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Low-Zone IL-2 Signaling: Fusion Proteins Containing Linked CD25 and IL-2 Domains Sustain Tolerogenic Vaccination in vivo and Promote Dominance of FOXP3 + Tregs in vitro
by
DeOca, Kayla B
,
Moorman, Cody D
,
Garcia, Brandon L
,
Mannie, Mark D
Published in
Frontiers in immunology
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A GM-CSF-neuroantigen tolerogenic vaccine elicits inefficient antigen recognition events below the CD40L triggering threshold to expand CD4 + CD25 + FOXP3 + Tregs that inhibit expe...
by
Moorman, Cody D
,
Bastian, Alexander G
,
DeOca, Kayla B
,
Mannie, Mark D
Published in
Journal of neuroinflammation
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Soluble CD25 imposes a low-zone IL-2 signaling environment that favors competitive outgrowth of antigen-experienced CD25high regulatory and memory T cells
by
Nickle, Rebecca A.
,
DeOca, Kayla B.
,
Garcia, Brandon L.
,
Mannie, Mark D.
Published in
Cellular immunology
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Tolerogenic vaccines: Targeting the antigenic and cytokine niches of FOXP3+ regulatory T cells
by
Mannie, Mark D.
,
DeOca, Kayla B.
,
Bastian, Alexander G.
,
Moorman, Cody D.
Published in
Cellular immunology
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Soluble CD25 imposes a low-zone IL-2 signaling environment that favors competitive outgrowth of antigen-experienced CD25 high regulatory and memory T cells
by
Nickle, Rebecca A
,
DeOca, Kayla B
,
Garcia, Brandon L
,
Mannie, Mark D
Published in
Cellular immunology
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