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Abstract B177: The discovery and preclinical characterization of AMG 193, a first-in-class MTA-cooperative PRMT5 inhibitor with broad activity against MTAP -null cancers
by
Belmontes, Brian
,
Slemmons, Katherine
,
Liu, Siyuan
,
Policheni, Antonia
,
Moriguchi, Jodi
,
Tan, Hong
,
Xie, Fang
,
Aeffner, Famke
,
Rees, Matthew G
,
Ronan, Melissa M
,
Roth, Jennifer A
,
Vestergaard, Mikkel
,
Cowland, Sanne
,
Andersson, Jan
,
Sarvary, Ian
,
Lopez, Patricia
,
Tamayo, Nuria
,
Pettus, Liping H
,
Mukund, Susmith
,
Allen, Jennifer R
,
Glad, Sanne
,
Bourbeau, Matthew P
Published in
Molecular cancer therapeutics
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Abstract 1807: The discovery and preclinical characterization of the MTA cooperative PRMT5 inhibitor AM-9747
by
Belmontes, Brian
,
Policheni, Antonia
,
Liu, Siyuan
,
Slemmons, Katherine
,
Moriguchi, Jodi
,
Ma, Hayley
,
Aiello, Daniel
,
Yang, Yajing
,
Vestergaard, Mikkel
,
Cowland, Sanne
,
Anderson, Jan
,
Sarvary, Ian
,
Tamayo, Nuria
,
Pettus, Liping
,
Mukund, Susmith
,
Pope, Leszek
,
Allen, Jennifer R.
,
Glad, Sanne
,
Bourbeau, Matthew
,
Hughes, Paul E.
Published in
Cancer research (Chicago, Ill.)
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