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High tolerance to simultaneous active‐site mutations in TEM‐1 β‐lactamase: Distinct mutational paths provide more generalized β‐lactam recognition
by
De Wals, Pierre‐Yves
,
Doucet, Nicolas
,
Pelletier, Joelle N.
Published in
Protein science
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Site-saturation mutagenesis of Tyr-105 reveals its importance in substrate stabilization and discrimination in TEM-1 beta-lactamase
by
Doucet, Nicolas
,
De Wals, Pierre-Yves
,
Pelletier, Joelle N
Published in
The Journal of biological chemistry
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Site-saturation Mutagenesis of Tyr-105 Reveals Its Importance in Substrate Stabilization and Discrimination in TEM-1 β-Lactamase
by
Nicolas Doucet
,
Pierre-Yves De Wals
,
Joelle N. Pelletier
Published in
The Journal of biological chemistry
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The Journal Of Biological Chemistry
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Protein Science
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Subjects
Beta-Lactamases - Metabolism
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Biochemistry & Molecular Biology
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Life Sciences & Biomedicine
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Microbial Sensitivity Tests
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Models, Molecular
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Science & Technology
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Antibiotic Resistance
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Beta-Lactam Resistance - Genetics
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Beta-Lactam Resistance - Physiology
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Beta-Lactamases
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Beta-Lactamases - Chemistry
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Beta-Lactamases - Genetics
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Beta-Lactams - Pharmacokinetics
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Binding Sites
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Biochemistry, Molecular Biology
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Catalytic Domain - Genetics
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Catalytic Domain - Physiology
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Cefotaxime - Pharmacokinetics
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Combinatorial Mutagenesis
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Computer Simulation
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Full-Text Journals In Chemistry (Open Access)
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Ezb Electronic Journals Library
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Wiley-Blackwell Journals
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Wiley-Blackwell Open Access Collection
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Bacon - Elsevier - Global Sciencedirect-Openaccess
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Elsevier
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Doaj Directory Of Open Access Journals
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Wiley
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