Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC by Taylor, M A, Wappett, M, Delpuech, O, Brown, H, Chresta, C M

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Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax:Bcl-2 ratio by CHRESTA, C. M, MASTERS, J. R. W, HICKMAN, J. A

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Relationship between topoisomerase II level and chemosensitivity in human tumor cell lines by FRY, A. M, CHRESTA, C. M, DAVIES, S. M, WALKER, M. C, HARRIS, A. L, HARTLEY, J. A, MASTERS, J. R. W, HICKSON, I. D

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MDM2 Mediated Nuclear Exclusion of p53 Attenuates Etoposide-Induced Apoptosis in Neuroblastoma Cells by Rodriguez-Lopez, Ana M., Xenaki, Dia, Eden, Tim O. B., Hickman, John A., Chresta, Christine M.

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Apoptosis: its relevance to carcinogenesis and anti-tumour drug sensitivity by Chresta, C M, Hickman, J A

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Depletion of cellular glutathione by N',N'-bis(trans-4-hydroxycyclohexyl)-N'-nitrosourea as a determinant of sensitivity of K562 human leukemia cells to 4-hydroperoxycyclophosphami... by CHRESTA, C. M, CROOK, T. R, SOUHAMI, R. L

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Potentiation of etoposide-induced cytotoxicity and DNA damage in CCRF-CEM cells by pretreatment with non-cytotoxic concentrations of arabinosyl cytosine by CHRESTA, C. M, HICKS, R, HARTLEY, J. A, SOUHAMI, R. L

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Depletion of cellular glutathione by N,N'-Bis(trans-4-hydroxycyclohexyl)-N'-nitrosourea as a determinant of sensitivity of K562 human leukemia cells to 4-hydroperoxycyclo-phosphami... by Chresta, C M, Crook, T R, Souhami, R L

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AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules by Guichard, Sylvie M, Curwen, Jon, Bihani, Teeru, D'Cruz, Celina M, Yates, James W T, Grondine, Michael, Howard, Zoe, Davies, Barry R, Bigley, Graham, Klinowska, Teresa, Pike, Kurt G, Pass, Martin, Chresta, Christine M, Polanska, Urszula M, McEwen, Robert, Delpuech, Oona, Green, Stephen, Cosulich, Sabina C

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AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity by CHRESTA, Christine M, DAVIES, Barry R, JAMES, Dominic, HOWARD, Zoe, DUDLEY, Phillippa, HUGHES, Gareth, SMITH, Lisa, MAGUIRE, Sharon, HUMMERSONE, Marc, MALAGU, Karine, MENEAR, Keith, JENKINS, Richard, HICKSON, Ian, JACOBSEN, Matt, SMITH, Graeme C. M, GUICHARD, Sylvie, PASS, Martin, HARDING, Tom, COSULICH, Sabina, CRITCHLOW, Susan E, VINCENT, John P, ELLSTON, Rebecca, JONES, Darren, SINI, Patrizia

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Design and campaign synthesis of pyridine-based histone deacetylase inhibitors by Andrews, David M., Gibson, Keith M., Graham, Mark A., Matusiak, Zbigniew S., Roberts, Craig A., Stokes, Elaine S.E., Brady, Madeleine C., Chresta, Christine M.

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Design and campaign synthesis of piperidine- and thiazole-based histone deacetylase inhibitors by Andrews, David M., Stokes, Elaine S.E., Carr, Greg R., Matusiak, Zbigniew S., Roberts, Craig A., Waring, Michael J., Brady, Madeleine C., Chresta, Christine M., East, Simon J.

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