ALT neuroblastoma chemoresistance due to telomere dysfunction-induced ATM activation is reversible with ATM inhibitor AZD0156 by Koneru, Balakrishna, Farooqi, Ahsan, Nguyen, Thinh H, Chen, Wan Hsi, Hindle, Ashly, Eslinger, Cody, Makena, Monish Ram, Burrow, Trevor A, Wilson, Joanne, Smith, Aaron, Pilla Reddy, Venkatesh, Cadogan, Elaine, Durant, Stephen T, Reynolds, C Patrick

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Alternative Lengthening of Telomeres in Cancer Confers a Vulnerability to Reactivation of p53 Function by Macha, Shawn J, Koneru, Balakrishna, Burrow, Trevor A, Zhu, Charles, Savitski, Dzmitry, Rahman, Rakhshanda L, Ronaghan, Catherine A, Nance, Jonas, McCoy, Kristyn, Eslinger, Cody, Reynolds, C Patrick

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Prevalence of alternative lengthening of telomeres in pediatric sarcomas determined by the telomeric DNA C-circle assay by Burrow, Trevor A, Koneru, Balakrishna, Macha, Shawn J, Sun, Wenyue, Barr, Frederic G, Triche, Timothy J, Reynolds, C Patrick

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HGG-48. THE BLOOD-BASED TELOMERIC DNA C-CIRCLE ASSAY CAN DETECT ALTERNATIVE LENGTHENING OF TELOMERES (ALT) IN PEDIATRIC HIGH-GRADE GLIOMAS by Lehman, Tenley E, Deal, Jenna L, Lee, Jihyun, Foster, Jessica B, Koptyra, Mateusz P, Burrow, Trevor A, Koneru, Balakrishna, Cole, Kristina A, Reynolds, C Patrick

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Abstract 6228: APR-246, which restores p53 function, is highly active against alternative lengthening of telomere (ALT) cell lines and PDXs by Macha, Shawn J., Koneru, Balakrishna, Burrow, Trevor, Zhu, Charles, Savitski, Dzmitry, Nance, Jonas, McCoy, Kristyn, Eslinger, Cody, Reynolds, C Patrick

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Whole-genome sequencing of patients with rare diseases in a national health system by Turro, Ernest, Astle, William J., Megy, Karyn, Gräf, Stefan, Greene, Daniel, Shamardina, Olga, Allen, Hana Lango, Sanchis-Juan, Alba, Frontini, Mattia, Thys, Chantal, Stephens, Jonathan, Mapeta, Rutendo, Burren, Oliver S., Downes, Kate, Haimel, Matthias, Tuna, Salih, Deevi, Sri V. V., Aitman, Timothy J., Bennett, David L., Calleja, Paul, Carss, Keren, Caulfield, Mark J., Chinnery, Patrick F., Dixon, Peter H., Gale, Daniel P., James, Roger, Koziell, Ania, Laffan, Michael A., Levine, Adam P., Maher, Eamonn R., Markus, Hugh S., Morales, Joannella, Morrell, Nicholas W., Mumford, Andrew D., Ormondroyd, Elizabeth, Rankin, Stuart, Rendon, Augusto, Richardson, Sylvia, Roberts, Irene, Roy, Noemi B. A., Saleem, Moin A., Smith, Kenneth G. C., Stark, Hannah, Tan, Rhea Y. Y., Themistocleous, Andreas C., Thrasher, Adrian J., Watkins, Hugh, Webster, Andrew R., Wilkins, Martin R., Williamson, Catherine, Whitworth, James, Humphray, Sean, Bentley, David R., Kingston, Nathalie, Walker, Neil, Bradley, John R., Ashford, Sofie, Penkett, Christopher J., Freson, Kathleen, Stirrups, Kathleen E., Raymond, F. Lucy, Ouwehand, Willem H.

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An evaluation of the effect of an angiotensin-converting enzyme inhibitor on the growth rate of small abdominal aortic aneurysms: a randomized placebo-controlled trial (AARDVARK) by Bicknell, Colin D, Kiru, Gaia, Falaschetti, Emanuela, Powell, Janet T, Poulter, Neil R

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The clinical relevance of MOG antibody testing in cerebrospinal fluid by Reynolds, Molly, Tan, Irene, Nguyen, Kristy, Merheb, Vera, Lee, Fiona X Z, Trewin, Benjamin P, Lerch, Magdalena, Shah, Snehal, Wolfe, Nigel, Buzzard, Katherine, Lechner-Scott, Jeannette, Fabis-Pedrini, Marzena, Fok, Anthony, John, Nevin, Kneebone, Chris, Yiannikas, Con, Brown, David A, Kermode, Allan G, Reddel, Stephen, Dale, Russell C, Brilot, Fabienne, Ramanathan, Sudarshini

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