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Search Results - Chassagnon, Irène R.
Search Results - Chassagnon, Irène R.
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Revealing molecular determinants governing mambalgin-3 pharmacology at acid-sensing ion channel 1 variants
by
Cristofori-Armstrong, Ben
,
Budusan, Elena
,
Smith, Jennifer J.
,
Reynaud, Steve
,
Voll, Kerstin
,
Chassagnon, Irène R.
,
Durek, Thomas
,
Rash, Lachlan D.
Published in
Cellular and molecular life sciences : CMLS
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The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: Importance of interactions at the channel subunit interface and potential for engineer...
by
Cristofori-Armstrong, Ben
,
Saez, Natalie J.
,
Chassagnon, Irène R.
,
King, Glenn F.
,
Rash, Lachlan D.
Published in
Biochemical pharmacology
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PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a
by
McCarthy, Claudia A.
,
Rash, Lachlan D.
,
Chassagnon, Irène R.
,
King, Glenn F.
,
Widdop, Robert E.
Published in
Neuropharmacology
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A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a
by
Saez, Natalie J
,
Mobli, Mehdi
,
Bieri, Michael
,
Chassagnon, Irène R
,
Malde, Alpeshkumar K
,
Gamsjaeger, Roland
,
Mark, Alan E
,
Gooley, Paul R
,
Rash, Lachlan D
,
King, Glenn F
Published in
Molecular pharmacology
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Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid‐sensing ion channel 1a
by
Saez, Natalie J
,
Deplazes, Evelyne
,
Cristofori‐Armstrong, Ben
,
Chassagnon, Irène R
,
Lin, Xiaozhen
,
Mobli, Mehdi
,
Mark, Alan E
,
Rash, Lachlan D
,
King, Glenn F
Published in
British journal of pharmacology
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Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a
by
Chassagnon, Irène R.
,
McCarthy, Claudia A.
,
Chin, Yanni K.-Y.
,
Pineda, Sandy S.
,
Keramidas, Angelo
,
Mobli, Mehdi
,
Pham, Vi
,
De Silva, T. Michael
,
Lynch, Joseph W.
,
Widdop, Robert E.
,
Rash, Lachlan D.
,
King, Glenn F.
Published in
Proceedings of the National Academy of Sciences - PNAS
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Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
by
Piper, Sarah J
,
Brillault, Lou
,
Rothnagel, Rosalba
,
Croll, Tristan I
,
Box, Joseph K
,
Chassagnon, Irene
,
Scherer, Sebastian
,
Goldie, Kenneth N
,
Jones, Sandra A
,
Schepers, Femke
,
Hartley-Tassell, Lauren
,
Ve, Thomas
,
Busby, Jason N
,
Dalziel, Julie E
,
Lott, J Shaun
,
Hankamer, Ben
,
Stahlberg, Henning
,
Hurst, Mark R H
,
Landsberg, Michael J
Published in
Nature communications
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The ABC toxin complex from Yersinia entomophaga can package three different cytotoxic components expressed from distinct genetic loci in an unfolded state: the structures of both s...
by
Busby, Jason N
,
Trevelyan, Sarah
,
Pegg, Cassandra L
,
Kerr, Edward D
,
Schulz, Benjamin L
,
Chassagnon, Irene
,
Landsberg, Michael J
,
Weston, Mitchell K
,
Hurst, Mark R H
,
Lott, J Shaun
Published in
IUCrJ
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Acid Sensing Ion Channels - Metabolism
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Xenopus Laevis
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Acid-Sensing Ion Channel 1A
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Acidity
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