Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors by Beyett, Tyler S., To, Ciric, Heppner, David E., Rana, Jaimin K., Schmoker, Anna M., Jang, Jaebong, De Clercq, Dries J. H., Gomez, Gabriel, Scott, David A., Gray, Nathanael S., Jänne, Pasi A., Eck, Michael J.

Get full text

Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor by Jang, Jaebong, Son, Jieun, Park, Eunyoung, Kosaka, Takayuki, Saxon, Jamie A., De Clercq, Dries J. H., Choi, Hwan Geun, Tanizaki, Junko, Eck, Michael J., Jänne, Pasi A., Gray, Nathanael S.

Get full text

Kinase Substrate Sensor (KISS), a Mammalian In Situ Protein Interaction Sensor by Lievens, Sam, Gerlo, Sarah, Lemmens, Irma, De Clercq, Dries J.H., Risseeuw, Martijn D.P., Vanderroost, Nele, De Smet, Anne-Sophie, Ruyssinck, Elien, Chevet, Eric, Van Calenbergh, Serge, Tavernier, Jan

Get full text

Mutant‐Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug‐Resistant Mutations by Jang, Jaebong, To, Ciric, De Clercq, Dries J. H., Park, Eunyoung, Ponthier, Charles M., Shin, Bo Hee, Mushajiang, Mierzhati, Nowak, Radosław P., Fischer, Eric S., Eck, Michael J., Jänne, Pasi A., Gray, Nathanael S.

Get full text

Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors by De Clercq, Dries J. H, Heppner, David E, To, Ciric, Jang, Jaebong, Park, Eunyoung, Yun, Cai-Hong, Mushajiang, Mierzhati, Shin, Bo Hee, Gero, Thomas W, Scott, David A, Jänne, Pasi A, Eck, Michael J, Gray, Nathanael S

Get full text

Proteome-scale Binary Interactomics in Human Cells by Lievens, Sam, Van der Heyden, José, Masschaele, Delphine, De Ceuninck, Leentje, Petta, Ioanna, Gupta, Surya, De Puysseleyr, Veronic, Vauthier, Virginie, Lemmens, Irma, De Clercq, Dries J.H., Defever, Dieter, Vanderroost, Nele, De Smet, Anne-Sophie, Eyckerman, Sven, Van Calenbergh, Serge, Martens, Lennart, De Bosscher, Karolien, Libert, Claude, Hill, David E., Vidal, Marc, Tavernier, Jan

Get full text

Chemical Dimerizers in Three-Hybrid Systems for Small Molecule–Target Protein Profiling by De Clercq, Dries J. H, Tavernier, Jan, Lievens, Sam, Van Calenbergh, Serge

Get full text

Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor by To, Ciric, Jang, Jaebong, Chen, Ting, Park, Eunyoung, Mushajiang, Mierzhati, De Clercq, Dries J H, Xu, Man, Wang, Stephen, Cameron, Michael D, Heppner, David E, Shin, Bo Hee, Gero, Thomas W, Yang, Annan, Dahlberg, Suzanne E, Wong, Kwok-Kin, Eck, Michael J, Gray, Nathanael S, Jänne, Pasi A

Get full text

A "Clickable" MTX Reagent as a Practical Tool for Profiling Small-Molecule-Intracellular Target Interactions via MASPIT by Risseeuw, Martijn D. P., De Clercq, Dries J. H., Lievens, Sam, Hillaert, Ulrik, Sinnaeve, Davy, Van den Broeck, Freya, Martins, José C., Tavernier, Jan, Van Calenbergh, Serge

Get full text

Alternative Reagents for Methotrexate as Immobilizing Anchor Moieties in the Optimization of MASPIT: Synthesis and Biological Evaluation by De Clercq, Dries J. H., Risseeuw, Martijn D. P., Karalic, Izet, De Smet, Anne-Sophie, Defever, Dieter, Tavernier, Jan, Lievens, Sam, Van Calenbergh, Serge

Get full text

Mutant‐Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug‐Resistant Mutations by Jang, Jaebong, To, Ciric, De Clercq, Dries J. H., Park, Eunyoung, Ponthier, Charles M., Shin, Bo Hee, Mushajiang, Mierzhati, Nowak, Radosław P., Fischer, Eric S., Eck, Michael J., Jänne, Pasi A., Gray, Nathanael S.

Get full text

Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor by Jang, Jaebong, Son, Jieun, Park, Eunyoung, Kosaka, Takayuki, Saxon, Jamie A., De Clercq, Dries J. H., Choi, Hwan Geun, Tanizaki, Junko, Eck, Michael J., Jänne, Pasi A., Gray, Nathanael S.

Get full text