Maximizing Diversity from a Kinase Screen: Identification of Novel and Selective pan-Trk Inhibitors for Chronic Pain by Stachel, Shawn J, Sanders, John M, Henze, Darrell A, Rudd, Mike T, Su, Hua-Poo, Li, Yiwei, Nanda, Kausik K, Egbertson, Melissa S, Manley, Peter J, Jones, Kristen L. G, Brnardic, Edward J, Green, Ahren, Grobler, Jay A, Hanney, Barbara, Leitl, Michael, Lai, Ming-Tain, Munshi, Vandna, Murphy, Dennis, Rickert, Keith, Riley, Daniel, Krasowska-Zoladek, Alicja, Daley, Christopher, Zuck, Paul, Kane, Stephanie A, Bilodeau, Mark T

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Recent advances in TRPV4 agonists and antagonists by Lawhorn, Brian G., Brnardic, Edward J., Behm, David J.

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3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts by Brnardic, Edward J., Fraley, Mark E., Garbaccio, Robert M., Layton, Mark E., Sanders, John M., Culberson, Chris, Jacobson, Marlene A., Magliaro, Brian C., Hutson, Pete H., O’Brien, Julie A., Huszar, Sarah L., Uslaner, Jason M., Fillgrove, Kerry L., Tang, Cuyue, Kuo, Yuhsin, Sur, Sylvie M., Hartman, George D.

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Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid‑4 (TRPV4) by Brnardic, Edward J, Ye, Guosen, Brooks, Carl, Donatelli, Carla, Barton, Linda, McAtee, Jeff, Sanchez, Robert M, Shu, Arthur, Erhard, Karl, Terrell, Lamont, Graczyk-Millbrandt, Grazyna, He, Yanan, Costell, Melissa H, Behm, David J, Roethke, Theresa, Stoy, Patrick, Holt, Dennis A, Lawhorn, Brian G

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Discovery of GSK3527497: A Candidate for the Inhibition of Transient Receptor Potential Vanilloid‑4 (TRPV4) by Brooks, Carl A, Barton, Linda S, Behm, David J, Brnardic, Edward J, Costell, Melissa H, Holt, Dennis A, Jolivette, Larry J, Matthews, Jay M, McAtee, John J, McCleland, Brent W, Patterson, Jaclyn R, Pero, Joseph E, Rivero, Ralph A, Roethke, Theresa J, Sanchez, Robert M, Shenje, Raynold, Terrell, Lamont R, Lawhorn, Brian G

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Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid‑4 with in Vivo Activity in a Pulmonary Edema Model by Pero, Joseph E, Matthews, Jay M, Behm, David J, Brnardic, Edward J, Brooks, Carl, Budzik, Brian W, Costell, Melissa H, Donatelli, Carla A, Eisennagel, Stephen H, Erhard, Karl, Fischer, Michael C, Holt, Dennis A, Jolivette, Larry J, Li, Huijie, Li, Peng, McAtee, John J, McCleland, Brent W, Pendrak, Israil, Posobiec, Lorraine M, Rivera, Katrina L.K, Rivero, Ralph A, Roethke, Theresa J, Sender, Matthew R, Shu, Arthur, Terrell, Lamont R, Vaidya, Kalindi, Xu, Xiaoping, Lawhorn, Brian G

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Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors by Brnardic, Edward J., Garbaccio, Robert M., Fraley, Mark E., Tasber, Edward S., Steen, Justin T., Arrington, Kenneth L., Dudkin, Vadim Y., Hartman, George D., Stirdivant, Steven M., Drakas, Bob A., Rickert, Keith, Walsh, Eileen S., Hamilton, Kelly, Buser, Carolyn A., Hardwick, James, Tao, Weikang, Beck, Stephen C., Mao, Xianzhi, Lobell, Robert B., Sepp-Lorenzino, Laura, Yan, Youwei, Ikuta, Mari, Munshi, Sanjeev K., Kuo, Lawrence C., Kreatsoulas, Constantine

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3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6 by Fraley, Mark E., Steen, Justin T., Brnardic, Edward J., Arrington, Kenneth L., Spencer, Keith L., Hanney, Barbara A., Kim, Yuntae, Hartman, George D., Stirdivant, Steven M., Drakas, Bob A., Rickert, Keith, Walsh, Eileen S., Hamilton, Kelly, Buser, Carolyn A., Hardwick, James, Tao, Weikang, Beck, Stephen C., Mao, Xianzhi, Lobell, Robert B., Sepp-Lorenzino, Laura, Yan, Youwei, Ikuta, Mari, Munshi, Sanjeev K., Kuo, Lawrence C., Kreatsoulas, Constantine

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Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor by Garbaccio, Robert M, Brnardic, Edward J, Fraley, Mark E, Hartman, George D, Hutson, Pete H, O'Brien, Julie A, Magliaro, Brian C, Uslaner, Jason M, Huszar, Sarah L, Fillgrove, Kerry L, Small, James H, Tang, Cuyue, Kuo, Yuhsin, Jacobson, Marlene A

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Optimization of a pyrazoloquinolinone class of Chkl kinase inhibitors by BRNARDIC, Edward J, GARBACCIO, Robert M, RICKERT, Keith, WALSH, Eileen S, HAMILTON, Kelly, BUSER, Carolyn A, HARDWICK, James, WEIKANG TAO, BECK, Stephen C, XIANZHI MAO, LOBELL, Robert B, SEPP-LORENZINO, Laura, FRALEY, Mark E, YOUWEI YAN, IKUTA, Mari, MUNSHI, Sanjeev K, KUO, Lawrence C, KREATSOULAS, Constantine, TASBER, Edward S, STEEN, Justin T, ARRINGTON, Kenneth L, DUDKIN, Vadim Y, HARTMAN, George D, STIRDIVANT, Steven M, DRAKAS, Bob A

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Identification and in Vivo Evaluation of Liver X Receptor β‑Selective Agonists for the Potential Treatment of Alzheimer’s Disease by Stachel, Shawn J, Zerbinatti, Celina, Rudd, Michael T, Cosden, Mali, Suon, Sokreine, Nanda, Kausik K, Wessner, Keith, DiMuzio, Jillian, Maxwell, Jill, Wu, Zhenhua, Uslaner, Jason M, Michener, Maria S, Szczerba, Peter, Brnardic, Edward, Rada, Vanessa, Kim, Yuntae, Meissner, Robert, Wuelfing, Peter, Yuan, Yang, Ballard, Jeanine, Holahan, Marie, Klein, Daniel J, Lu, Jun, Fradera, Xavier, Parthasarathy, Gopal, Uebele, Victor N, Chen, Zhongguo, Li, Yingjie, Li, Jian, Cooke, Andrew J, Bennett, D. Jonathan, Bilodeau, Mark T, Renger, John

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