451 Two Insulin Receptor Isoforms Confer Intrinsic Resistance to the Antibody Against Insulin-like Growth Factor Receptor I by Forest, A, Amatulli, M, Damoci, C, Ludwig, D, Baltes, N, Fiebig, H, Houghton, P, Smith, M, Benjamin, L, Novosyadlyy, R

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Development of a Fully Human Anti-PDGFRβ Antibody That Suppresses Growth of Human Tumor Xenografts and Enhances Antitumor Activity of an Anti-VEGFR2 Antibody by Shen, Juqun, Vil, Marie Danielle, Prewett, Marie, Damoci, Chris, Zhang, Haifan, Li, Huiling, Jimenez, Xenia, Deevi, Dhanvanthri S., Iacolina, Michelle, Kayas, Anthony, Bassi, Rajiv, Persaud, Kris, Rohoza-Asandi, Anna, Balderes, Paul, Loizos, Nick, Ludwig, Dale L., Tonra, James, Witte, Larry, Zhu, Zhenping

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55 POSTER Combination therapy of an anti-PDGFRb antibody with an anti-VEGFR2 antibody leads to enhanced antitumor activity by Shen, J, Prewett, M, Damoci, C, Zhang, H, Vil, M.D, Li, H, Tonra, J, Zhu, Z

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An antibody directed against PDGF receptor β enhances the antitumor and the anti-angiogenic activities of an anti-VEGF receptor 2 antibody by Shen, Juqun, Vil, Marie D., Zhang, Haifan, Tonra, James R., Rong, Ling L., Damoci, Chris, Prewett, Marie, Deevi, Dhanvanthri S., Kearney, Jessica, Surguladze, David, Jimenez, Xenia, Iacolina, Michelle, Bassi, Rajiv, Zhou, Kai, Balderes, Paul, Mangalampalli, Venkat R.M., Loizos, Nick, Ludwig, Dale L., Zhu, Zhenping

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299 Preclinical in vivo evaluation of a doxorubicin-antibody conjugate for treating multiple myeloma by Griffiths, G.L., Sapra, P., Pickett, J., Cardillo, T., Stein, R., Govindan, S.V., Sheerin, A., Damoci, C., Horak, I.D., Goldenberg, D.M.

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290 Pharmacokinetics and tissue biodistribution of a doxorubicin-antibody conjugate in mice by Sapra, P., Griffiths, G., Govindan, S., Damoci, C., Pickett, J., Sheerin, A., Cardillo, T., Hansen, H., Horak, I., Goldenberg, D.

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Rationally repurposed nitroxoline inhibits preclinical models of Epstein–Barr virus-associated lymphoproliferation by Ibáñez de Garayo, Maite, Liu, Wendi, Rondeau, Nicole C., Damoci, Christopher B., Miranda, JJ L.

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Intrinsic Resistance to Cixutumumab Is Conferred by Distinct Isoforms of the Insulin Receptor by Forest, Amelie, Amatulli, Michael, Ludwig, Dale L, Damoci, Christopher B, Wang, Ying, Burns, Colleen A, Donoho, Gregory P, Zanella, Nina, Fiebig, Heinz H, Prewett, Marie C, Surguladze, David, DeLigio, James T, Houghton, Peter J, Smith, Malcolm A, Novosiadly, Ruslan

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A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth by Lebron, Maria B, Brennan, Laura, Damoci, Christopher B, Prewett, Marie C, O'Mahony, Marguerita, Duignan, Inga J, Credille, Kelly M, DeLigio, James T, Starodubtseva, Marina, Amatulli, Michael, Zhang, Yiwei, Schwartz, Kaben D, Burtrum, Douglas, Balderes, Paul, Persaud, Kris, Surguladze, David, Loizos, Nick, Paz, Keren, Kotanides, Helen

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