël, Larcher, Nicolas, Allegaert, Frédéric, Medlej, Rita, Chadli, Asma, Belhadj, Azzedine, Chaieb, Molka, Raposo, Joao-Felipe, Ilkova, Hasan, Loizou, Doros, Lalic, Nebojsa, Vassallo, Josanne, Marre, Michel, Froguel, Philippe

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General regression model: A “model‐free” association test for quantitative traits allowing to test for the underlying genetic model by Gloaguen, Emilie, Dizier, Marie‐hélène, Boissel, Mathilde, Rocheleau, Ghislain, Canouil, Mickaël, Froguel, Philippe, Tichet, Jean, Roussel, Ronan, Julier, Cécile, Balkau, Beverley, Mathieu, Flavie

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General regression model: A “model‐free” association test for quantitative traits allowing to test for the underlying genetic model by Gloaguen, Emilie, Dizier, Marie‐hélène, Boissel, Mathilde, Rocheleau, Ghislain, Canouil, Mickaël, Froguel, Philippe, Tichet, Jean, Roussel, Ronan, Julier, Cécile, Balkau, Beverley, Mathieu, Flavie

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Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics by Dance, Arnaud, Fernandes, Justine, Toussaint, Bénédicte, Vaillant, Emmanuel, Boutry, Raphaël, Baron, Morgane, Loiselle, Hélène, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Ibberson, Mark, Marre, Michel, Gernay, Marie, Fadeur, Marjorie, Paquot, Nicolas, Vaxillaire, Martine, Boissel, Mathilde, Amanzougarene, Souhila, Derhourhi, Mehdi, Khamis, Amna, Froguel, Philippe, Bonnefond, Amélie

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Monogenic diabetes characteristics in a transnational multicenter study from Mediterranean countries by Vaxillaire, Martine, Bonnefond, Amélie, Liatis, Stavros, Ben Salem Hachmi, Leila, Jotic, Aleksandra, Boissel, Mathilde, Gaget, Stefan, Durand, Emmanuelle, Vaillant, Emmanuel, Derhourhi, Mehdi, Canouil, Mickaël, Larcher, Nicolas, Allegaert, Frédéric, Medlej, Rita, Chadli, Asma, Belhadj, Azzedine, Chaieb, Molka, Raposo, Joao-Felipe, Ilkova, Hasan, Loizou, Doros, Lalic, Nebojsa, Vassallo, Josanne, Marre, Michel, Froguel, Philippe

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Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci by de Las Fuentes, Lisa, Sung, Yun Ju, Noordam, Raymond, Winkler, Thomas, Feitosa, Mary, Schwander, Karen, Bentley, Amy, Brown, Michael, Guo, Xiuqing, Manning, Alisa, Chasman, Daniel, Aschard, Hugues, Bartz, Traci, Bielak, Lawrence, Campbell, Archie, Cheng, Ching-Yu, Dorajoo, Rajkumar, Hartwig, Fernando, Horimoto, A., Li, Changwei, Li-Gao, Ruifang, Liu, Yongmei, Marten, Jonathan, Musani, Solomon, Ntalla, Ioanna, Rankinen, Tuomo, Richard, Melissa, Sim, Xueling, Smith, Albert, Tajuddin, Salman, Tayo, Bamidele, Vojinovic, Dina, Warren, Helen, Xuan, Deng, Alver, Maris, Boissel, Mathilde, Chai, Jin-Fang, Chen, Xu, Christensen, Kaare, Divers, Jasmin, Evangelou, Evangelos, Gao, Chuan, Girotto, Giorgia, Harris, Sarah, He, Meian, Hsu, Fang-Chi, Kühnel, Brigitte, Laguzzi, Federica, Li, Xiaoyin, Lyytikäinen, Leo-Pekka, Nolte, Ilja, Poveda, Alaitz, Rauramaa, Rainer, Riaz, Muhammad, Rueedi, Rico, Shu, Xiao-Ou, Snieder, Harold, Sofer, Tamar, Takeuchi, Fumihiko, Verweij, Niek, Ware, Erin, Weiss, Stefan, Yanek, Lisa, Amin, Najaf, Arking, Dan, Arnett, Donna, Bergmann, Sven, Boerwinkle, Eric, Brody, Jennifer, Broeckel, Ulrich, Brumat, Marco, Burke, Gregory, Cabrera, Claudia, Canouil, Mickaël, Chee, Miao Li, Chen, Yii-Der Ida, Cocca, Massimiliano, Connell, John, de Silva, H Janaka, de Vries, Paul, Eiriksdottir, Gudny, Faul, Jessica, Fisher, Virginia, Forrester, Terrence, Fox, Ervin, Friedlander, Yechiel, Gao, He, Gigante, Bruna, Giulianini, Franco, Gu, Chi Charles, Gu, Dongfeng, Harris, Tamara, He, Jiang, Heikkinen, Sami, Heng, Chew-Kiat, Hunt, Steven, Ikram, M Arfan, Irvin, Marguerite, Kähönen, Mika, Kavousi, Maryam

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Type 2 diabetes-associated variants of the MT 2 melatonin receptor affect distinct modes of signaling by Karamitri, Angeliki, Plouffe, Bianca, Bonnefond, Amélie, Chen, Min, Gallion, Jonathan, Guillaume, Jean-Luc, Hegron, Alan, Boissel, Mathilde, Canouil, Mickaël, Langenberg, Claudia, Wareham, Nicholas J, Le Gouill, Christian, Lukasheva, Viktoria, Lichtarge, Olivier, Froguel, Philippe, Bouvier, Michel, Jockers, Ralf

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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity by Kilpeläinen, Tuomas, Bentley, Amy, Noordam, Raymond, Sung, Yun Ju, Schwander, Karen, Winkler, Thomas, Jakupović, Hermina, Chasman, Daniel, Manning, Alisa, Ntalla, Ioanna, Aschard, Hugues, Brown, Michael, de Las Fuentes, Lisa, Franceschini, Nora, Guo, Xiuqing, Vojinovic, Dina, Aslibekyan, Stella, Feitosa, Mary, Kho, Minjung, Musani, Solomon, Richard, Melissa, Wang, Heming, Wang, Zhe, Bartz, Traci, Bielak, Lawrence, Campbell, Archie, Dorajoo, Rajkumar, Fisher, Virginia, Hartwig, Fernando, Horimoto, Andrea, Li, Changwei, Lohman, Kurt, Marten, Jonathan, Sim, Xueling, Smith, Albert, Tajuddin, Salman, Alver, Maris, Amini, Marzyeh, Boissel, Mathilde, Chai, Jin Fang, Chen, Xu, Divers, Jasmin, Evangelou, Evangelos, Gao, Chuan, Graff, Mariaelisa, Harris, Sarah, He, Meian, Hsu, Fang-Chi, Jackson, Anne, Zhao, Jing Hua, Kraja, Aldi, Kühnel, Brigitte, Laguzzi, Federica, Lyytikäinen, Leo-Pekka, Nolte, Ilja, Rauramaa, Rainer, Riaz, Muhammad, Robino, Antonietta, Rueedi, Rico, Stringham, Heather, Takeuchi, Fumihiko, van Der Most, Peter, Varga, Tibor, Verweij, Niek, Ware, Erin, Wen, Wanqing, Li, Xiaoyin, Yanek, Lisa, Amin, Najaf, Arnett, Donna, Boerwinkle, Eric, Brumat, Marco, Cade, Brian, Canouil, Mickaël, Chen, Yii-Der Ida, Concas, Maria Pina, Connell, John, de Mutsert, Renée, de Silva, H Janaka, de Vries, Paul, Demirkan, Ayşe, Ding, Jingzhong, Eaton, Charles, Faul, Jessica, Friedlander, Yechiel, Gabriel, Kelley, Ghanbari, Mohsen, Giulianini, Franco, Gu, Chi Charles, Gu, Dongfeng, Harris, Tamara, He, Jiang, Heikkinen, Sami, Heng, Chew-Kiat, Hunt, Steven, Ikram, M Arfan, Jonas, Jost, Koh, Woon-Puay, Komulainen, Pirjo, Krieger, Jose

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A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure by Sung, Yun Ju, de Las Fuentes, Lisa, Winkler, Thomas, Chasman, Daniel, Bentley, Amy, Kraja, Aldi, Ntalla, Ioanna, Warren, Helen, Guo, Xiuqing, Schwander, Karen, Manning, Alisa, Brown, Michael, Aschard, Hugues, Feitosa, Mary, Franceschini, Nora, Lu, Yingchang, Cheng, Ching-Yu, Sim, Xueling, Vojinovic, Dina, Marten, Jonathan, Musani, Solomon, Kilpeläinen, Tuomas, Richard, Melissa, Aslibekyan, Stella, Bartz, Traci, Dorajoo, Rajkumar, Li, Changwei, Liu, Yongmei, Rankinen, Tuomo, Smith, Albert Vernon, Tajuddin, Salman, Tayo, Bamidele, Zhao, Wei, Zhou, Yanhua, Matoba, Nana, Sofer, Tamar, Alver, Maris, Amini, Marzyeh, Boissel, Mathilde, Chai, Jin Fang, Chen, Xu, Divers, Jasmin, Gandin, Ilaria, Gao, Chuan, Giulianini, Franco, Goel, Anuj, Harris, Sarah, Hartwig, Fernando, He, Meian, Horimoto, Andrea, Hsu, Fang-Chi, Jackson, Anne, Kammerer, Candace, Kasturiratne, Anuradhani, Komulainen, Pirjo, Kühnel, Brigitte, Leander, Karin, Lee, Wen-Jane, Lin, Keng-Hung, Luan, Jian'An, Lyytikäinen, Leo-Pekka, Mckenzie, Colin, Nelson, Christopher, Noordam, Raymond, Scott, Robert, Sheu, Wayne, Stančáková, Alena, Takeuchi, Fumihiko, van Der Most, Peter, Varga, Tibor, Waken, Robert, Wang, Heming, Wang, Yajuan, Ware, Erin, Weiss, Stefan, Wen, Wanqing, Yanek, Lisa, Zhang, Weihua, Zhao, Jing Hua, Afaq, Saima, Alfred, Tamuno, Amin, Najaf, Arking, Dan, Aung, Tin, Barr, R Graham, Bielak, Lawrence, Boerwinkle, Eric, Bottinger, Erwin, Braund, Peter, Brody, Jennifer, Broeckel, Ulrich, Cade, Brian, Campbell, Archie, Canouil, Mickaël, Chakravarti, Aravinda, Cocca, Massimiliano, Collins, Francis, Connell, John, de Mutsert, Renée, de Silva, H Janaka

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Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions by de Vries, Paul, Brown, Michael, Bentley, Amy, Sung, Yun, Winkler, Thomas, Ntalla, Ioanna, Schwander, Karen, Kraja, Aldi, Guo, Xiuqing, Franceschini, Nora, Cheng, Ching-Yu, Sim, Xueling, Vojinovic, Dina, Huffman, Jennifer, Musani, Solomon, Li, Changwei, Feitosa, Mary, Richard, Melissa, Noordam, Raymond, Aschard, Hugues, Bartz, Traci, Bielak, Lawrence, Deng, Xuan, Dorajoo, Rajkumar, Lohman, Kurt, Manning, Alisa, Rankinen, Tuomo, Smith, Albert, Tajuddin, Salman, Evangelou, Evangelos, Graff, Mariaelisa, Alver, Maris, Boissel, Mathilde, Chai, Jin Fang, Chen, Xu, Divers, Jasmin, Gandin, Ilaria, Gao, Chuan, Goel, Anuj, Hagemeijer, Yanick, Harris, Sarah, Hartwig, Fernando, He, Meian, Horimoto, Andrea, Hsu, Fang-Chi, Jackson, Anne, Kasturiratne, Anuradhani, Komulainen, Pirjo, Kühnel, Brigitte, Laguzzi, Federica, Lee, Joseph, Luan, Jian'An, Lyytikäinen, Leo-Pekka, Matoba, Nana, Nolte, Ilja, Pietzner, Maik, Riaz, Muhammad, Said, M Abdullah, Scott, Robert, Sofer, Tamar, Stančáková, Alena, Takeuchi, Fumihiko, Tayo, Bamidele, van Der Most, Peter, Varga, Tibor, Wang, Yajuan, Ware, Erin, Wen, Wanqing, Yanek, Lisa, Zhang, Weihua, Zhao, Jing Hua, Afaq, Saima, Amin, Najaf, Amini, Marzyeh, Arking, Dan, Aung, Tin, Ballantyne, Christie, Boerwinkle, Eric, Broeckel, Ulrich, Campbell, Archie, Canouil, Mickaël, Charumathi, Sabanayagam, Chen, Yii-Der Ida, Connell, John, de Faire, Ulf, de Las Fuentes, Lisa, de Mutsert, Renée, de Silva, H Janaka, Ding, Jingzhong, Dominiczak, Anna, Duan, Qing, Eaton, Charles, Eppinga, Ruben, Faul, Jessica, Fisher, Virginia, Forrester, Terrence, Franco, Oscar, Friedlander, Yechiel, Ghanbari, Mohsen, Giulianini, Franco

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General regression model: A “model‐free” association test for quantitative traits allowing to test for the underlying genetic model by Gloaguen, Emilie, Dizier, Marie‐Hélène, Boissel, Mathilde, Rocheleau, Ghislain, Canouil, Mickaël, Froguel, Philippe, Tichet, Jean, Roussel, Ronan, Julier, Cécile, Balkau, Beverley, Mathieu, Flavie

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Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants by Hegron, Alan, Huh, Eunna, Deupi, Xavier, Sokrat, Badr, Gao, Wenwen, Le Gouill, Christian, Canouil, Mickaël, Boissel, Mathilde, Charpentier, Guillaume, Roussel, Ronan, Balkau, Beverley, Froguel, Philippe, Plouffe, Bianca, Bonnefond, Amélie, Lichtarge, Olivier, Jockers, Ralf, Bouvier, Michel

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Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants by Hegron, Alan, Huh, Eunna, Deupi, Xavier, Sokrat, Badr, Gao, Wenwen, Le Gouill, Christian, Canouil, Mickaël, Boissel, Mathilde, Charpentier, Guillaume, Roussel, Ronan, Balkau, Beverley, Froguel, Philippe, Plouffe, Bianca, Bonnefond, Amélie, Lichtarge, Olivier, Jockers, Ralf, Bouvier, Michel

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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries by Feitosa, Mary, Kraja, Aldi, Chasman, Daniel, Sung, Yun, Winkler, Thomas, Ntalla, Ioanna, Guo, Xiuqing, Franceschini, Nora, Cheng, Ching-Yu, Sim, Xueling, Vojinovic, Dina, Marten, Jonathan, Musani, Solomon, Li, Changwei, Bentley, Amy, Brown, Michael, Schwander, Karen, Richard, Melissa, Noordam, Raymond, Aschard, Hugues, Bartz, Traci, Bielak, Lawrence, Dorajoo, Rajkumar, Fisher, Virginia, Hartwig, Fernando, Horimoto, Andrea, Lohman, Kurt, Manning, Alisa, Rankinen, Tuomo, Smith, Albert, Tajuddin, Salman, Wojczynski, Mary, Alver, Maris, Boissel, Mathilde, Cai, Qiuyin, Campbell, Archie, Chai, Jin Fang, Chen, Xu, Divers, Jasmin, Gao, Chuan, Goel, Anuj, Hagemeijer, Yanick, Harris, Sarah, He, Meian, Hsu, Fang-Chi, Jackson, Anne, Kähönen, Mika, Kasturiratne, Anuradhani, Komulainen, Pirjo, Kühnel, Brigitte, Laguzzi, Federica, Luan, Jian'An, Matoba, Nana, Nolte, Ilja, Padmanabhan, Sandosh, Riaz, Muhammad, Rueedi, Rico, Robino, Antonietta, Said, M Abdullah, Scott, Robert, Sofer, Tamar, Stančáková, Alena, Takeuchi, Fumihiko, Tayo, Bamidele, van Der Most, Peter, Varga, Tibor, Vitart, Veronique, Wang, Yajuan, Ware, Erin, Warren, Helen, Weiss, Stefan, Wen, Wanqing, Yanek, Lisa, Zhang, Weihua, Zhao, Jing Hua, Afaq, Saima, Amin, Najaf, Amini, Marzyeh, Arking, Dan, Aung, Tin, Boerwinkle, Eric, Borecki, Ingrid, Broeckel, Ulrich, Brown, Morris, Brumat, Marco, Burke, Gregory, Canouil, Mickaël, Chakravarti, Aravinda, Charumathi, Sabanayagam, Ida Chen, Yii-Der, Connell, John, Correa, Adolfo, de Las Fuentes, Lisa, de Mutsert, Renée, de Silva, H Janaka, Deng, Xuan, Ding, Jingzhong, Duan, Qing, Eaton, Charles, Ehret, Georg

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