A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo by Xie, Stanley C, Tai, Chia-Wei, Morton, Craig J, Ma, Liting, Huang, Shih-Chung, Wittlin, Sergio, Du, Yawei, Hu, Yongbo, Dogovski, Con, Salimimarand, Mina, Griffin, Robert, England, Dylan, de la Cruz, Elisa, Deni, Ioanna, Yeo, Tomas, Burkhard, Anna Y, Striepen, Josefine, Schindler, Kyra A, Crespo, Benigno, Gamo, Francisco J, Khandokar, Yogesh, Hutton, Craig A, Rabie, Tayla, Birkholtz, Lyn-Marié, Famodimu, Mufuliat T, Delves, Michael J, Bolsher, Judith, Koolen, Karin M J, van der Laak, Rianne, Aguiar, Anna C C, Pereira, Dhelio B, Guido, Rafael V C, Creek, Darren J, Fidock, David A, Dick, Lawrence R, Brand, Stephen L, Gould, Alexandra E, Langston, Steven, Griffin, Michael D W, Tilley, Leann

Get full text

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness by Mok, Sachel, Yeo, Tomas, Hong, Davin, Shears, Melanie J, Ross, Leila S, Ward, Kurt E, Dhingra, Satish K, Kanai, Mariko, Bridgford, Jessica L, Tripathi, Abhai K, Mlambo, Godfree, Burkhard, Anna Y, Ansbro, Megan R, Fairhurst, Kate J, Gil-Iturbe, Eva, Park, Heekuk, Rozenberg, Felix D, Kim, Jonathan, Mancia, Filippo, Fairhurst, Rick M, Quick, Matthias, Uhlemann, Anne-Catrin, Sinnis, Photini, Fidock, David A

Get full text

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission by Gomez-Gonzalez, Paula-Josefina, Gupta, Antima, Drought, Laura G, Patel, Avnish, Okombo, John, van der Watt, Mariëtte, Walker-Gray, Ryan, Schindler, Kyra A, Burkhard, Anna Y, Yeo, Tomas, Narwal, Sunil K, Bloxham, Talia S, Flueck, Christian, Walker, Eloise M, Rey, Joshua A, Fairhurst, Kate J, Reader, Janette, Park, Heekuk, Pollard, Harry G, Stewart, Lindsay B, Brandner-Garrod, Luke, Kristan, Mojca, Sterk, Geert-Jan, van Nuland, Youri M, Manko, Emilia, van Schalkwyk, Donelly A, Zheng, Yang, Leurs, Rob, Dechering, Koen J, Aguiar, Anna Caroline C, Guido, Rafael V C, Pereira, Dhelio B, Tumwebaze, Patrick K, Nosbya, Samuel L, Rosenthal, Philip J, Cooper, Roland A, Palmer, Mike, Parkinson, Tanya, Burrows, Jeremy N, Uhlemann, Anne-Catrin, Birkholtz, Lyn-Marié, Small-Saunders, Jennifer L, Duffy, James, Fidock, David A, Brown, Alan, Gardner, Mark, Baker, David A

Get full text

Anti-plasmodial limonoids from Khaya anthotheca (Welw.) C.DC by Obbo, Christopher J.D., Mwangi, Elizabeth M., Kariuki, Samuel T., Gathirwa, Jeremiah W., Fairhurst, Kate J., Burkhard, Anna Y., Fidock, David A., Sadgrove, Nicholas, Langat, Moses K., Mas-Claret, Eduard, Mulholland, Dulcie A.

Get full text

Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on CFTR Function in Patients with Cystic Fibrosis and One or Two F508del Alleles by Graeber, Simon Y, Vitzthum, Constanze, Pallenberg, Sophia T, Naehrlich, Lutz, Stahl, Mirjam, Rohrbach, Alexander, Drescher, Marika, Minso, Rebecca, Ringshausen, Felix C, Rueckes-Nilges, Claudia, Klajda, Jan, Berges, Julian, Yu, Yin, Scheuermann, Heike, Hirtz, Stephanie, Sommerburg, Olaf, Dittrich, Anna-Maria, Tümmler, Burkhard, Mall, Marcus A

Get full text

Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Lung Clearance Index and Magnetic Resonance Imaging in Patients with Cystic Fibrosis and One or Two F508del Alleles by Graeber, Simon Y, Renz, Diane M, Stahl, Mirjam, Pallenberg, Sophia T, Sommerburg, Olaf, Naehrlich, Lutz, Berges, Julian, Dohna, Martha, Ringshausen, Felix C, Doellinger, Felix, Vitzthum, Constanze, Röhmel, Jobst, Allomba, Christine, Hämmerling, Susanne, Barth, Sandra, Rückes-Nilges, Claudia, Wielpütz, Mark O, Hansen, Gesine, Vogel-Claussen, Jens, Tümmler, Burkhard, Mall, Marcus A, Dittrich, Anna-Maria

Get full text

C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages by Hoeffel, Guillaume, Chen, Jinmiao, Lavin, Yonit, Low, Donovan, Almeida, Francisca F., See, Peter, Beaudin, Anna E., Lum, Josephine, Low, Ivy, Forsberg, E. Camilla, Poidinger, Michael, Zolezzi, Francesca, Larbi, Anis, Ng, Lai Guan, Chan, Jerry K.Y., Greter, Melanie, Becher, Burkhard, Samokhvalov, Igor M., Merad, Miriam, Ginhoux, Florent

Get full text

Endothelial overexpression of LOX-1 increases plaque formation and promotes atherosclerosis in vivo by Akhmedov, Alexander, Rozenberg, Izabela, Paneni, Francesco, Camici, Giovanni G, Shi, Yi, Doerries, Carola, Sledzinska, Anna, Mocharla, Pavani, Breitenstein, Alexander, Lohmann, Christine, Stein, Sokrates, von Lukowicz, Tobias, Kurrer, Michael O, Borén, Jan, Becher, Burkhard, Tanner, Felix C, Landmesser, Ulf, Matter, Christian M, Lüscher, Thomas F

Get full text

Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease by Matsubara, Etsuro, Bryant‐Thomas, Tara, Pacheco Quinto, Javier, Henry, Tracey L., Poeggeler, Burkhard, Herbert, Donald, Cruz‐Sanchez, Felix, Chyan, Yau‐Jan, Smith, Mark A., Perry, George, Shoji, Mikio, Abe, Koji, Leone, Anna, Grundke‐Ikbal, Inge, Wilson, Glen L., Ghiso, Jorge, Williams, Christina, Refolo, Lorenzo M., Pappolla, Miguel A.

Get full text

Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease by Matsubara, Etsuro, Bryant‐Thomas, Tara, Pacheco, Javier, Henry, Tracey L., Poeggeler, Burkhard, Herbert, Donald, Cruz‐Sanchez, Felix, Chyan, Yau‐Jan, Smith, Mark A., Perry, George, Chain, Daniel G., Neria, Eyal, Shoji, Mikio, Abe, Koji, Leone, Anna, Grundke‐Iqbal, Inge, Wilson, Glen L., Ghiso, Jorge, Williams, Christina, Refolo, Lorenzo M., Pappolla, Miguel A.

Get full text