Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain‐like Protease PLpro by Gil‐Moles, Maria, Türck, Sebastian, Basu, Uttara, Pettenuzzo, Andrea, Bhattacharya, Saurav, Rajan, Ananthu, Ma, Xiang, Büssing, Rolf, Wölker, Jessica, Burmeister, Hilke, Hoffmeister, Henrik, Schneeberg, Pia, Prause, Andre, Lippmann, Petra, Kusi‐Nimarko, Josephine, Hassell‐Hart, Storm, McGown, Andrew, Guest, Daniel, Lin, Yan, Notaro, Anna, Vinck, Robin, Karges, Johannes, Cariou, Kevin, Peng, Kun, Qin, Xue, Wang, Xing, Skiba, Joanna, Szczupak, Łukasz, Kowalski, Konrad, Schatzschneider, Ulrich, Hemmert, Catherine, Gornitzka, Heinz, Milaeva, Elena R., Nazarov, Alexey A., Gasser, Gilles, Spencer, John, Ronconi, Luca, Kortz, Ulrich, Cinatl, Jindrich, Bojkova, Denisa, Ott, Ingo

Get full text

Sars-Cov-2 Fails to Infect Mesenchymal Stromal Cells (MSCs) - Pre-Clinical Investigations in Support of Therapeutic Use of MSCs for Severe COVID-19 by Pfeffermann, Lisa-Marie, Bojkova, Denisa, Kandler, Joshua, Huenecke, Sabine, Bremm, Melanie, Piede, Natascha, Kuci, Selim, Kuci, Zyrafete, Harenkamp, Sabine, Bonig, Halvard, Bader, Peter

Get full text

Synergism of interferon-beta with antiviral drugs against SARS-CoV-2 variants by Bojkova, Denisa, Stack, Richard, Rothenburger, Tamara, Kandler, Joshua D., Ciesek, Sandra, Wass, Mark N., Michaelis, Martin, Cinatl, Jindrich

Get full text

The SARS-CoV-2 main protease M.sup.pro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells by Wenzel, Jan, Lampe, Josephine, Müller-Fielitz, Helge, Schuster, Raphael, Zille, Marietta, Müller, Kristin, Krohn, Markus, Korbelin, Jakob, Zhang, Linlin, Ozorhan, Umit, Neve, Vanessa, Wagner, Julian U.G, Bojkova, Denisa

Get full text

Omicron‐induced interferon signaling prevents influenza A H1N1 and H5N1 virus infection by Bojkova, Denisa, Bechtel, Marco, Rothenburger, Tamara, Kandler, Joshua D., Hayes, Lauren, Olmer, Ruth, Martin, Ulrich, Jonigk, Danny, Ciesek, Sandra, Wass, Mark N., Michaelis, Martin, Cinatl, Jindrich

Get full text

Silver N-heterocyclic carbene complexes are potent uncompetitive inhibitors of the papain-like protease with antiviral activity against SARS-CoV-2 by Gil-Moles, Maria, O'Beirne, Cillian, Esarev, Igor V, Lippmann, Petra, Tacke, Matthias, Cinatl, Jindrich, Bojkova, Denisa, Ott, Ingo

Get full text

Identification of Natural Products Inhibiting SARS-CoV‑2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach by Wasilewicz, Andreas, Kirchweger, Benjamin, Bojkova, Denisa, Abi Saad, Marie Jose, Langeder, Julia, Bütikofer, Matthias, Adelsberger, Sigrid, Grienke, Ulrike, Cinatl Jr, Jindrich, Petermann, Olivier, Scapozza, Leonardo, Orts, Julien, Kirchmair, Johannes, Rabenau, Holger F., Rollinger, Judith M.

Get full text

Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In-Vitro SARS-CoV-2 Infection by de Bruin, Natasja, Schneider, Ann-Kathrin, Reus, Philipp, Talmon, Sonja, Ciesek, Sandra, Bojkova, Denisa, Cinatl, Jindrich, Lodhi, Imran, Charlesworth, Bruce, Sinclair, Simon, Pennick, Graham, Laughey, William F, Gribbon, Philip, Kannt, Aimo, Schiffmann, Susanne

Get full text

Correction: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies by Armstrong, Lee A, Lange, Sven M, Cesare, Virginia De, Matthews, Stephen P, Nirujogi, Raja Sekhar, Cole, Isobel, Hope, Anthony, Cunningham, Fraser, Toth, Rachel, Mukherjee, Rukmini, Bojkova, Denisa, Gruber, Franz, Gray, David, Wyatt, Paul G, Cinatl, Jindrich, Dikic, Ivan, Davies, Paul, Kulathu, Yogesh

Get full text

Drug repurposing for the treatment of COVID-19: Targeting nafamostat to the lungs by a liposomal delivery system by Reus, Philipp, Guthmann, Hadar, Uhlig, Nadja, Agbaria, Majd, Issmail, Leila, Eberlein, Valentina, Nordling-David, Mirjam M, Jbara-Agbaria, Doaa, Ciesek, Sandra, Bojkova, Denisa, Cinatl, Jindrich, Burger-Kentischer, Anke, Rupp, Steffen, Zaliani, Andrea, Grunwald, Thomas, Gribbon, Philip, Kannt, Aimo, Golomb, Gershon

Get full text

Repurposing of the antibiotic nitroxoline for the treatment of mpox by Bojkova, Denisa, Zöller, Nadja, Tietgen, Manuela, Steinhorst, Katja, Bechtel, Marco, Rothenburger, Tamara, Kandler, Joshua D., Schneider, Julia, Corman, Victor M., Ciesek, Sandra, Rabenau, Holger F., Wass, Mark N., Kippenberger, Stefan, Göttig, Stephan, Michaelis, Martin, Cinatl, Jindrich

Get full text

Development and optimization of a high‐throughput screening assay for in vitro anti‐SARS‐CoV‐2 activity: Evaluation of 5676 Phase 1 Passed Structures by Chiu, Winston, Verschueren, Lore, Van den Eynde, Christel , Buyck, Christophe, De Meyer, Sandra, Jochmans, Dirk, Bojkova, Denisa, Ciesek, Sandra, Cinatl, Jindrich, De Jonghe, Steven, Leyssen, Pieter, Neyts, Johan, Van Loock, Marnix, Van Damme, Ellen

Get full text

Differentially conserved amino acid positions may reflect differences in SARS-CoV-2 and SARS-CoV behaviour by Bojkova, Denisa, McGreig, Jake E, McLaughlin, Katie-May, Masterson, Stuart G, Antczak, Magdalena, Widera, Marek, Krähling, Verena, Ciesek, Sandra, Wass, Mark N, Michaelis, Martin, Cinatl, Jindrich

Request full text

SEC14L2, a lipid-binding protein, regulates HCV replication in culture with inter- and intra-genotype variations by Costa, Rui, Todt, Daniel, Zapatero-Belinchón, Francisco, Schenk, Christian, Anastasiou, Olympia E., Walker, Andreas, Hertel, Barbara, Timmer, Lejla, Bojkova, Denisa, Ruckert, Maren, Sarrazin, Christoph, Timm, Jörg, Lohmann, Volker, Manns, Michael P., Steinmann, Eike, von Hahn, Thomas, Ciesek, Sandra

Get full text

Methylene Blue Treatment of Grafts During Cold Ischemia Time Reduces the Risk of Hepatitis C Virus Transmission by Helfritz, Fabian A, Bojkova, Denisa, Wanders, Verena, Kuklinski, Nina, Westhaus, Sandra, von Horn, Charlotte, Rauen, Ursula, Gallinat, Anja, Baba, Hideo A, Skyschally, Andreas, Swoboda, Sandra, Kinast, Volker, Steinmann, Eike, Heusch, Gerd, Minor, Thomas, Meuleman, Philip, Paul, Andreas, Ciesek, Sandra

Get full text

Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PL pro by Gil-Moles, Maria, Türck, Sebastian, Basu, Uttara, Pettenuzzo, Andrea, Bhattacharya, Saurav, Rajan, Ananthu, Ma, Xiang, Büssing, Rolf, Wölker, Jessica, Burmeister, Hilke, Hoffmeister, Henrik, Schneeberg, Pia, Prause, Andre, Lippmann, Petra, Kusi-Nimarko, Josephine, Hassell-Hart, Storm, McGown, Andrew, Guest, Daniel, Lin, Yan, Notaro, Anna, Vinck, Robin, Karges, Johannes, Cariou, Kevin, Peng, Kun, Qin, Xue, Wang, Xing, Skiba, Joanna, Szczupak, Łukasz, Kowalski, Konrad, Schatzschneider, Ulrich, Hemmert, Catherine, Gornitzka, Heinz, Milaeva, Elena R, Nazarov, Alexey A, Gasser, Gilles, Spencer, John, Ronconi, Luca, Kortz, Ulrich, Cinatl, Jindrich, Bojkova, Denisa, Ott, Ingo

Get full text

Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the Spike/ACE2 interaction and the Papain‐like Protease PLpro by Gil-Moles, Maria, Türck, Sebastian, Basu, Uttara, Pettenuzzo, Andrea, Bhattacharya, Saurav, Rajan, Ananthu, Ma, Xiang, Büssing, Rolf, Wölker, Jessica, Burmeister, Hilke, Hoffmeister, Henrik, Schneeberg, Pia, Prause, Andre, Lippmann, Petra, Kusi-Nimarko, Josephine, Hassell-Hart, Storm, Mcgown, Andrew, Guest, Daniel, Lin, Yan, Notaro, Anna, Vinck, Robin, Karges, Johannes, Cariou, Kevin, Peng, Kun, Qin, Xue, Wang, Xing, Skiba, Joanna, Szczupak, Łukasz, Kowalski, Konrad, Schatzschneider, Ulrich, Hemmert, Catherine, Gornitzka, Heinz, Milaeva, Elena R, Nazarov, Alexey A, Gasser, Gilles, Spencer, John, Ronconi, Luca, Kortz, Ulrich, Cinatl, Jindrich, Bojkova, Denisa, Ott, Ingo

Get full text

Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19... by Cremer, Sebastian, Pilgram, Lisa, Berkowitsch, Alexander, Stecher, Melanie, Rieg, Siegbert, Shumliakivska, Mariana, Bojkova, Denisa, Wagner, Julian Uwe Gabriel, Aslan, Galip Servet, Spinner, Christoph, Luxán, Guillermo, Hanses, Frank, Dolff, Sebastian, Piepel, Christiane, Ruppert, Clemens, Guenther, Andreas, Rüthrich, Maria Madeleine, Vehreschild, Jörg Janne, Wille, Kai, Haselberger, Martina, Heuzeroth, Hanno, Hansen, Arne, Eschenhagen, Thomas, Cinatl, Jindrich, Ciesek, Sandra, Dimmeler, Stefanie, Borgmann, Stefan, Zeiher, Andreas

Get full text

A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization by Schultz, Bruce, Zaliani, Andrea, Ebeling, Christian, Reinshagen, Jeanette, Bojkova, Denisa, Lage-Rupprecht, Vanessa, Karki, Reagon, Lukassen, Sören, Gadiya, Yojana, Ravindra, Neal G., Das, Sayoni, Baksi, Shounak, Domingo-Fernández, Daniel, Lentzen, Manuel, Strivens, Mark, Raschka, Tamara, Cinatl, Jindrich, DeLong, Lauren Nicole, Gribbon, Phil, Geisslinger, Gerd, Ciesek, Sandra, van Dijk, David, Gardner, Steve, Kodamullil, Alpha Tom, Fröhlich, Holger, Peitsch, Manuel, Jacobs, Marc, Hoeng, Julia, Eils, Roland, Claussen, Carsten, Hofmann-Apitius, Martin

Get full text

Infectivity and stability of hepatitis C virus in different perfusion solutions by Helfritz, Fabian A., Wanders, Verena, Bojkova, Denisa, Kuklinski, Nina, Westhaus, Sandra, Swoboda, Sandra, Minor, Thomas, Meuleman, Philip, Paul, Andreas, Steinmann, Eike, Ciesek, Sandra

Get full text