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Abstract 5286: A pipeline for developing a novel, predictive tool to classify variants of uncertain significance (VUS) in Lynch Syndrome
by
Arora, Sanjeevani
,
Huwe, Peter J.
,
Sikder, Rahmat
,
Shah, Manali
,
Deshpande, Sanat
,
Hall, Michael J.
,
Dunbrack, Roland L.
,
Golemis, Erica A.
Published in
Cancer research (Chicago, Ill.)
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Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods
by
Arora, Sanjeevani
,
Huwe, Peter J.
,
Sikder, Rahmat
,
Shah, Manali
,
Browne, Amanda J.
,
Lesh, Randy
,
Nicolas, Emmanuelle
,
Deshpande, Sanat
,
Hall, Michael J.
,
Dunbrack, Roland L.
,
Golemis, Erica A.
Published in
Cancer biology & therapy
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Cancer Biology & Therapy
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Cancer Research
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Amino Acid Substitution
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Biomarkers, Tumor
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Cell Survival - Genetics
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Colon Cancer
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Colorectal Cancer Predisposition
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Colorectal Neoplasms, Hereditary Nonpolyposis - Genetics
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Dna Damage
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Dna Mismatch Repair
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Dna-Binding Proteins - Chemistry
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Dna-Binding Proteins - Genetics
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Dna-Binding Proteins - Metabolism
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Female
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Gene Expression
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Genetic Variation
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Humans
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Life Sciences & Biomedicine
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Mismatch Repair
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Models, Molecular
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Molecular Conformation
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