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Search Results - Denissen, Jon
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Metabolism and disposition of the HIV-1 protease inhibitor lopinavir (ABT-378) given in combination with ritonavir in rats, dogs, and humans
by
Kumar, Gondi N
,
Jayanti, Venkata K
,
Johnson, Marianne K
,
Uchic, John
,
Thomas, Samuel
,
Lee, Ronald D
,
Grabowski, Brian A
,
Sham, Hing L
,
Kempf, Dale J
,
Denissen, Jon F
,
Marsh, Kennan C
,
Sun, Eugene
,
Roberts, Stanley A
Published in
Pharmaceutical research
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ABT-538 is a Potent Inhibitor of Human Immunodeficiency Virus Protease and has High Oral Bioavailability in Humans
by
Kempf, Dale J.
,
Marsh, Kennan C.
,
Denissen, Jon F.
,
McDonald, Edith
,
Vasavanonda, Sudthida
,
Flentge, Charles A.
,
Green, Brian E.
,
Fino, Lynnmarie
,
Park, Chang H.
,
Kong, Xiang-Peng
,
Wideburg, Norman E.
,
Saldivar, Ayda
,
Ruiz, Lisa
,
Kati, Warren M.
,
Sham, Hing L.
,
Robins, Terry
,
Stewart, Kent D.
,
Hsu, Ann
,
Plattner, Jacob J.
,
Leonard, John M.
,
Norbeck, Daniel W.
Published in
Proceedings of the National Academy of Sciences - PNAS
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Human Serum Attenuates the Activity of Protease Inhibitors toward Wild-Type and Mutant Human Immunodeficiency Virus
by
Molla, Akhteruzzaman
,
Vasavanonda, Sudthida
,
Kumar, Gondi
,
Sham, Hing L.
,
Johnson, Marianne
,
Grabowski, Brian
,
Denissen, Jon F.
,
Kohlbrenner, William
,
Plattner, Jacob J.
,
Leonard, John M.
,
Norbeck, Daniel W.
,
Kempf, Dale J.
Published in
Virology (New York, N.Y.)
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A Novel, Picomolar Inhibitor of Human Immunodeficiency Virus Type 1 Protease
by
Sham, Hing L
,
Zhao, Chen
,
Stewart, Kent D
,
Betebenner, David A
,
Lin, Shuqun
,
Park, Chang H
,
Kong, Xiang-P
,
Rosenbrook, William
,
Herrin, Thomas
,
Madigan, Darold
,
Vasavanonda, Suthida
,
Lyons, Nicholas
,
Molla, Akhter
,
Saldivar, Ayda
,
Marsh, Kennan C
,
McDonald, Edith
,
Wideburg, Norman E
,
Denissen, Jon F
,
Robins, Terrel
,
Kempf, Dale J
,
Plattner, Jacob J
,
Norbeck, Daniel W
Published in
Journal of medicinal chemistry
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Two-injection workflow for a liquid chromatography/LTQ-Orbitrap system to complete in vivo biotransformation characterization: demonstration with buspirone metabolite identificatio...
by
Li, Austin C.
,
Ding, Jie
,
Jiang, Xiangyu
,
Denissen, Jon
Published in
Rapid communications in mass spectrometry
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Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir
by
KEMPF, D. J
,
MARSH, K. C
,
SUN, E
,
PIZZUTI, D
,
PLATTNER, J. J
,
NORBECK, D. W
,
LEONARD, J. M
,
KUMAR, G
,
RODRIGUES, A. D
,
DENISSEN, J. F
,
MCDONALD, E
,
KUKULKA, M. J
,
HSU, A
,
GRANNEMAN, G. R
,
BAROLDI, P. A
Published in
Antimicrobial Agents and Chemotherapy
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Discovery and Evaluation of a Series of 3-Acylindole Imidazopyridine Platelet-Activating Factor Antagonists
by
Curtin, Michael L
,
Davidsen, Steven K
,
Heyman, H. Robin
,
Garland, Robert B
,
Sheppard, George S
,
Florjancic, Alan S
,
Xu, Lianhong
,
Carrera, George M
,
Steinman, Douglas H
,
Trautmann, Jeff A
,
Albert, Daniel H
,
Magoc, Terrance J
,
Tapang, Paul
,
Rhein, David A
,
Conway, Richard G
,
Luo, Gongjin
,
Denissen, Jon F
,
Marsh, Kennan C
,
Morgan, Douglas W
,
Summers, James B
Published in
Journal of medicinal chemistry
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Multiple-dose pharmacokinetics of ritonavir in human immunodeficiency virus-infected subjects
by
HSU, A
,
GRANNEMAN, G. R
,
NIU, P
,
DECOURT, J.-P
,
FOURTILLAN, J.-B
,
GIRAULT, J
,
LEONARD, J. M
,
WITT, G
,
LOCKE, C
,
DENISSEN, J
,
MOLLA, A
,
VALDES, J
,
SMITH, J
,
ERDMAN, K
,
LYONS, N
Published in
Antimicrobial Agents and Chemotherapy
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Identification of .alpha.-santalenoic and endo-.beta.-bergamotenoic acids as moth oviposition stimulants from wild tomato leaves
by
Coates, Robert M
,
Denissen, Jon F
,
Juvik, John A
,
Babka, Barbara A
Published in
Journal of organic chemistry
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Discovery of a Well-Absorbed, Efficacious Renin Inhibitor, A-74273
by
Kleinert, Hollis D
,
Stein, Herman H
,
Boyd, Steven
,
Fung, Anthony K.L
,
Baker, William R
,
Verburg, Kenneth M
,
Polakowski, James S
,
Kovar, Peter
,
Barlow, Jennifer
,
Cohen, Jerome
,
Klinghofer, Vered
,
Mantei, Robert
,
Cepa, Steven
,
Rosenberg, Saul
,
Denissen, Jon F
Published in
Hypertension (Dallas, Tex. 1979)
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Preparative separation of the enantiomers of the cholecystokinin antagonist (3 S)-(±)-N-(2,3-dihydro-1-([ 3H 3]methyl)-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-yl)-1H-indole-2-carbox...
by
Denissen, Jon F.
Published in
Journal of Chromatography A
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Geminal dimethyl stereochemistry in the enzymic cyclization of geranyl pyrophosphate to (+)- and (-)-.alpha.-pinene
by
Coates, Robert M
,
Denissen, Jon F
,
Croteau, Rodney B
,
Wheeler, Carl J
Published in
Journal of the American Chemical Society
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Discovery of a Peptide-Based Renin Inhibitor with Oral Bioavailability and Efficacy
by
Kleinert, Hollis D.
,
Rosenberg, Saul H.
,
Baker, William R.
,
Stein, Herman H.
,
Klinghofer, Vered
,
Barlow, Jennifer
,
Spina, Kenneth
,
Polakowski, James
,
Kovar, Peter
,
Cohen, Jerome
,
Denissen, Jon
Published in
Science (American Association for the Advancement of Science)
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Nonpeptide Renin Inhibitors with Good Intraduodenal Bioavailability and Efficacy in Dog
by
Boyd, Steven A
,
Fung, Anthony K. L
,
Baker, William R
,
Mantei, Robert A
,
Stein, Herman H
,
Cohen, Jerome
,
Barlow, Jennifer L
,
Klinghofer, Vered
,
Wessale, Jerry L
Published in
Journal of medicinal chemistry
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Geminal dimethyl stereochemistry in the enzymatic cyclization of geranyl pyrophosphate to (+)- and (-)-α-pinene
by
COATES, R. M
,
DENISSEN, J. F
,
CROTEAU, R. B
,
WHEELER, C. J
Published in
Journal of the American Chemical Society
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