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Cytochrome P450 reductase dependent inhibition of cytochrome P450 2B1 activity: Implications for gene directed enzyme prodrug therapy
by
Lengler, Johannes
,
Omann, Markus
,
Düvier, Dana
,
Holzmüller, Harry
,
Gregor, Wolfgang
,
Salmons, Brian
,
Günzburg, Walter H.
,
Renner, Matthias
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Biochemical pharmacology
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Biochemical Pharmacology
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Animals
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Antineoplastic Agents, Alkylating - Metabolism
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Antineoplastic Agents, Alkylating - Pharmacology
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Biological And Medical Sciences
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Blotting, Western
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Cell Line
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Cell Line, Tumor
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Cell Survival - Drug Effects
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Cyp2B1
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Cytochrome C Group - Metabolism
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Cytochrome P-450 Cyp2B1 - Genetics
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Cytochrome P-450 Cyp2B1 - Metabolism
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Cytochrome P450
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Cytochrome P450 Reductase
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Dose-Response Relationship, Drug
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Genetic Therapy - Methods
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Humans
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Ifosfamide
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