Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer by Gainor, Justin F, Dardaei, Leila, Yoda, Satoshi, Friboulet, Luc, Leshchiner, Ignaty, Katayama, Ryohei, Dagogo-Jack, Ibiayi, Gadgeel, Shirish, Schultz, Katherine, Singh, Manrose, Chin, Emily, Parks, Melissa, Lee, Dana, DiCecca, Richard H, Lockerman, Elizabeth, Huynh, Tiffany, Logan, Jennifer, Ritterhouse, Lauren L, Le, Long P, Muniappan, Ashok, Digumarthy, Subba, Channick, Colleen, Keyes, Colleen, Getz, Gad, Dias-Santagata, Dora, Heist, Rebecca S, Lennerz, Jochen, Sequist, Lecia V, Benes, Cyril H, Iafrate, A John, Mino-Kenudson, Mari, Engelman, Jeffrey A, Shaw, Alice T

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Primary Patient-Derived Cancer Cells and Their Potential for Personalized Cancer Patient Care by Kodack, David P., Farago, Anna F., Dastur, Anahita, Held, Matthew A., Dardaei, Leila, Friboulet, Luc, von Flotow, Friedrich, Damon, Leah J., Lee, Dana, Parks, Melissa, Dicecca, Richard, Greenberg, Max, Kattermann, Krystina E., Riley, Amanda K., Fintelmann, Florian J., Rizzo, Coleen, Piotrowska, Zofia, Shaw, Alice T., Gainor, Justin F., Sequist, Lecia V., Niederst, Matthew J., Engelman, Jeffrey A., Benes, Cyril H.

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Abstract A13: Development of a drug response assessment platform for biopsy-derived tumor models by Kodack, David P., Held, Matthew, Damon, Leah, Lee, Dana, Parks, Melissa, Dicecca, Richard, Greenberg, Max, Engelman, Jeffrey A., Benes, Cyril H.

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Abstract A145: SHP2 inhibition restores sensitivity to ALK inhibitors in resistant ALK-rearranged NSCLC by Dardaei, Leila, Wang, Hui Qin, Singh, Manrose, Fordjour, Paul, Yoda, Satoshi, Kerr, Grainne, Liang, Jinsheng, Cao, Yichen, Chen, Yan, Gainor, Justin, Friboulet, Luc, Dagogo-Jack, Ibiayi, Myers, David, Labrot, Emma, Ruddy, David, Parks, Melissa, Lee, Dana, DiCecca, Richard, Moody, Susan, Hao, Huaixiang, Mohseni, Morvarid, LaMarche, Matthew, Williams, Juliet, Hoffmaster, Keith, Caponigro, Giordano, Shaw, Alice, Hata, Aaron, Benes, Cyril, Li, Fang, Engelman, Jeffrey

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Abstract 1007: SHP2 inhibition restores sensitivity to ALK inhibition in resistant ALK-rearranged non-small cell lung cancer (NSCLC) by Dardaei, Leila, Wang, Hui Qin, Fordjour, Paul, Singh, Manrose, Kerr, Grainne, Yoda, Satoshi, Liang, Jinsheng, Cao, Yichen, Chen, Yan, Gainor, Justin F., Friboulet, Luc, Dagogo-Jack, Ibiayi, Myers, David T., Labrot, Emma, Ruddy, David, Parks, Melissa, Lee, Dana, DiCecca, Richard H., Moody, Susan, Hao, Huaixiang, Mohseni, Morvarid, LaMarche, Matthew, Williams, Juliet, Hoffmaster, Keith, Caponigro, Giordano, Benes, Cyril H., Shaw, Alice T., Hata, Aaron N., Li, Fang, Engelman, Jeffrey A.

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Heterogeneity Underlies the Emergence of EGFR T790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor by Piotrowska, Zofia, Niederst, Matthew J., Karlovich, Chris A., Wakelee, Heather A., Neal, Joel W., Mino-Kenudson, Mari, Fulton, Linnea, Hata, Aaron N., Lockerman, Elizabeth L., Kalsy, Anuj, Digumarthy, Subba, Muzikansky, Alona, Raponi, Mitch, Garcia, Angel R., Mulvey, Hillary E., Parks, Melissa K., DiCecca, Richard H., Dias-Santagata, Dora, Iafrate, A. John, Shaw, Alice T., Allen, Andrew R., Engelman, Jeffrey A., Sequist, Lecia V.

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Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor by Piotrowska, Zofia, Niederst, Matthew J, Karlovich, Chris A, Wakelee, Heather A, Neal, Joel W, Mino-Kenudson, Mari, Fulton, Linnea, Hata, Aaron N, Lockerman, Elizabeth L, Kalsy, Anuj, Digumarthy, Subba, Muzikansky, Alona, Raponi, Mitch, Garcia, Angel R, Mulvey, Hillary E, Parks, Melissa K, DiCecca, Richard H, Dias-Santagata, Dora, Iafrate, A John, Shaw, Alice T, Allen, Andrew R, Engelman, Jeffrey A, Sequist, Lecia V

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