High-Throughput Biophysical Analysis of Protein Therapeutics to Examine Interrelationships Between Aggregate Formation and Conformational Stability by Chaudhuri, Rajoshi, Cheng, Yuan, Middaugh, C. Russell, Volkin, David B.

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Long term stability of a HIV-1 neutralizing monoclonal antibody using isothermal calorimetry by Clarkson, Benjamin R., Chaudhuri, Rajoshi, Schön, Arne, Cooper, Jonathan W., Kueltzo, Lisa, Freire, Ernesto

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Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody by Kwon, Young D., Chuang, Gwo-Yu, Zhang, Baoshan, Bailer, Robert T., Doria-Rose, Nicole A., Gindin, Tatyana S., Lin, Bob, Louder, Mark K., McKee, Krisha, O’Dell, Sijy, Pegu, Amarendra, Schmidt, Stephen D., Asokan, Mangaiarkarasi, Chen, Xuejun, Choe, Misook, Georgiev, Ivelin S., Jin, Vivian, Pancera, Marie, Rawi, Reda, Wang, Keyun, Chaudhuri, Rajoshi, Kueltzo, Lisa A., Manceva, Slobodanka D., Todd, John-Paul, Scorpio, Diana G., Kim, Mikyung, Reinherz, Ellis L., Wagh, Kshitij, Korber, Bette M., Connors, Mark, Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.

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Removal of variable domain N -linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies by Chuang, Gwo-Yu, Asokan, Mangaiarkarasi, Ivleva, Vera B, Pegu, Amarendra, Yang, Eun Sung, Zhang, Baoshan, Chaudhuri, Rajoshi, Geng, Hui, Lin, Bob C, Louder, Mark K, McKee, Krisha, O'Dell, Sijy, Wang, Hairong, Zhou, Tongqing, Doria-Rose, Nicole A, Kueltzo, Lisa A, Lei, Q Paula, Mascola, John R, Kwong, Peter D

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Optimization of Formulation Conditions for Broadly Neutralizing Antibodies (bnAb): Utilizing Isothermal Chemical Denaturation as a High-throughput Screening Method by Fleischman, Marianna L., Chaudhuri, Rajoshi, Caringal, Ria T., Kueltzo, Lisa, Cheng, K.C., Arnold, Frank

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An influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults by Widge, Alicia T, Hofstetter, Amelia R, Houser, Katherine V, Awan, Seemal F, Chen, Grace L, Burgos Florez, Maria C, Berkowitz, Nina M, Mendoza, Floreliz, Hendel, Cynthia S, Holman, LaSonji A, Gordon, Ingelise J, Apte, Preeti, Liang, C Jason, Gaudinski, Martin R, Coates, Emily E, Strom, Larisa, Wycuff, Diane, Vazquez, Sandra, Stein, Judy A, Gall, Jason G, Adams, William C, Carlton, Kevin, Gillespie, Rebecca A, Creanga, Adrian, Crank, Michelle C, Andrews, Sarah F, Castro, Mike, Serebryannyy, Leonid A, Narpala, Sandeep R, Hatcher, Christian, Lin, Bob C, O'Connell, Sarah, Freyn, Alec W, Rosado, Victoria C, Nachbagauer, Raffael, Palese, Peter, Kanekiyo, Masaru, McDermott, Adrian B, Koup, Richard A, Dropulic, Lesia K, Graham, Barney S, Mascola, John R, Ledgerwood, Julie E

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Safety and immunogenicity of a trivalent virus-like particle vaccine against western, eastern, and Venezuelan equine encephalitis viruses: a phase 1, open-label, dose-escalation, r... by Coates, Emily E, Edupuganti, Srilatha, Chen, Grace L, Happe, Myra, Strom, Larisa, Widge, Alicia, Florez, Maria Burgos, Cox, Josephine H, Gordon, Ingelise, Plummer, Sarah, Ola, Abidemi, Yamshchikov, Galina, Andrews, Charla, Curate-Ingram, Sharon, Morgan, Patricia, Nagar, Shashi, Collins, Matthew H, Bray, Amy, Nguyen, Thuy, Stein, Judy, Case, Christopher L, Kaltovich, Florence, Wycuff, Diane, Liang, C Jason, Carlton, Kevin, Vazquez, Sandra, Mascola, John R, Ledgerwood, Julie E

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Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen by Ou, Li, Kong, Wing-Pui, Chuang, Gwo-Yu, Ghosh, Mridul, Gulla, Krishana, O’Dell, Sijy, Varriale, Joseph, Barefoot, Nathan, Changela, Anita, Chao, Cara W., Cheng, Cheng, Druz, Aliaksandr, Kong, Rui, McKee, Krisha, Rawi, Reda, Sarfo, Edward K., Schön, Arne, Shaddeau, Andrew, Tsybovsky, Yaroslav, Verardi, Raffaello, Wang, Shuishu, Wanninger, Timothy G., Xu, Kai, Yang, Gengcheng J., Zhang, Baoshan, Zhang, Yaqiu, Zhou, Tongqing, Arnold, Frank J., Doria-Rose, Nicole A., Lei, Q. Paula, Ryan, Edward T., Vann, Willie F., Mascola, John R., Kwong, Peter D.

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Low-dose intravenous and subcutaneous CIS43LS monoclonal antibody for protection against malaria (VRC 612 Part C): a phase 1, adaptive trial by Lyke, Kirsten E, Berry, Andrea A, Mason, Kaitlin, Idris, Azza H, O'Callahan, Mark, Happe, Myra, Strom, Larisa, Berkowitz, Nina M, Guech, Mercy, Hu, Zonghui, Castro, Mike, Basappa, Manjula, Wang, Lu, Low, Kwang, Holman, LaSonji A, Mendoza, Floreliz, Gordon, Ingelise J, Plummer, Sarah H, Trofymenko, Olga, Strauss, Kathleen S, Joshi, Sudhaunshu, Shrestha, Biraj, Adams, Matthew, Chagas, Andrezza Campos, Murphy, Jittawadee R, Stein, Judy, Hickman, Somia, McDougal, Andrew, Lin, Bob, Narpala, Sandeep R, Vazquez, Sandra, Serebryannyy, Leonid, McDermott, Adrian, Gaudinski, Martin R, Capparelli, Edmund V, Coates, Emily E, Wu, Richard L, Ledgerwood, Julie E, Dropulic, Lesia K, Seder, Robert A, Young, Cheryl, Boyce, Colleen, Winkler, Jennifer, Holian, Susan, Greenberg, Nancy, George, Shirley, Kwon, Alyson, Dorsey, Brenda, Da Costa, Ana Raquel, Witt, William, Grays, Daryl, Gapasin, Arren, Bernal, Paula, Floyd, Jeffrey, Goldstein, Eric, Howe, Leslie, Lee, Myounghee, Marron, Jennifer, Brooks, Kelly, Turek, Lisa, Farley, Patricia, Frels, Shantel, Booth, Delores, Gall, Jason, Carlton, Kevin, Albright, Gabriela, Amharref, Nadia, Atallah, Kandace, Banappagari, Sashikanth, Bastani, Niutish, Blackstock, Daniel, Boonyaratanakornkit, Bobby, Carey, Elizabeth, Charlton, Adam, Chaudhuri, Rajoshi, Caringal, Alegria M., Chen, Mingzhong, Chen, Peifeng, Cheng, Wei, Gowetski, Daniel, Gulla, Krishana, Hastings, Erica, Horwitz, Joe, Ivleva, Vera, Kordella, Dan, Kueltzo, Lisa A., Lagler, Sara, Le, Matt, Lee, James, Lei, Paula, Li, Yile, Nagy, Attila, Patel, Aakash, Runsewe, Peyi, Shadrick, Will, Shetty, Shamitha, Wang, Hairong, Webber, Calvin, Vejzagic, Farah, Yang, Yoo-Jung

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Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant by Francica, Joseph R, Lynn, Geoffrey M, Laga, Richard, Joyce, M. Gordon, Ruckwardt, Tracy J, Morabito, Kaitlyn M, Chen, Man, Chaudhuri, Rajoshi, Zhang, Baoshan, Sastry, Mallika, Ko, Kiyoon, Choe, Misook, Pechar, Michal, Georgiev, Ivelin S, Kueltzo, Lisa A, Seymour, Leonard W, Mascola, John R, Kwong, Peter D, Graham, Barney S, Seder, Robert A

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Predicting the Stability of Monoclonal Antibodies at High Concentration Formulations by Konrath, Kylie M., Nugent, Sean, Chamberlain, Amy L., Ragunathan, Rahul, Hsu, Vasha, Wang, Hairong, Fleischman, Marianna L., Ihms, Elihu, Chaudhuri, Rajoshi, Mančeva, Slobodanka M., Kueltzo, Lisa A., Cheng, K.C., Arnold, Frank

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Effect of acrylodan conjugation and forced oxidation on the structural integrity, conformational stability, and binding activity of a glucose binding protein SM4 used in a prototyp... by Hickey, John M., Sahni, Neha, Chaudhuri, Rajoshi, D'Souza, Ajit, Metters, Andrew, Joshi, Sangeeta B., Russell Middaugh, C., Volkin, David B.

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Preformulation Characterization, Stabilization, and Formulation Design for the Acrylodan-Labeled Glucose-Binding Protein SM4-AC by Sahni, Neha, Chaudhuri, Rajoshi, Hickey, John M., Manikwar, Prakash, D’Souza, Ajit, Metters, Andrew, Joshi, Sangeeta B., Middaugh, C. Russell, Volkin, David B.

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Phase 1 dose-escalation trial evaluating a group 2 influenza hemagglutinin stabilized stem nanoparticle vaccine by Casazza, Joseph P., Hofstetter, Amelia R., Costner, Pamela J. M., Holman, LaSonji A., Hendel, Cynthia S., Widge, Alicia T., Wu, Richard L., Whalen, William R., Cunningham, Jennifer, Arthur, Anita, Wang, Xiaolin, Ola, Abidemi, Saunders, Jamie, Mendoza, Floreliz, Novik, Laura, Burgos Florez, Maria C., Ortega-Villa, Ana M., Apte, Preeti J., Strom, Larisa, Wang, Lu, Imam, Marjaan, Basappa, Manjula, Naisan, Mursal, Castro, Mike, Trost, Jessica F., Narpala, Sandeep R., Vanderven, Hillary A., Yamshchikov, Galina V., Berkowitz, Nina M., Gordon, Ingelise J., Plummer, Sarah H., Wycuff, Diane L., Vazquez, Sandra, Gillespie, Rebecca A., Creanga, Adrian, Adams, William C., Carlton, Kevin, Gall, Jason G., McDermott, Adrian B., Serebryannyy, Leonid A., Houser, Katherine V., Koup, Richard A., Graham, Barney S., Ledgerwood, Julie E., Mascola, John R., Pierson, Theodore C., Andrews, Sarah F., Kanekiyo, Masaru, Dropulic, Lesia K.

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Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody by Kwon, Young D., Chuang, Gwo-Yu, Zhang, Baoshan, Bailer, Robert T., Doria-Rose, Nicole A., Gindin, Tatyana S., Lin, Bob, Louder, Mark K., McKee, Krisha, O’Dell, Sijy, Pegu, Amarendra, Schmidt, Stephen D., Asokan, Mangaiarkarasi, Chen, Xuejun, Choe, Misook, Georgiev, Ivelin S., Jin, Vivian, Pancera, Marie, Rawi, Reda, Wang, Keyun, Chaudhuri, Rajoshi, Kueltzo, Lisa A., Manceva, Slobodanka D., Todd, John-Paul, Scorpio, Diana G., Kim, Mikyung, Reinherz, Ellis L., Wagh, Kshitij, Korber, Bette M., Connors, Mark, Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.

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Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies by Chuang, Gwo-Yu, Asokan, Mangaiarkarasi, Ivleva, Vera B., Pegu, Amarendra, Yang, Eun Sung, Zhang, Baoshan, Chaudhuri, Rajoshi, Geng, Hui, Lin, Bob C., Louder, Mark K., McKee, Krisha, O'Dell, Sijy, Wang, Hairong, Zhou, Tongqing, Doria-Rose, Nicole A., Kueltzo, Lisa A., Lei, Q. Paula, Mascola, John R., Kwong, Peter D.

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