PKDB: Polycystic Kidney Disease Mutation Database-a gene variant database for autosomal dominant polycystic kidney disease by Gout, Alexander M., Martin, Neilson C., Brown, Alastair F., Ravine, David

Get full text

MuStaR™ and other software for locus-specific mutation databases by Brown, Alastair F., McKie, Mark A.

Get full text

Quality and efficacy of Multidisciplinary Team (MDT) quality assessment tools and discussion checklists: a systematic review by Brown, George T F, Bekker, Hilary L, Young, Alastair L

Get full text

EukRef: Phylogenetic curation of ribosomal RNA to enhance understanding of eukaryotic diversity and distribution by Del Campo, Javier, Kolisko, Martin, Boscaro, Vittorio, Santoferrara, Luciana F, Nenarokov, Serafim, Massana, Ramon, Guillou, Laure, Simpson, Alastair, Berney, Cedric, de Vargas, Colomban, Brown, Matthew W, Keeling, Patrick J, Wegener Parfrey, Laura

Get full text

Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome by Barr, Alastair J., Ugochukwu, Emilie, Lee, Wen Hwa, King, Oliver N.F., Filippakopoulos, Panagis, Alfano, Ivan, Savitsky, Pavel, Burgess-Brown, Nicola A., Müller, Susanne, Knapp, Stefan

Get full text

Relationship between Patient Health Questionnaire (PHQ-9) and Montgomery-Asberg Depression Rating Scale (MADRS) total scores in older adults with major depressive disorder: An anal... by Kim, Helena K., Lenze, Eric J., Ainsworth, Nicholas J., Blumberger, Daniel M., Brown, Patrick J., Flint, Alastair J., Karp, Jordan F., Lavretsky, Helen, Lenard, Emily, Miller, J. Philip, Reynolds, Charles F., Roose, Steven P., Mulsant, Benoit H.

Get full text

From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease by Brown, Alastair J H, Bradley, Sophie J, Marshall, Fiona H, Brown, Giles A, Bennett, Kirstie A, Brown, Jason, Cansfield, Julie E, Cross, David M, de Graaf, Chris, Hudson, Brian D, Dwomoh, Louis, Dias, João M, Errey, James C, Hurrell, Edward, Liptrot, Jan, Mattedi, Giulio, Molloy, Colin, Nathan, Pradeep J, Okrasa, Krzysztof, Osborne, Greg, Patel, Jayesh C, Pickworth, Mark, Robertson, Nathan, Shahabi, Shahram, Bundgaard, Christoffer, Phillips, Keith, Broad, Lisa M, Goonawardena, Anushka V, Morairty, Stephen R, Browning, Michael, Perini, Francesca, Dawson, Gerard R, Deakin, John F W, Smith, Robert T, Sexton, Patrick M, Warneck, Julie, Vinson, Mary, Tasker, Tim, Tehan, Benjamin G, Teobald, Barry, Christopoulos, Arthur, Langmead, Christopher J, Jazayeri, Ali, Cooke, Robert M, Rucktooa, Prakash, Congreve, Miles S, Weir, Malcolm, Tobin, Andrew B

Get full text

Hyperoxia during venoarterial ECMO: Culprit or co-variate? A comment from the BLENDER investigators by Premraj, Lavienraj, Brown, Alastair, Burrell, Aidan, Fraser, John F, Pilcher, David

Get full text

Lung adenocarcinoma promotion by air pollutants by Hill, William, Lim, Emilia L., Weeden, Clare E., Lee, Claudia, Augustine, Marcellus, Chen, Kezhong, Kuan, Feng-Che, Marongiu, Fabio, Evans, Edward J., Moore, David A., Rodrigues, Felipe S., Pich, Oriol, Bakker, Bjorn, Cha, Hongui, Myers, Renelle, van Maldegem, Febe, Boumelha, Jesse, Veeriah, Selvaraju, Rowan, Andrew, Naceur-Lombardelli, Cristina, Karasaki, Takahiro, Sivakumar, Monica, De, Swapnanil, Caswell, Deborah R., Nagano, Ai, Black, James R. M., Martínez-Ruiz, Carlos, Ryu, Min Hyung, Huff, Ryan D., Li, Shijia, Favé, Marie-Julie, Magness, Alastair, Suárez-Bonnet, Alejandro, Priestnall, Simon L., Lüchtenborg, Margreet, Lavelle, Katrina, Pethick, Joanna, Hardy, Steven, McRonald, Fiona E., Lin, Meng-Hung, Troccoli, Clara I., Ghosh, Moumita, Miller, York E., Merrick, Daniel T., Keith, Robert L., Al Bakir, Maise, Bailey, Chris, Hill, Mark S., Saal, Lao H., Chen, Yilun, George, Anthony M., Abbosh, Christopher, Kanu, Nnennaya, Lee, Se-Hoon, McGranahan, Nicholas, Berg, Christine D., Sasieni, Peter, Houlston, Richard, Turnbull, Clare, Lam, Stephen, Awadalla, Philip, Grönroos, Eva, Downward, Julian, Jacks, Tyler, Carlsten, Christopher, Malanchi, Ilaria, Hackshaw, Allan, Litchfield, Kevin, DeGregori, James, Jamal-Hanjani, Mariam, Swanton, Charles

Get full text

Poor Sleep is Common in Treatment-Resistant Late-life Depression and Associated With Poorer Antidepressant Response: Findings From the OPTIMUM Clinical Trial by Mak, Michael S.B., Gebara, Marie Anne, Lenze, Eric J., Blumberger, Daniel M., Brown, Patrick J., Cristancho, Pilar, Flint, Alastair J., Karp, Jordan F., Lavretsky, Helen, Miller, J. Philip, Reynolds, Charles F., Roose, Steven P., Mulsant, Benoit H., Stahl, Sarah T.

Get full text

Change in patient‐centered outcomes of psychological well‐being, sleep, and suicidality following treatment with intravenous ketamine for late‐life treatment‐resistant depression... by Vanderschelden, Benjamin, Gebara, Marie Anne, Oughli, Hanadi Ajam, Butters, Meryl A., Brown, Patrick J., Farber, Nuri B., Flint, Alastair J., Karp, Jordan F., Lavretsky, Helen, Mulsant, Benoit H., Reynolds, Charles F., Roose, Steven P., Lenze, Eric J.

Get full text

Exercise versus usual care after non-reconstructive breast cancer surgery (UK PROSPER): multicentre randomised controlled trial and economic evaluation by Bruce, Julie, Mazuquin, Bruno, Canaway, Alastair, Hossain, Anower, Williamson, Esther, Mistry, Pankaj, Lall, Ranjit, Petrou, Stavros, Lamb, Sarah E, Rees, Sophie, Padfield, Emma, Vidya, Raghavan, Thompson, Alastair M, Lait, C, Hegarty, C, van Laar, M, Harkin, C, Chowdhury, L, Richmond, H, Betteley, L, Srikesavan, C, Newman, M, Moser, J, Tomlins, A, McEvoy, K, Roy, P G, Soulsby, R, Hoar, F, McNicholas, JS, Azmy, I, Mitchell, S, Osborne, C, Donnelly, J, Babu, E, van de Ploeg, N, Sircar, T, Makam, K, McLoughlin, E, Noblet, M, Soumian, S, Thorne, A, Wagstaff, L, Fort, L, Rushton, C, Evans, M, Simpson, A, Ridgeway, L, Pilgrim, D, Graves, L, Jones, K, Holt, J, Ekers, N, McMullen, A, Lindsay, C, Wright, S, Bower, R, Horne, S, Rook, S, Redfern, N, Allen, A, Greenwood, S, Stephenson, A, Conway, R, Edley, C, Pitts, J, Layte, N, Thomas, H, Johnson, C, Heath, A, Beadle, L, Scarisbrick, R, DeBeer, D, Dungey, D, Stokes, Y, Calloway, S, Brown, H, Clarke, N, Daffern, C, Willis, A, Adjei, H, Muthiah, C

Get full text

Intravenous Ketamine for Late-Life Treatment-Resistant Depression: A Pilot Study of Tolerability, Safety, Clinical Benefits, and Effect on Cognition by Oughli, Hanadi Ajam, Gebara, Marie Anne, Ciarleglio, Adam, Lavretsky, Helen, Brown, Patrick J., Flint, Alastair J., Farber, Nuri B., Karp, Jordan F., Mulsant, Benoit H., Reynolds, Charles F., Roose, Steven P., Yang, Lei, Butters, Meryl A., Lenze, Eric J.

Get full text

Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint pha... by Thompson, Richard E, Lane, Karen, Mayo, Steven W, Bistran-Hall, Amanda J, Ullman, Natalie, Dawson, Jesse, Betz, Joshua F, Sugar, Elizabeth A, Hao, Yi, Caron, Jean-Louis, Harrigan, Mark R, Bulters, Diederik, Chicoine, Michael R, Patel, Hiren, Dodd, Robert, Wolfe, Stacey, Money, P Lynn, Mitchell, Patrick, Sarabia, Rosario, Zuccarello, Mario, Abdul-Rahim, Azmil, Ahmed, Azam, Altschul, David, Amin-Hanjani, Sepideh, Barrer, Steven J., Becker, Kyra J., Bergman, Thomas, Braun, Jamie, Brindley, Peter, Broaddus, William C., Cao, Ying, Chalela, Julio, Chang, Tiffany, Chorro, Indalecio Moran, Csiba, Laszlo, Diringer, Michael, Dlugash, Rachel, Economas, Tracey, Enriquez, Pedro, Ezer, Erzsebet, Feng, Hua, Franz, Douglas, Galicich, Walter, Gonzalez, Alejandro Carrasco, Grabarits, Christina, Greenberg, Steven, Gress, Daryl, Hall, Christiana, Hoesch, Robert, Hoh, Brian L., Houser, Jennifer, Hu, Rong, Hussain, Mohammed Akbar, James, Robert F., Jeon, Esther, Karlen, Nicki, Keric, Naureen, Kerz, Thomas, Knopman, Jared, Krishnamurthy, Satish, Kumar, Avinash, MacDonald, Joel, Major, Otto, Malhorta, Rishi, McCaul, Scott, Mohan, Krishna K., Muir, Keith, Muñoz, Lorenzo, Nakaji, Peter, Nee, Alex, Nekoovaght-Tak, Saman, O'Kane, Roddy, Okasha, Mohamed, O'Kelly, Cian, Ostapkovich, Noeleen, Pandey, Aditya, Quinn, Terry, Rajajee, Ventatakrishna, Rehman, Mohammed, Reimer, Ronald, Rybinnik, Igor, Sansing, Lauren, Schneck, Michael, Schuerer, Ludwig, Seder, David B., Sheth, Kevin, Tamayo, Gonzalo, Tanczos, Krisztian, Taussky, Philipp, Thomas, Kathrine, Tran, Huy, Tucker, Kristi, Ungar, Lior, Varelas, Panos, Wang, Ying, Whitworth, Louis Tony, Willis, Byron, Wright, Shawn E., Yi, Xuxia, Zomorodi, Ali

Get full text

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA by Abbosh, Christopher, Frankell, Alexander M., Harrison, Thomas, Kisistok, Judit, Garnett, Aaron, Johnson, Laura, Veeriah, Selvaraju, Moreau, Mike, Chesh, Adrian, Chaunzwa, Tafadzwa L., Weiss, Jakob, Schroeder, Morgan R., Ward, Sophia, Grigoriadis, Kristiana, Shahpurwalla, Aamir, Litchfield, Kevin, Puttick, Clare, Biswas, Dhruva, Karasaki, Takahiro, Black, James R. M., Martínez-Ruiz, Carlos, Bakir, Maise Al, Pich, Oriol, Watkins, Thomas B. K., Lim, Emilia L., Huebner, Ariana, Moore, David A., Godin-Heymann, Nadia, L’Hernault, Anne, Bye, Hannah, Odell, Aaron, Roberts, Paula, Gomes, Fabio, Patel, Akshay J., Manzano, Elizabeth, Hiley, Crispin T., Carey, Nicolas, Riley, Joan, Cook, Daniel E., Hodgson, Darren, Stetson, Daniel, Barrett, J. Carl, Kortlever, Roderik M., Evan, Gerard I., Hackshaw, Allan, Daber, Robert D., Shaw, Jacqui A., Aerts, Hugo J. W. L., Licon, Abel, Stahl, Josh, Jamal-Hanjani, Mariam, Birkbak, Nicolai J., McGranahan, Nicholas, Swanton, Charles

Get full text

Loss of the insulin receptor in murine megakaryocytes/platelets causes thrombocytosis and alterations in IGF signalling by Moore, Samantha F, Williams, Christopher M, Brown, Edward, Blair, Thomas A, Harper, Matthew T, Coward, Richard J, Poole, Alastair W, Hers, Ingeborg

Get full text

Phase 1/2a trial of intravenous BAL101553, a novel controller of the spindle assembly checkpoint, in advanced solid tumours by Kristeleit, Rebecca, Evans, Jeffry, Molife, L. Rhoda, Tunariu, Nina, Shaw, Heather, Slater, Sarah, Haris, Noor R. Md, Brown, Nicholas F., Forster, Martin D., Diamantis, Nikolaos, Rulach, Robert, Greystoke, Alastair, Asghar, Uzma, Rata, Mihaela, Anderson, Stephanie, Bachmann, Felix, Hannah, Alison, Kaindl, Thomas, Lane, Heidi A., Larger, Patrice J., Schmitt-Hoffmann, Anne, Engelhardt, Marc, Tzankov, Alexandar, Plummer, Ruth, Lopez, Juanita

Get full text

Debridement, Curettage, and Bone Marrow Stimulation: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle by Hannon, Charles P., Bayer, Steve, Murawski, Christopher D., Canata, Gian Luigi, Clanton, Thomas O., Haverkamp, Daniel, Lee, Jin Woo, O’Malley, Martin J., Yinghui, Hua, Stone, James W., Ackermann, Jakob, Adams, Samuel B., Andrews, Carol L., Angthong, Chayanin, Batista, Jorge P., Baur, Onno L., Becher, Christoph, Berlet, Gregory C., Boakye, Lorraine A. T., Brown, Alexandra J., Buda, Roberto, Calder, James D.F., Carreira, Dominic S., Dahmen, Jari, D’Hooghe, Pieter, DiGiovanni, Christopher W., Dombrowski, Malcolm E., Drakos, Mark C., Ferkel, Richard D., Ferrao, Paulo N. F., Fortier, Lisa A., Glazebrook, Mark, Giza, Eric, Gomaa, Mohamed, Görtz, Simon, Haleem, Amgad M., Hamid, Kamran S., Hangody, Laszlo, Hertel, Jay, Hintermann, Beat, Hogan, MaCalus V., Hunt, Kenneth J., Hurley, Eoghan T., Karlsson, Jón, Kearns, Stephen R., Kennedy, John G., Kerkhoffs, Gino M. M. J., Kim, Hak Jun, Kong, Siu Wah, Labib, Sameh A., Lambers, Kaj T. A., Bae Lee, Keun, Ling, Jeffrey S., Longo, Umile Giuseppe, Marangon, Alberto, McCollum, Graham, Mitchell, Adam W., Mittwede, Peter N., Nehrer, Stefan, Niemeyer, Philipp, Nunley, James A., Osei-Hwedieh, David O., Paul, Jochen, Pearce, Christopher J., Pereira, Helder, Popchak, Adam, Prado, Marcelo P., Raikin, Steven M., Reilingh, Mikel L., Rothrauff, Benjamin B., Schon, Lew C., Shimozono, Yoshiharu, Simpson, Helene, Smyth, Niall A., Sofka, Carolyn M., Spennacchio, Pietro, Sullivan, Martin, Takao, Masato, Tanaka, Yasuhito, Thordarson, David B., Tuan, Rocky, Valderrabano, Victor, van Bergen, Christiaan J.A., van Dijk, C. Niek, van Dijk, Pim A.D., Vannini, Francesca, Vaseenon, Tanawat, Walther, Markus, Wiewiorski, Martin, Xu, Xiangyang, Yasui, Youichi, Yoshimura, Ichiro, Younger, Alastair S. E., Zhang, Zijun

Get full text

First-in-man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M 1 -receptor partial agonist for the treatment of dementias by Bakker, Charlotte, Tasker, Tim, Liptrot, Jan, Hart, Ellen P, Klaassen, Erica S, Prins, Samantha, van der Doef, Thalia F, Brown, Giles A, Brown, Alastair, Congreve, Miles, Weir, Malcolm, Marshall, Fiona H, Cross, David M, Groeneveld, Geert Jan, Nathan, Pradeep J

Get full text

Statistical analysis plan for a cluster randomised controlled trial to compare screening, feedback and intervention for child anxiety problems to usual school practice: identifying... by Ball, Susan, Reardon, Tessa, Creswell, Cathy, Taylor, Lucy, Brown, Paul, Ford, Tamsin, Gray, Alastair, Hill, Claire, Jasper, Bec, Larkin, Michael, Macdonald, Ian, Morgan, Fran, Pollard, Jack, Sancho, Michelle, Sniehotta, Falko F, Spence, Susan H, Stainer, Jason, Stallard, Paul, Violato, Mara, Ukoumunne, Obioha C

Get full text