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Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: Metabolism-directed optimization studies towards orally bioavailable derivati...
by
Vergne, Fabrice
,
Bernardelli, Patrick
,
Lorthiois, Edwige
,
Pham, Nga
,
Proust, Emmanuelle
,
Oliveira, Chrystelle
,
Mafroud, Abdel-Kader
,
Ducrot, Pierre
,
Wrigglesworth, Roger
,
Berlioz-Seux, Françoise
,
Coleon, Francis
,
Chevalier, Eric
,
Moreau, François
,
Idrissi, Moulay
,
Tertre, Anita
,
Descours, Arnaud
,
Berna, Patrick
,
Li, Mei
Published in
Bioorganic & medicinal chemistry letters
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Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques
by
Marlin, Romain
,
Godot, Veronique
,
Cardinaud, Sylvain
,
Galhaut, Mathilde
,
Coleon, Severin
,
Zurawski, Sandra
,
Dereuddre-Bosquet, Nathalie
,
Cavarelli, Mariangela
,
Gallouët, Anne-Sophie
,
Maisonnasse, Pauline
,
Dupaty, Léa
,
Fenwick, Craig
,
Naninck, Thibaut
,
Lemaitre, Julien
,
Gomez-Pacheco, Mario
,
Kahlaoui, Nidhal
,
Contreras, Vanessa
,
Relouzat, Francis
,
Fang, Raphaël Ho Tsong
,
Wang, Zhiqing
,
Ellis, Jerome
,
Chapon, Catherine
,
Centlivre, Mireille
,
Wiedemann, Aurelie
,
Lacabaratz, Christine
,
Surenaud, Mathieu
,
Szurgot, Inga
,
Liljeström, Peter
,
Planas, Delphine
,
Bruel, Timothée
,
Schwartz, Olivier
,
Werf, Sylvie van der
,
Pantaleo, Giuseppe
,
Prague, Mélanie
,
Thiébaut, Rodolphe
,
Zurawski, Gerard
,
Lévy, Yves
,
Grand, Roger Le
Published in
Nature communications
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3',5'-Cyclic-Amp Phosphodiesterases - Antagonists & Inhibitors
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3',5'-Cyclic-Amp Phosphodiesterases - Metabolism
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631/250/590/2294
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