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AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity
by
Blair, Jessica M. A.
,
Bavro, Vassiliy N.
,
Ricci, Vito
,
Modi, Niraj
,
Cacciotto, Pierpaolo
,
Kleinekathӧfer, Ulrich
,
Ruggerone, Paolo
,
Vargiu, Attilio V.
,
Baylay, Alison J.
,
Smith, Helen E.
,
Brandon, Yvonne
,
Galloway, David
,
Piddock, Laura J. V.
Published in
Proceedings of the National Academy of Sciences - PNAS
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Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA
by
Cacciotto, Pierpaolo
,
Basciu, Andrea
,
Oliva, Francesco
,
Malloci, Giuliano
,
Zacharias, Martin
,
Ruggerone, Paolo
,
Vargiu, Attilio V.
Published in
Computational and structural biotechnology journal
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Computational And Structural Biotechnology Journal
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Proceedings Of The National Academy Of Sciences
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Proceedings Of The National Academy Of Sciences Of The United States Of America
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Acrb
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Amino Acid Substitution
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Anti-Bacterial Agents - Pharmacology
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Antimicrobial Resistance
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Bacterial Proteins - Genetics
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Ciprofloxacin - Pharmacology
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Doxorubicin - Chemistry
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Drug Resistance, Multiple, Bacterial - Drug Effects
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Escherichia Coli - Drug Effects
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Jstor Archival Journals And Primary Sources Collection
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