Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy by Incio, Joao, Liu, Hao, Suboj, Priya, Chin, Shan M, Chen, Ivy X, Pinter, Matthias, Ng, Mei R, Nia, Hadi T, Grahovac, Jelena, Kao, Shannon, Babykutty, Suboj, Huang, Yuhui, Jung, Keehoon, Rahbari, Nuh N, Han, Xiaoxing, Chauhan, Vikash P, Martin, John D, Kahn, Julia, Huang, Peigen, Desphande, Vikram, Michaelson, James, Michelakos, Theodoros P, Ferrone, Cristina R, Soares, Raquel, Boucher, Yves, Fukumura, Dai, Jain, Rakesh K

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Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma by Shigeta, Kohei, Matsui, Aya, Kikuchi, Hiroto, Klein, Sebastian, Mamessier, Emilie, Chen, Ivy X, Aoki, Shuichi, Kitahara, Shuji, Inoue, Koetsu, Shigeta, Ayako, Hato, Tai, Ramjiawan, Rakesh R, Staiculescu, Daniel, Zopf, Dieter, Fiebig, Lukas, Hobbs, Gabriela S, Quaas, Alexander, Dima, Simona, Popescu, Irinel, Huang, Peigen, Munn, Lance L, Cobbold, Mark, Goyal, Lipika, Zhu, Andrew X, Jain, Rakesh K, Duda, Dan G

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Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model by Li, Wende, Li, Sen, Chen, Ivy X, Liu, Yujiao, Ramjiawan, Rakesh R, Leung, Chi-Ho, Gerweck, Leo E, Fukumura, Dai, Loeffler, Jay S, Jain, Rakesh K, Duda, Dan G, Huang, Peigen

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Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer by Chen, Ivy X., Chauhan, Vikash P., Posada, Jessica, Ng, Mei R., Wu, Michelle W., Adstamongkonkul, Pichet, Huang, Peigen, Lindeman, Neal, Langer, Robert, Jain, Rakesh K.

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Lymph node effective vascular permeability and chemotherapy uptake by Meijer, Eelco F. J., Blatter, Cedric, Chen, Ivy X., Bouta, Echoe, Jones, Dennis, Pereira, Ethel R., Jung, Keehoon, Vakoc, Benjamin J., Baish, James W., Padera, Timothy P.

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Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy by Chauhan, Vikash P., Chen, Ivy X., Tong, Rong, Ng, Mei Rosa, Martin, John D., Naxerova, Kamila, Wu, Michelle W., Huang, Peigen, Boucher, Yves, Kohane, Daniel S., Langer, Robert, Jain, Rakesh K.

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Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy by Ho, William W., Gomes-Santos, Igor L., Aoki, Shuichi, Datta, Meenal, Kawaguchi, Kosuke, Talele, Nilesh P., Roberge, Sylvie, Ren, Jun, Liu, Hao, Chen, Ivy X., Andersson, Patrik, Chatterjee, Sampurna, Kumar, Ashwin S., Amoozgar, Zohreh, Zhang, Qixian, Huang, Peigen, Ng, Mei Rosa, Chauhan, Vikash P., Xu, Lei, Duda, Dan G., Clark, Jeffrey W., Pittet, Mikael J., Fukumura, Dai, Jain, Rakesh K.

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A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade by Chen, Ivy X., Newcomer, Kathleen, Pauken, Kristen E., Juneja, Vikram R., Naxerova, Kamila, Wu, Michelle W., Pinter, Matthias, Sen, Debattama R., Singer, Meromit, Sharpe, Arlene H., Jain, Rakesh K.

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Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models by Datta, Meenal, Chatterjee, Sampurna, Perez, Elizabeth M, Gritsch, Simon, Roberge, Sylvie, Duquette, Mark, Chen, Ivy X, Naxerova, Kamila, Kumar, Ashwin S, Ghosh, Mitrajit, Emblem, Kyrre E, Ng, Mei R, Ho, William W, Kumar, Pragya, Krishnan, Shanmugarajan, Dong, Xinyue, Speranza, Maria C, Neagu, Martha R, Iorgulescu, J Bryan, Huang, Raymond Y, Youssef, Gilbert, Reardon, David A, Sharpe, Arlene H, Freeman, Gordon J, Suvà, Mario L, Xu, Lei, Jain, Rakesh K

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Abstract 2744: Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer by Chen, Ivy X., Chauhan, Vikash P., Posada, Jessica, Ng, Mei R., Wu, Michelle, Adstamongkonkul, Pichet, Huang, Peigen, Lindeman, Neal, Langer, Robert, Jain, Rakesh K.

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Abstract PO-097: Addition of losartan to FOLFIRINOX and chemoradiation reduces the expression of pro-invasive and immunosuppressive genes in locally-advanced pancreatic cancer by Boucher, Yves, Posada, Jessica M., Subudhi, Sonu, Kumar, Ashwin S., Chen, Ivy X., Ng, Mei R., Mino-Kenudson, Mari, Talele, Nilesh, Duda, Dan G., Fukumura, Dai, Murphy, Janet E., Clark, Jeffrey W., Ryan, David P., Fernandez-Del Castillo, Carlos, Hong, Theodore S., Jain, Rakesh K.

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Abstract P061: Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits the efficacy of immune checkpoint blockade by Ho, William W., Gomes-Santos, Igor L., Aoki, Shuichi, Datta, Meenal, Kawaguchi, Kosuke, Talele, Nilesh P, Roberge, Sylvie, Ren, Jun, Liu, Hao, Chen, Ivy X, Andersson, Patrik, Chatterjee, Sampurna, Kumar, Ashwin S., Amoozgar, Zohreh, Zhang, Qixian, Huang, Peigen, Ng, Mei Rosa, Chauhan, Vikash P, Xu, Lei, Duda, Dan G., Clark, Jeffrey W., Pittet, Mikael J., Fukumura, Dai, Jain, Rakesh K

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Abstract B89: Dual PD-1 and VEGFR-2 blockade induces vascular normalization and enhances antitumor immune responses in hepatocellular carcinoma by Datta, Meenal, Shigeta, Kohei, Hato, Tai, Kitihara, Shuji, Chen, Ivy X., Matsui, Aya, Kikuchi, Hiroto, Mamessier, Emilie, Aoki, Shuichi, Ramjiawan, Rakesh R., Ochiai, Hiroki, Bardeesy, Nabeel, Huang, Peigen, Jain, Rakesh K., Cobbold, Mark, Zhu, Andrew X., Duda, Dan G.

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Management of cardiac toxicity in patients receiving vascular endothelial growth factor signaling pathway inhibitors by Steingart, Richard M., MD, Bakris, George L., MD, Chen, Helen X., MD, Chen, Ming-Hui, MD, MMSc, Force, Thomas, MD, Ivy, S. Percy, MD, Leier, Carl V., MD, Liu, Glenn, MD, Lenihan, Daniel, MD, Lindenfeld, JoAnn, MD, Maitland, Michael L., MD, PhD, Remick, Scot C., MD, Tang, W.H. Wilson, MD

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Initial Assessment, Surveillance, and Management of Blood Pressure in Patients Receiving Vascular Endothelial Growth Factor Signaling Pathway Inhibitors by Maitland, Michael L., Bakris, George L., Black, Henry R., Chen, Helen X., Durand, Jean-Bernard, Elliott, William J., Ivy, S. Percy, Leier, Carl V., Lindenfeld, JoAnn, Liu, Glenn, Remick, Scot C., Steingart, Richard, Tang, W. H. Wilson

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Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction by Voon, Pei Jye, Chen, Eric X, Chen, Helen X, Lockhart, Albert C, Sahebjam, Solmaz, Kelly, Karen, Vaishampayan, Ulka N, Subbiah, Vivek, Razak, Albiruni R, Renouf, Daniel J, Hotte, Sebastien J, Singh, Arti, Bedard, Philippe L, Hansen, Aaron R, Ivy, S Percy, Wang, Lisa, Stayner, Lee-Anne, Siu, Lillian L, Spreafico, Anna

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A phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503) by Sahebjam, S, Bedard, P L, Castonguay, V, Chen, Z, Reedijk, M, Liu, G, Cohen, B, Zhang, W-J, Clarke, B, Zhang, T, Kamel-Reid, S, Chen, H, Ivy, S P, Razak, A R A, Oza, A M, Chen, E X, Hirte, H W, McGarrity, A, Wang, L, Siu, L L, Hotte, S J

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Dose‐escalation trial of combination dabrafenib, trametinib, and AT13387 in patients with BRAF‐mutant solid tumors by Mooradian, Meghan J., Cleary, James M., Giobbie‐Hurder, Anita, Darville, Lancia N. F., Parikh, Aparna, Buchbinder, Elizabeth I., Cohen, Justine V., Lawrence, Donald P., Shapiro, Geoffrey I., Keer, Harold, Chen, Helen X., Ivy, Susan Percy, Smalley, Keiran S. M., Koomen, John M., Sullivan, Ryan J.

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Social Robots Outdo the Not-So-Social Media for Self-Disclosure: Safe Machines Preferred to Unsafe Humans? by Luo, Rowling L, Zhang, Thea X. Y, Chen, Derrick H.-C, Hoorn, Johan F, Huang, Ivy S

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Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the Global Burden of Disease Study 2015 by Reitsma, Marissa B, Ng, Marie, Abera, Semaw Ferede, Abyu, Gebre Yitayih, Adebiyi, Akindele Olupelumi, Al Alkerwi, Ala'a, Allebeck, Peter, Al-Raddadi, Rajaa Mohammad, Amare, Azmeraw T, Ammar, Walid, Amrock, Stephen Marc, Antonio, Carl Abelardo T, Atnafu, Niguse Tadela, Azzopardi, Peter, Barac, Aleksandra, Barrientos-Gutierrez, Tonatiuh, Bedi, Neeraj, Bell, Brent, Bensenor, Isabela M, Bhala, Neeraj, Bolt, Kaylin, Butt, Zahid, Cercy, Kelly, Christopher, Devasahayam Jesudas, Colomar, Mercedes, Dai, Xiaochen, Dansereau, Emily, Davletov, Kairat, Deribew, Amare, Doyle, Kerrie E, Endries, Aman Yesuf, Ermakov, Sergey Petrovich, Estep, Kara, Farzadfar, Farshad, Fischer, Florian, Friedman, Joseph, Gao, Wayne, Gold, Audra L, Gotay, Carolyn C, Gupta, Rahul, Harb, Hilda L, Hay, Simon I, Horino, Masako, Ileanu, Bogdan Vasile, Jiang, Ying, Khader, Yousef S, Khubchandani, Jagdish, Kinfu, Yohannes, Kopec, Jacek, Kosen, Soewarta, Kotsakis, Georgios A, Krueger, Hans, Leinsalu, Mall, Liu, Shiwei, Lopez, Alan D, Ma, Stefan, El Razek, Hassan Magdy Abd, Majeed, Azeem, Malekzadeh, Reza, Manamo, Wondimu Ayele, Mekonnen, Alemayehu Berhane, Morawska, Lidia, Musa, Kamarul Imran, PA, Mahesh, Park, Eun-Kee, Rahman, Mahfuzar, Rai, Rajesh Kumar, Ram, Usha, Rodriguez, Alina, Sanabria, Juan, Sawhney, Monika, Sawyer, Susan, Schaub, Michael P, Serdar, Berrin, Shaikh, Masood Ali, She, Jun, Shin, Min-Jeong, Shishani, Kawkab, Slepak, Erica Leigh, Soriano, Joan B, Soshnikov, Sergey, Sreeramareddy, Chandrashekhar T, Stranges, Saverio, Subart, Michelle L, Tefera, Worku Mekonnen, Tran, Bach, Tsilimparis, Nikolaos, Violante, Francesco Saverio, Vollset, Stein Emil, Vos, Theo, Weiderpass, Elisabete, Yakob, Bereket, Ye, Penpeng, Yonemoto, Naohiro, Younis, Mustafa Z, El Sayed Zaki, Maysaa, Zhang, Anthony Lin, Zipkin, Ben, Forouzanfar, Mohammad H, Gakidou, Emmanuela

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