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An AAV capsid increases transduction of striatum and a ChAT promoter allows selective cholinergic neuron transduction
by
Santoscoy, Miguel C.
,
Espinoza, Paula
,
De La Cruz, Demitri
,
Mahamdeh, Mohammed
,
Starr, Jacqueline R.
,
Patel, Nikita
,
Maguire, Casey A.
Published in
Molecular therapy. Methods & clinical development
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Metabolic engineering improves transduction efficiency and downstream vector isolation by altering the lipid composition of extracellular vesicle-enclosed AAV
by
Espinoza, Paula
,
Cheng, Ming
,
Ng, Carrie
,
Cruz, Demitri de la
,
Wasson, Elizabeth D.
,
McCarthy, Deirdre M.
,
Bhide, Pradeep G.
,
Maguire, Casey A.
,
Santoscoy, Miguel C.
Published in
Metabolic engineering
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Metabolic Engineering
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Molecular Therapy. Methods & Clinical Development
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Aav
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Adeno-Associated Virus Vector
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Brain
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Cell-Type Specific Promoter
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Cholinergic Neurons
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Downstream
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Ev-Aav
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Gene Delivery
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Gene Therapy
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Life Sciences & Biomedicine
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Medicine, Research & Experimental
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Membrane Engineering
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Original
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Research & Experimental Medicine
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Science & Technology
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Striatum
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Target Gene Expression
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Transduction
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