Making clinical decisions based on measurable residual disease improves the outcome in multiple myeloma by Martinez-Lopez, Joaquin, Alonso, Rafael, Wong, Sandy W., Rios, Rafael, Shah, Nina, Ruiz-Heredia, Yanira, Sanchez-Pina, Jose Maria, Sanchez, Ricardo, Bahri, Natasha, Zamanillo, Irene, Poza, Maria, Buenache, Natalia, Encinas, Cristina, Juarez, Luis, Miras, Fatima, Collado, Luis, Barrio, Santiago, Martin, Thomas, Cedena, Maria Teresa, Wolf, Jeffrey

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Clonal competition assays identify fitness signatures in cancer progression and resistance in multiple myeloma by Haertle, Larissa, Munawar, Umair, Hernández, Hipólito N. C., Arroyo‐Barea, Andres, Heckel, Tobias, Cuenca, Isabel, Martin, Lucia, Höschle, Carlotta, Müller, Nicole, Vogt, Cornelia, Bischler, Thorsten, Campo, Paula L., Han, Seungbin, Buenache, Natalia, Zhou, Xiang, Bassermann, Florian, Waldschmidt, Johannes, Steinbrunn, Torsten, Rasche, Leo, Stühmer, Thorsten, Martinez‐Lopez, Joaquin, Martin Kortüm, K., Barrio, Santiago

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P840: ASSESSMENT OF CONVENTIONAL TRANSLOCATIONS AND IG REARRANGEMENTS IN THE DIAGNOSIS OF MULTIPLE MYELOMA PATIENTS USING A TARGETED CAPTURE‐HYBRIDIZATION RNA SEQUENCING PANEL by Buenache Cuenda, Natalia, Sánchez, Ricardo, Giménez Sánchez, Alicia, Carneros Blanco, Laura, Alonso Fernández, Rafael, Pina, José María Sánchez, Rapado Martínez, Inmaculada, Ayala Diaz, Rosa, Martinez‐Lopez, Joaquín, Rosa, Juan Manuel Rosa

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Genetic Alterations in Members of the Proteasome 26S Subunit, AAA-Atpase (PSMC) Gene Family Transmit Proteasome Inhibitor Resistance in Multiple Myeloma By Impacting the ADP/ATP Bi... by Haertle, Larissa, Cuesta Hernandez, Hipolito Nicolas, Buenache, Natalia Sofia, Simicek, Michal, Snaurova, Renata, Rapado, Inmaculada, Martinez, Nerea, López-Muñoz, Nieves, Sanchez-Pina, Jose Maria, Colmenares, Rafael, Sanchez-Beato, Margarita, Piris, Miguel Angel, Plaza Menacho, Ivan, Kemal Samur, Mehmet, Munshi, Nikhil C, Ayala, Rosa, Kortuem, K. Martin, Barrio, Santiago, Martinez-Lopez, Joaquin

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Identification of Immunoglobulin Gene Rearrangement Biomarkers in Multiple Myeloma through cfDNA-Based Liquid Biopsy Using tchDNA-Seq by Buenache, Natalia, Sánchez-delaCruz, Andrea, Cuenca, Isabel, Giménez, Alicia, Moreno, Laura, Martínez-López, Joaquín, Rosa-Rosa, Juan Manuel

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P-165 Advanced circulating tumor DNA (ctDNA) Profiling: Enhancing Non-Invasive Detection and Characterization of Measurable Residual Disease (MRD) in Multiple Myeloma (MM) by Buenache, Natalia, Martín-Muñoz, Alejandro, Ruiz-Heredia, Yanira, Lasa, Marta, Notarfranchi, Laura, Gonzalez, Carmen, Cedena, Maria Teresa, Barrio, Santiago, Calasanz, Maria Jose, Manteca, María-Victoria Mateos, Rosiñol, Laura, Lahuerta, Juan Jose, Blade, Joan, San-Miguel, Jesús, Puig, Noemi, Paiva, Bruno, Martínez-Lopez, Joaquín

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Genetic Alterations in Members of the Proteasome 26S Subunit, AAA-ATPase ( PSMC ) Gene Family in the Light of Proteasome Inhibitor Resistance in Multiple Myeloma by Haertle, Larissa, Buenache, Natalia, Cuesta Hernández, Hipólito Nicolás, Simicek, Michal, Snaurova, Renata, Rapado, Inmaculada, Martinez, Nerea, López-Muñoz, Nieves, Sánchez-Pina, José María, Munawar, Umair, Han, Seungbin, Ruiz-Heredia, Yanira, Colmenares, Rafael, Gallardo, Miguel, Sanchez-Beato, Margarita, Piris, Miguel Angel, Samur, Mehmet Kemal, Munshi, Nikhil C, Ayala, Rosa, Kortüm, Klaus Martin, Barrio, Santiago, Martínez-López, Joaquín

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NGS-Based Molecular Karyotyping of Multiple Myeloma: Results from the GEM12 Clinical Trial by Rosa-Rosa, Juan Manuel, Cuenca, Isabel, Medina, Alejandro, Vázquez, Iria, Sánchez-delaCruz, Andrea, Buenache, Natalia, Sánchez, Ricardo, Jiménez, Cristina, Rosiñol, Laura, Gutiérrez, Norma C., Ruiz-Heredia, Yanira, Barrio, Santiago, Oriol, Albert, Martin-Ramos, Maria-Luisa, Blanchard, María-Jesús, Ayala, Rosa, Ríos-Tamayo, Rafael, Sureda, Anna, Hernández, Miguel-Teodoro, de la Rubia, Javier, Alkorta-Aranburu, Gorka, Agirre, Xabier, Bladé, Joan, Mateos, María-Victoria, Lahuerta, Juan-José, San-Miguel, Jesús F., Calasanz, María-José, Garcia-Sanz, Ramón, Martínez-Lopez, Joaquín

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Intracytoplasmatic BCMA Point Mutation and Teclistamab Resistance: Genomic Assessment of a Multidrug-Resistant Multiple Myeloma Patient by Buenache Cuenda, Natalia, Cuesta Hernández, Hipolito Nicolas, Giménez Sánchez, Alicia, Carneros Blanco, Laura, Rosa-Rosa, Juan Manuel, Ruiz-Heredia, Yanira, Revilla, Enrique, Han, Seungbin, Munawar, Umair, Rapado, Inmaculada, Ayala, Rosa, Kortüm, K. Martin, Valeri, Antonio, Barrio, Santiago, Martinez Lopez, Joaquin, Haertle, Larissa

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Minimally Invasive Assessment of Measurable Residual Disease (MRD) in Multiple Myeloma (MM) by Gonzalez, Carmen, Lasa, Marta, Notarfranchi, Laura, Agullo, Cristina, Buenache Cuenda, Natalia, Zherniakova, Anastasiia, Castro, Sergio, Pérez, José Juan, Gonzalez-Calle, Veronica, Cedena Romero, Maria Teresa, Barrio, Santiago, Martín-Muñoz, Alejandro, Burgos, Leire, Alignani, Diego, Calasanz, Maria Jose, Rodriguez Otero, Paula, Rosiñol, Laura, De Arriba, Felipe, Ocio, Enrique M, Rocafiguera, Albert Oriol, Palomera, Luis, González-Montes, Yolanda, Sureda Balari, Anna Maria, Hernandez Garcia, Miguel Teodoro, Clavero Sanchez, Maria Esther, Ibanez Garcia, Angela, Gomez, Clara, Orfao, Alberto, Mateos, Maria Victoria, Lahuerta Palacios, Juan Jose, Bladé, Joan, San-Miguel, Jesus, Martinez-Lopez, Joaquin, Puig, Noemi, Paiva, Bruno

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