Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes by Chen, Rui, Mias, George I., Li-Pook-Than, Jennifer, Jiang, Lihua, Lam, Hugo Y.K., Chen, Rong, Miriami, Elana, Karczewski, Konrad J., Hariharan, Manoj, Dewey, Frederick E., Cheng, Yong, Clark, Michael J., Im, Hogune, Habegger, Lukas, Balasubramanian, Suganthi, O'Huallachain, Maeve, Dudley, Joel T., Hillenmeyer, Sara, Haraksingh, Rajini, Sharon, Donald, Euskirchen, Ghia, Lacroute, Phil, Bettinger, Keith, Boyle, Alan P., Kasowski, Maya, Grubert, Fabian, Seki, Scott, Garcia, Marco, Whirl-Carrillo, Michelle, Gallardo, Mercedes, Blasco, Maria A., Greenberg, Peter L., Snyder, Phyllis, Klein, Teri E., Altman, Russ B., Butte, Atul J., Ashley, Euan A., Gerstein, Mark, Nadeau, Kari C., Tang, Hua, Snyder, Michael

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Clinical Interpretation and Implications of Whole-Genome Sequencing by Dewey, Frederick E, Grove, Megan E, Pan, Cuiping, Goldstein, Benjamin A, Bernstein, Jonathan A, Chaib, Hassan, Merker, Jason D, Goldfeder, Rachel L, Enns, Gregory M, David, Sean P, Pakdaman, Neda, Ormond, Kelly E, Caleshu, Colleen, Kingham, Kerry, Klein, Teri E, Whirl-Carrillo, Michelle, Sakamoto, Kenneth, Wheeler, Matthew T, Butte, Atul J, Ford, James M, Boxer, Linda, Ioannidis, John P. A, Yeung, Alan C, Altman, Russ B, Assimes, Themistocles L, Snyder, Michael, Ashley, Euan A, Quertermous, Thomas

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Performance comparison of whole-genome sequencing platforms by Lam, Hugo Y K, Clark, Michael J, Chen, Rui, Chen, Rong, Natsoulis, Georges, O'Huallachain, Maeve, Dewey, Frederick E, Habegger, Lukas, Ashley, Euan A, Gerstein, Mark B, Butte, Atul J, Ji, Hanlee P, Snyder, Michael

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Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease by Zhu, Na, Welch, Carrie L, Wang, Jiayao, Allen, Philip M, Gonzaga-Jauregui, Claudia, Ma, Lijiang, King, Alejandra K, Krishnan, Usha, Rosenzweig, Erika B, Ivy, D Dunbar, Austin, Eric D, Hamid, Rizwan, Pauciulo, Michael W, Lutz, Katie A, Nichols, William C, Reid, Jeffrey G, Overton, John D, Baras, Aris, Dewey, Frederick E, Shen, Yufeng, Chung, Wendy K

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Electrocardiographic predictors of atrial fibrillation by Perez, Marco V., MD, Dewey, Frederick E., MD, Marcus, Rachel, MD, Ashley, Euan A., MRCP, DPhil, MD, Al-Ahmad, Amin A., MD, Wang, Paul J., MD, Froelicher, Victor F., MD, FACC

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Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure by Perez, Marco V., MD, Pavlovic, Aleksandra, BS, Shang, Ching, PhD, Wheeler, Matthew T., MD, PhD, Miller, Clint L., PhD, Liu, Jing, MD, Dewey, Frederick E., MD, PhD, Pan, Stephen, MD, MS, Thanaporn, Porama K., MD, Absher, Devin, PhD, Brandimarto, Jeffrey, PhD, Salisbury, Heidi, RN, MSN, CNS, Chan, Khin, MD, Mukherjee, Rupak, PhD, Konadhode, Roda P., PhD, Myers, Richard M., PhD, Sedehi, Daniel, MD, Scammell, Thomas E., MD, Quertermous, Thomas, MD, Cappola, Thomas, MD, ScM, Ashley, Euan A., MRCP, DPhil

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Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data by Dewey, Frederick E, Grove, Megan E, Priest, James R, Waggott, Daryl, Batra, Prag, Miller, Clint L, Wheeler, Matthew, Zia, Amin, Pan, Cuiping, Karzcewski, Konrad J, Miyake, Christina, Whirl-Carrillo, Michelle, Klein, Teri E, Datta, Somalee, Altman, Russ B, Snyder, Michael, Quertermous, Thomas, Ashley, Euan A

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Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR Study by Dewey, Frederick E.

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Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation by Choi, Seung Hoan, Weng, Lu-Chen, Roselli, Carolina, Lin, Honghuang, Haggerty, Christopher M, Shoemaker, M. Benjamin, Barnard, John, Arking, Dan E, Chasman, Daniel I, Albert, Christine M, Chaffin, Mark, Tucker, Nathan R, Smith, Jonathan D, Gupta, Namrata, Gabriel, Stacey, Margolin, Lauren, Shea, Marisa A, Shaffer, Christian M, Yoneda, Zachary T, Boerwinkle, Eric, Smith, Nicholas L, Silverman, Edwin K, Redline, Susan, Vasan, Ramachandran S, Burchard, Esteban G, Gogarten, Stephanie M, Laurie, Cecelia, Blackwell, Thomas W, Abecasis, Gonçalo, Carey, David J, Fornwalt, Brandon K, Smelser, Diane T, Baras, Aris, Dewey, Frederick E, Jaquish, Cashell E, Papanicolaou, George J, Sotoodehnia, Nona, Van Wagoner, David R, Psaty, Bruce M, Kathiresan, Sekar, Darbar, Dawood, Alonso, Alvaro, Heckbert, Susan R, Chung, Mina K, Roden, Dan M, Benjamin, Emelia J, Murray, Michael F, Lunetta, Kathryn L, Lubitz, Steven A, Ellinor, Patrick T

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Genetic identification of familial hypercholesterolemia within a single U.S. health care system by Abul-Husn, Noura S., Manickam, Kandamurugu, Jones, Laney K., Wright, Eric A., Hartzel, Dustin N., Gonzaga-Jauregui, Claudia, O'Dushlaine, Colm, Leader, Joseph B., Kirchner, H. Lester, Lindbuchler, D'Andra M., Barr, Marci L., Giovanni, Monica A., Ritchie, Marylyn D., Overton, John D., Reid, Jeffrey G., Metpally, Raghu P. R., Wardeh, Amr H., Borecki, Ingrid B., Yancopoulos, George D., Baras, Aris, Shuldiner, Alan R., Gottesman, Omri, Ledbetter, David H., Carey, David J., Dewey, Frederick E., Murray, Michael F.

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Prognostic value of heart rate increase at onset of exercise testing by LEEPER, Nicholas J, DEWEY, Frederick E, ASHLEY, Euan A, SANDRI, Marcus, SWEE YAW TAN, HADLEY, David, MYERS, Jonathan, FROELICHER, Victor

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MAPPIN: a method for annotating, predicting pathogenicity and mode of inheritance for nonsynonymous variants by Gosalia, Nehal, Economides, Aris N, Dewey, Frederick E, Balasubramanian, Suganthi

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Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease by Khera, Amit V, Won, Hong-Hee, Peloso, Gina M, O’Dushlaine, Colm, Liu, Dajiang, Stitziel, Nathan O, Natarajan, Pradeep, Nomura, Akihiro, Emdin, Connor A, Gupta, Namrata, Borecki, Ingrid B, Asselta, Rosanna, Duga, Stefano, Merlini, Piera Angelica, Correa, Adolfo, Kessler, Thorsten, Wilson, James G, Bown, Matthew J, Hall, Alistair S, Braund, Peter S, Carey, David J, Murray, Michael F, Kirchner, H. Lester, Leader, Joseph B, Lavage, Daniel R, Manus, J. Neil, Hartzel, Dustin N, Samani, Nilesh J, Schunkert, Heribert, Marrugat, Jaume, Elosua, Roberto, McPherson, Ruth, Farrall, Martin, Watkins, Hugh, Lander, Eric S, Rader, Daniel J, Danesh, John, Ardissino, Diego, Gabriel, Stacey, Willer, Cristen, Abecasis, Gonçalo R, Saleheen, Danish, Dewey, Frederick E, Kathiresan, Sekar

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Genomics-First Evaluation of Heart Disease Associated With Titin-Truncating Variants by Haggerty, Christopher M, Damrauer, Scott M, Levin, Michael G, Birtwell, David, Carey, David J, Golden, Alicia M, Hartzel, Dustin N, Hu, Yirui, Judy, Renae, Kelly, Melissa A, Kember, Rachel L, Lester Kirchner, H, Leader, Joseph B, Liang, Lusha, McDermott-Roe, Chris, Babu, Apoorva, Morley, Michael, Nealy, Zachariah, Person, Thomas N, Pulenthiran, Arichanah, Small, Aeron, Smelser, Diane T, Stahl, Richard C, Sturm, Amy C, Williams, Heather, Baras, Aris, Margulies, Kenneth B, Cappola, Thomas P, Dewey, Frederick E, Verma, Anurag, Zhang, Xinyuang, Correa, Adolfo, Hall, Michael E, Wilson, James G, Ritchie, Marylyn D, Rader, Daniel J, Murray, Michael F, Fornwalt, Brandon K, Arany, Zoltan

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Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes by Gusarova, Viktoria, O’Dushlaine, Colm, Teslovich, Tanya M., Benotti, Peter N., Mirshahi, Tooraj, Gottesman, Omri, Van Hout, Cristopher V., Murray, Michael F., Mahajan, Anubha, Nielsen, Jonas B., Fritsche, Lars, Wulff, Anders Berg, Gudbjartsson, Daniel F., Sjögren, Marketa, Emdin, Connor A., Scott, Robert A., Lee, Wen-Jane, Small, Aeron, Kwee, Lydia C., Dwivedi, Om Prakash, Prasad, Rashmi B., Bruse, Shannon, Lopez, Alexander E., Penn, John, Marcketta, Anthony, Leader, Joseph B., Still, Christopher D., Kirchner, H. Lester, Mirshahi, Uyenlinh L., Wardeh, Amr H., Hartle, Cassandra M., Habegger, Lukas, Fetterolf, Samantha N., Tusie-Luna, Teresa, Morris, Andrew P., Holm, Hilma, Steinthorsdottir, Valgerdur, Sulem, Patrick, Thorsteinsdottir, Unnur, Rotter, Jerome I., Chuang, Lee-Ming, Damrauer, Scott, Birtwell, David, Brummett, Chad M., Khera, Amit V., Natarajan, Pradeep, Orho-Melander, Marju, Flannick, Jason, Lotta, Luca A., Willer, Cristen J., Holmen, Oddgeir L., Ritchie, Marylyn D., Ledbetter, David H., Murphy, Andrew J., Borecki, Ingrid B., Reid, Jeffrey G., Overton, John D., Hansson, Ola, Groop, Leif, Shah, Svati H., Kraus, William E., Rader, Daniel J., Chen, Yii-Der I., Hveem, Kristian, Wareham, Nicholas J., Kathiresan, Sekar, Melander, Olle, Stefansson, Kari, Nordestgaard, Børge G., Tybjærg-Hansen, Anne, Abecasis, Goncalo R., Altshuler, David, Florez, Jose C., Boehnke, Michael, McCarthy, Mark I., Yancopoulos, George D., Carey, David J., Shuldiner, Alan R., Baras, Aris, Dewey, Frederick E., Gromada, Jesper

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Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation by Homburger, Julian R., Green, Eric M., Caleshu, Colleen, Sunitha, Margaret S., Taylor, Rebecca E., Ruppel, Kathleen M., Metpally, Raghu Prasad Rao, Colan, Steven D., Michels, Michelle, Day, Sharlene M., Olivotto, Iacopo, Bustamante, Carlos D., Dewey, Frederick E., Ho, Carolyn Y., Spudich, James A., Ashley, Euan A.

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Does Size Matter? : Clinical Applications of Scaling Cardiac Size and Function for Body Size by DEWEY, Frederick E, ROSENTHAL, David, MURPHY, Daniel J, FROELICHER, Victor F, ASHLEY, Euan A

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Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development by Nielsen, Jonas B., Fritsche, Lars G., Zhou, Wei, Teslovich, Tanya M., Holmen, Oddgeir L., Gustafsson, Stefan, Gabrielsen, Maiken E., Schmidt, Ellen M., Beaumont, Robin, Wolford, Brooke N., Lin, Maoxuan, Brummett, Chad M., Preuss, Michael H., Refsgaard, Lena, Bottinger, Erwin P., Graham, Sarah E., Surakka, Ida, Chu, Yunhan, Skogholt, Anne Heidi, Dalen, Håvard, Boyle, Alan P., Oral, Hakan, Herron, Todd J., Kitzman, Jacob, Jalife, José, Svendsen, Jesper H., Olesen, Morten S., Njølstad, Inger, Løchen, Maja-Lisa, Baras, Aris, Gottesman, Omri, Marcketta, Anthony, O’Dushlaine, Colm, Ritchie, Marylyn D., Wilsgaard, Tom, Loos, Ruth J.F., Frayling, Timothy M., Boehnke, Michael, Ingelsson, Erik, Carey, David J., Dewey, Frederick E., Kang, Hyun M., Abecasis, Gonçalo R., Hveem, Kristian, Willer, Cristen J.

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Clinical assessment incorporating a personal genome by Ashley, Euan A, Dr, Butte, Atul J, MD, Wheeler, Matthew T, MD, Chen, Rong, PhD, Klein, Teri E, PhD, Dewey, Frederick E, MD, Dudley, Joel T, Ormond, Kelly E, MSc, Pavlovic, Aleksandra, BS, Morgan, Alexander A, MS, Pushkarev, Dmitry, Neff, Norma F, PhD, Hudgins, Louanne, Prof, Gong, Li, PhD, Hodges, Laura M, PhD, Berlin, Dorit S, PhD, Thorn, Caroline F, PhD, Sangkuhl, Katrin, PhD, Hebert, Joan M, MA, Woon, Mark, BSE, Sagreiya, Hersh, Whaley, Ryan, BS, Knowles, Joshua W, MD, Chou, Michael F, PhD, Thakuria, Joseph V, MD, Rosenbaum, Abraham M, PhD, Zaranek, Alexander Wait, PhD, Church, George M, PhD, Greely, Henry T, Prof, Quake, Stephen R, PhD, Altman, Russ B, Prof

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CLAMMS: a scalable algorithm for calling common and rare copy number variants from exome sequencing data by Packer, Jonathan S, Maxwell, Evan K, O'Dushlaine, Colm, Lopez, Alexander E, Dewey, Frederick E, Chernomorsky, Rostislav, Baras, Aris, Overton, John D, Habegger, Lukas, Reid, Jeffrey G

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