Alzheimer's disease: presenilin 2-sparing γ-secretase inhibition is a tolerable Aβ peptide-lowering strategy by Borgegård, Tomas, Gustavsson, Susanne, Nilsson, Charlotte, Parpal, Santiago, Klintenberg, Rebecka, Berg, Anna-Lena, Rosqvist, Susanne, Serneels, Lutgarde, Svensson, Samuel, Olsson, Fredrik, Jin, Shaobo, Yan, Hongmei, Wanngren, Johanna, Jureus, Anders, Ridderstad-Wollberg, Anna, Wollberg, Patrik, Stockling, Kenneth, Karlström, Helena, Malmberg, Asa, Lund, Johan, Arvidsson, Per I, De Strooper, Bart, Lendahl, Urban, Lundkvist, Johan

Get full text

Second Generation γ-Secretase Modulators Exhibit Different Modulation of Notch β and Aβ Production by Wanngren, Johanna, Ottervald, Jan, Parpal, Santiago, Portelius, Erik, Strömberg, Kia, Borgegård, Tomas, Klintenberg, Rebecka, Juréus, Anders, Blomqvist, Jenny, Blennow, Kaj, Zetterberg, Henrik, Lundkvist, Johan, Rosqvist, Susanne, Karlström, Helena

Get full text

First and Second Generation γ-Secretase Modulators (GSMs) Modulate Amyloid-β (Aβ) Peptide Production through Different Mechanisms by Borgegard, Tomas, Juréus, Anders, Olsson, Fredrik, Rosqvist, Susanne, Sabirsh, Alan, Rotticci, Didier, Paulsen, Kim, Klintenberg, Rebecka, Yan, Hongmei, Waldman, Magnus, Stromberg, Kia, Nord, Johan, Johansson, Jonas, Regner, Anna, Parpal, Santiago, Malinowsky, David, Radesater, Ann-Cathrin, Li, Tingsheng, Singh, Rajeshwar, Eriksson, Hakan, Lundkvist, Johan

Get full text