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Discovery of Potent, Orally Bioavailable Small-Molecule Inhibitors of the Human CCR2 Receptor
by
Doyon, Julien
,
Coesemans, Erwin
,
Boeckx, Staf
,
Buntinx, Mieke
,
Hermans, Bart
,
Van Wauwe, Jean P.
,
Gilissen, Ron A. H. J.
,
De Groot, Alex H. J.
,
Corens, David
,
Van Lommen, Guy
Published in
ChemMedChem
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Chemmedchem
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Administration, Oral
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Animals
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Bioisosteres
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Biological Availability
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Calcium - Metabolism
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Ccr2
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Cell Line
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Chemistry, Medicinal
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Chemokine Ccl2 - Antagonists & Inhibitors
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Drug Stability
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Humans
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Imidazoles - Chemical Synthesis
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Imidazoles - Pharmacokinetics
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Inhibitors
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Life Sciences & Biomedicine
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Male
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Mcp-1
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Mcp‐1
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Pharmacology & Pharmacy
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