1367 A rational approach to selecting CD3-binding antibodies for T-cell engager development by Mai, Juntao (Matt), Puyraimond, Valentine de, Pouliot, Philippe, Caldwell, Kate, Clifford, Lauren, Goodman, Allison, Farber, Patrick, Rowe, Patrick, Dhupar, Harveer, Reimer, Janice, Herve, Karine, Li, Vivian, Yu, Irene, Marwick, John, Blamey, Nathalie, Cid, Melissa, Crichlow, Cindy-Lee, Bolten, Lena M, Pinsky, Tova, Volkers, Gesa, Bodhankar, Girija, Jong, Caitlyn De, Cullen, Sophie, Xiang, Ping, Lee, Ahn, Conaghan, Gabrielle, Samiotakis, Antonios, Hannie, Stefan, Chappell, Rhys, Lathouwers, Emma, Chong, Lauren, Gibson, Kate, Masterman, Stephanie K, Brown, Kirstin, Fogg, Mark, Tonikian, Raffi, Jacobs, Tim, Yamniuk, Aaron, Barnhart, Bryan C

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Emerging Priorities for Microbiome Research by Cullen, Chad M, Aneja, Kawalpreet K, Beyhan, Sinem, Cho, Clara E, Woloszynek, Stephen, Convertino, Matteo, McCoy, Sophie J, Zhang, Yanyan, Anderson, Matthew Z, Alvarez-Ponce, David, Smirnova, Ekaterina, Karstens, Lisa, Dorrestein, Pieter C, Li, Hongzhe, Sen Gupta, Ananya, Cheung, Kevin, Powers, Jennifer Gloeckner, Zhao, Zhengqiao, Rosen, Gail L

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A massive quiescent galaxy at redshift 4.658 by Carnall, Adam C., McLure, Ross J., Dunlop, James S., McLeod, Derek J., Wild, Vivienne, Cullen, Fergus, Magee, Dan, Begley, Ryan, Cimatti, Andrea, Donnan, Callum T., Hamadouche, Massissilia L., Jewell, Sophie M., Walker, Sam

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Bioenergetics and synaptic plasticity as potential targets for individualizing treatment for depression by Price, J. Blair, Bronars, Carrie, Erhardt, Sophie, Cullen, Kathyrn R., Schwieler, Lilly, Berk, Michael, Walder, Ken, McGee, Sean L., Frye, Mark A., Tye, Susannah J.

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Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice by Tang, Xin, Drotar, Jesse, Li, Keji, Clairmont, Cullen D, Brumm, Anna Sophie, Sullins, Austin J, Wu, Hao, Liu, Xiaoxiao Shawn, Wang, Jinhua, Gray, Nathanael S, Sur, Mriganka, Jaenisch, Rudolf

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Planet-compatible pathways for transitioning the chemical industry by Meng, Fanran, Wagner, Andreas, Kremer, Alexandre B, Kanazawa, Daisuke, Leung, Jane J, Goult, Peter, Guan, Min, Herrmann, Sophie, Speelman, Eveline, Sauter, Pim, Lingeswaran, Shajeeshan, Stuchtey, Martin M, Hansen, Katja, Masanet, Eric, Serrenho, André C, Ishii, Naoko, Kikuchi, Yasunori, Cullen, Jonathan M

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Obesity and leptin in breast cancer angiogenesis by Lagarde, Courtney B, Thapa, Kapil, Cullen, Nicole M, Hawes, Mackenzie L, Salim, Khudeja, Benz, Megan C, Dietrich, Sophie R, Burow, Brandon E, Bunnell, Bruce A, Martin, Elizabeth C, Collins-Burow, Bridgette M, Lynch, Ronald M, Hoang, Van T, Burow, Matthew E, Fang, Jennifer S

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Attribution of the record high Central England temperature of 2014 to anthropogenic influences by King, Andrew D, Jan van Oldenborgh, Geert, Karoly, David J, Lewis, Sophie C, Cullen, Heidi

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Acceptability and use of coercive methods across differing service configurations with and without seclusion and/or psychiatric intensive care units by Pettit, Sophie A., Bowers, Len, Tulloch, Alex, Cullen, Alexis E., Moylan, Lois Biggin, Sethi, Faisil, McCrone, Paul, Baker, John, Quirk, Alan, Stewart, Duncan

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Reduced Serological Response to COVID-19 Booster Vaccine is Associated with Reduced B Cell Memory in Patients With Inflammatory Bowel Disease; VARIATION [VAriability in Response in... by Doherty, Jayne, O’Morain, Neil, Stack, Roisin, Tosetto, Miriam, Inzitiari, Rosanna, O’Reilly, Sophie, Gu, Lili, Sheridan, Juliette, Cullen, Garret, Mc Dermott, Edel, Buckley, Maire, Horgan, Gareth, Mulcahy, Hugh, Walshe, Margaret, Ryan, Elizabeth J, Gautier, Virginie, Prostko, John, Frias, Edwin, Daghfal, David, Doran, Peter, O’Morain, Colm, Doherty, Glen A

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The Developing Human Connectome Project Neonatal Data Release by Edwards, A David, Rueckert, Daniel, Smith, Stephen M, Abo Seada, Samy, Alansary, Amir, Almalbis, Jennifer, Allsop, Joanna, Andersson, Jesper, Arichi, Tomoki, Arulkumaran, Sophie, Bastiani, Matteo, Batalle, Dafnis, Baxter, Luke, Bozek, Jelena, Braithwaite, Eleanor, Brandon, Jacqueline, Carney, Olivia, Chew, Andrew, Christiaens, Daan, Chung, Raymond, Colford, Kathleen, Cordero-Grande, Lucilio, Counsell, Serena J, Cullen, Harriet, Cupitt, John, Curtis, Charles, Davidson, Alice, Deprez, Maria, Dillon, Louise, Dimitrakopoulou, Konstantina, Dimitrova, Ralica, Duff, Eugene, Falconer, Shona, Farahibozorg, Seyedeh-Rezvan, Fitzgibbon, Sean P, Gao, Jianliang, Gaspar, Andreia, Harper, Nicholas, Harrison, Sam J, Hughes, Emer J, Hutter, Jana, Jenkinson, Mark, Jbabdi, Saad, Jones, Emily, Karolis, Vyacheslav, Kyriakopoulou, Vanessa, Lenz, Gregor, Makropoulos, Antonios, Malik, Shaihan, Mason, Luke, Mortari, Filippo, Nosarti, Chiara, Nunes, Rita G, O'Keeffe, Camilla, O'Muircheartaigh, Jonathan, Patel, Hamel, Passerat-Palmbach, Jonathan, Pietsch, Maximillian, Price, Anthony N, Robinson, Emma C, Rutherford, Mary A, Schuh, Andreas, Sotiropoulos, Stamatios, Steinweg, Johannes, Teixeira, Rui Pedro Azeredo Gomes, Tenev, Tencho, Tournier, Jacques-Donald, Tusor, Nora, Uus, Alena, Vecchiato, Katy, Williams, Logan Z J, Wright, Robert, Wurie, Julia, Hajnal, Joseph V

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The Copernicus Sentinel-6 mission: Enhanced continuity of satellite sea level measurements from space by Donlon, Craig J., Cullen, Robert, Giulicchi, Luisella, Vuilleumier, Pierrik, Francis, C. Richard, Kuschnerus, Mieke, Simpson, William, Bouridah, Abderrazak, Caleno, Mauro, Bertoni, Roberta, Rancaño, Jesus, Pourier, Eric, Hyslop, Andrew, Mulcahy, James, Knockaert, Robert, Hunter, Christopher, Webb, Alan, Fornari, Marco, Vaze, Parag, Brown, Shannon, Willis, Joshua, Desai, Shailen, Desjonqueres, Jean-Damien, Scharroo, Remko, Martin-Puig, Cristina, Leuliette, Eric, Egido, Alejandro, Smith, Walter H.F., Bonnefond, Pascal, Le Gac, Sophie, Picot, Nicolas, Tavernier, Gilles

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Reduced GABAergic Neuron Excitability, Altered Synaptic Connectivity, and Seizures in a KCNT1 Gain-of-Function Mouse Model of Childhood Epilepsy by Shore, Amy N., Colombo, Sophie, Tobin, William F., Petri, Sabrina, Cullen, Erin R., Dominguez, Soledad, Bostick, Christopher D., Beaumont, Michael A., Williams, Damian, Khodagholy, Dion, Yang, Mu, Lutz, Cathleen M., Peng, Yueqing, Gelinas, Jennifer N., Goldstein, David B., Boland, Michael J., Frankel, Wayne N., Weston, Matthew C.

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Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression by Tye, Susannah, Price, Joshua, Walker, Adam, Sutor, Shari, Erhardt, Sophie, Schwieler, Lilly, Cullen, Kathryn, Voort, Jennifer Vande, Frye, Mark, Bobo, William, Shiroma, Paulo

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Reassessing long-standing meteorological records: an example using the national hottest day in Ireland by Dooley, Katherine, Kelly, Ciaran, Seifert, Natascha, Myslinski, Therese, O'Kelly, Sophie, Siraj, Rushna, Crosby, Ciara, Dunne, Jack Kevin, McCauley, Kate, Donoghue, James, Gaddren, Eoin, Conway, Daniel, Cooney, Jordan, McCarthy, Niamh, Cullen, Eoin, Noone, Simon, Murphy, Conor, Thorne, Peter

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Neurocognitive performance in children aged 9–12 years who present putative antecedents of schizophrenia by Cullen, Alexis E, Dickson, Hannah, West, Sophie A, Morris, Robin G, Mould, Glenn L, Hodgins, Sheilagh, Murray, Robin M, Laurens, Kristin R

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Concurrent Validity and Reliability of Suicide Risk Assessment Instruments: A Meta-Analysis of 20 Instruments Across 27 International Cohorts by Campos, Adrian I., Van Velzen, Laura S., Veltman, Dick J., Pozzi, Elena, Ambrogi, Sonia, Ballard, Elizabeth D., Banaj, Nerisa, Başgöze, Zeynep, Bellow, Sophie, Benedetti, Francesco, Bollettini, Irene, Brosch, Katharina, Canales-Rodríguez, Erick J., Clarke-Rubright, Emily K., Colic, Lejla, Connolly, Colm G., Courtet, Philippe, Cullen, Kathryn R., Dannlowski, Udo, Dauvermann, Maria R., Davey, Christopher G., Deverdun, Jeremy, Dohm, Katharina, Erwin-Grabner, Tracy, Goya-Maldonado, Roberto, Fani, Negar, Fortea, Lydia, Fuentes-Claramonte, Paola, Gonul, Ali Saffet, Gotlib, Ian H., Grotegerd, Dominik, Harris, Mathew A., Harrison, Ben J., Haswell, Courtney C., Hawkins, Emma L., Hill, Dawson, Hirano, Yoshiyuki, Ho, Tiffany C., Jollant, Fabrice, Jovanovic, Tanja, Kircher, Tilo, Klimes-Dougan, Bonnie, le Bars, Emmanuelle, Lochner, Christine, McIntosh, Andrew M., Meinert, Susanne, Mekawi, Yara, Melloni, Elisa, Mitchell, Philip, Morey, Rajendra A., Nakagawa, Akiko, Nenadić, Igor, Olié, Emilie, Pereira, Fabricio, Phillips, Rachel D., Piras, Fabrizio, Poletti, Sara, Pomarol-Clotet, Edith, Radua, Joaquim, Ressler, Kerry J., Roberts, Gloria, Rodriguez-Cano, Elena, Sacchet, Matthew D., Salvador, Raymond, Sandu, Anca-Larisa, Shimizu, Eiji, Singh, Aditya, Spalletta, Gianfranco, Steele, J. Douglas, Stein, Dan J., Stein, Frederike, Stevens, Jennifer S., Teresi, Giana I., Uyar-Demir, Aslihan, van der Wee, Nic J., van der Werff, Steven J., van Rooij, Sanne J. H., Vecchio, Daniela, Verdolini, Norma, Vieta, Eduard, Waiter, Gordon D., Whalley, Heather, Whittle, Sarah L., Yang, Tony T., Zarate, Carlos A., Thompson, Paul M., Jahanshad, Neda, van Harmelen, Anne-Laura, Blumberg, Hilary P., Schmaal, Lianne, Rentería, Miguel E.

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Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination by Tea, Fiona, Lopez, Joseph A, Ramanathan, Sudarshini, Merheb, Vera, Lee, Fiona X Z, Zou, Alicia, Pilli, Deepti, Patrick, Ellis, van der Walt, Anneke, Monif, Mastura, Tantsis, Esther M, Yiu, Eppie M, Vucic, Steve, Henderson, Andrew P D, Fok, Anthony, Fraser, Clare L, Lechner-Scott, Jeanette, Reddel, Stephen W, Broadley, Simon, Barnett, Michael H, Brown, David A, Lunemann, Jan D, Dale, Russell C, Brilot, Fabienne

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Biophysical and Immunological Characterization and In Vivo Pharmacokinetics and Toxicology in Nonhuman Primates of the Anti-PD-1 Antibody Pembrolizumab by Hutchins, Beth, Starling, Gary C, McCoy, Mark A, Herzyk, Danuta, Poulet, Frederique M, Dulos, John, Liu, Liming, Kang, Soonmo Peter, Fayadat-Dilman, Laurence, Hsieh, Mark, Andrews, Christine L, Ayanoglu, Gulesi, Cullen, Constance, Malefyt, Rene de Waal, Kastelein, Robert A, Saux, Sabine Le, Lee, Julie, Li, Sophie, Malashock, Dan, Sadekova, Svetlana, Soder, George, van Eenennaam, Hans, Willingham, Aarron, Yu, Ying, Streuli, Michel, Carven, Gregory J, van Elsas, Andrea

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Individual Factors Including Age, BMI, and Heritable Factors Underlie Temperature Variation in Sickness and in Health: An Observational, Multi-cohort Study by Penfold, Rose S, Zazzara, Maria Beatrice, Österdahl, Marc F, Welch, Carly, Ni Lochlainn, Mary, Freidin, Maxim B, Bowyer, Ruth C E, Thompson, Ellen, Antonelli, Michela, Tan, Yu Xian Rachel, Sudre, Carole H, Modat, Marc, Murray, Benjamin, Wolf, Jonathan, Ourselin, Sebastien, Veenith, Tonny, Lord, Janet M, Steves, Claire J

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