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Matrix metalloproteinase–activated doxorubicin prodrugs inhibit HT1080 xenograft growth better than doxorubicin with less toxicity
by
Albright, Charles F
,
Graciani, Nilsa
,
Han, Wei
,
Yue, Eddy
,
Stein, Ross
,
Lai, Zhihong
,
Diamond, Melody
,
Dowling, Randine
,
Grimminger, Lisa
,
Zhang, Shu-Yun
,
Behrens, Davette
,
Musselman, Amy
,
Bruckner, Robert
,
Zhang, Mingzhu
,
Jiang, Xiang
,
Hu, Daniel
,
Higley, Anne
,
Dimeo, Susan
,
Rafalski, Maria
,
Mandlekar, Sandya
,
Car, Bruce
,
Yeleswaram, Swamy
,
Stern, Andrew
,
Copeland, Robert A
,
Combs, Andrew
,
Seitz, Steve P
,
Trainor, George L
,
Taub, Rebecca
,
Huang, Pearl
,
Oliff, Allen
Published in
Molecular cancer therapeutics
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Synthesis and Evaluation of Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors. 3. Structure Activity Relationships at C3
by
Yue, Eddy W
,
Higley, C. Anne
,
DiMeo, Susan V
,
Carini, David J
,
Nugiel, David A
,
Benware, Carrie
,
Benfield, Pamela A
,
Burton, Catherine R
,
Cox, Sarah
,
Grafstrom, Robert H
,
Sharp, Diane M
,
Sisk, Lisa M
,
Boylan, John F
,
Muckelbauer, Jodi K
,
Smallwood, Angela M
,
Chen, Haiying
,
Chang, Chong-Hwan
,
Seitz, Steven P
,
Trainor, George L
Published in
Journal of medicinal chemistry
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Development of a Scalable Synthesis toward a KRAS G12C Inhibitor Building Block Bearing an All-Carbon Quaternary Stereocenter, Part 2: Asymmetric Synthesis via Shi Epoxidation
by
Tan, Zhulin
,
Ju, Xuan
,
Wu, Hao
,
Dong, Weitong
,
Leung, Joyce C.
,
Hou, Xiaowen
,
Lee, Heewon
,
Granger, Alice
,
Paolillo, Joshua M.
,
DiMeo, Susan V.
,
Chen, Chengsheng
,
Wu, Linglin
,
Lorenz, Jon C.
,
Sarvestani, Max
,
Buono, Frederic
,
Frutos, Rogelio
,
Tampone, Thomas G.
,
Huang, Xiaojun
,
Zhang, Gulin
,
Wang, Yuwen
,
Spinelli, Earl
,
Lei, Zhen
,
Song, Jinhua J.
Published in
Organic process research & development
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Development of a Scalable Synthesis toward a KRAS G12C Inhibitor Building Block Bearing an All-Carbon Quaternary Stereocenter, Part 1: From Discovery Route to Kilogram-Scale Produc...
by
Leung, Joyce C.
,
Xu, Yibo
,
Radomkit, Suttipol
,
Lee, Jaehee
,
Kim, Wan Shin
,
Reeves, Jonathan T.
,
Dong, Weitong
,
Jang, Hwanjong
,
Hou, Xiaowen
,
Lorenz, Jon C.
,
Shao, Xiaole
,
Byrne, Denis
,
Johnson, Joe
,
Brundage, Anthony
,
Valentin, Clement
,
Beyer, Phouvieng
,
DiMeo, Susan V.
,
Qu, Bo
,
Li, Ruoshi
,
Sarvestani, Max
,
Song, Jinhua J.
Published in
Organic process research & development
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Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. Part 4: Heterocycles at C3
by
Yue, Eddy W.
,
DiMeo, Susan V.
,
Higley, C.Anne
,
Markwalder, Jay A.
,
Burton, Catherine R.
,
Benfield, Pamela A.
,
Grafstrom, Robert H.
,
Cox, Sarah
,
Muckelbauer, Jodi K.
,
Smallwood, Angela M.
,
Chen, Haiying
,
Chang, Chong-Hwan
,
Trainor, George L.
,
Seitz, Steven P.
Published in
Bioorganic & medicinal chemistry letters
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National outbreak of Acanthamoeba keratitis associated with use of a contact lens solution, United States
by
VERANI, J.R
,
LORICK, S.A
,
YODER, J.S
,
BEACH, M.J
,
BRADEN, C.R
,
ROBERTS, J.M
,
CONOVER, C.S
,
CHEN, S
,
MCCONNELL, K.A
,
CHANG, D.C
Published in
Emerging infectious diseases
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Micromachined chemical sensor with dual-transduction mechanisms
by
Chen, Ing-Shin
,
Stawasz, Michele
,
DiMascio, Susan K.
,
Welch, James J.
,
Neuner, Jeffrey W.
,
Chen, Philip S. H.
,
DiMeo, Frank
Published in
Applied physics letters
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(Imidazolylphenyl)pyrrol-2-one inhibitors of cardiac cAMP phosphodiesterase
by
Lampe, John W
,
Chou, Yuo Ling
,
Hanna, Reda G
,
Di Meo, Susan V
,
Erhardt, Paul W
,
Hagedorn, Alfred A
,
Ingebretsen, William R
,
Cantor, Elinor
Published in
Journal of medicinal chemistry
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Heteroaryl-Fused 2-Phenylisothiazolone Inhibitors of Cartilage Breakdown
by
Wright, Stephen W
,
Petraitis, Joseph J
,
Abelman, Matthew M
,
Batt, Douglas G
,
Bostrom, Lori L
,
Corbett, Ronald L
,
Decicco, Carl P
,
Di Meo, Susan V
,
Freimark, Bruce
Published in
Journal of medicinal chemistry
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Metabolism resistant isothiazolone inhibitors of cartilage breakdown
by
Wright, Stephen W.
,
Petraitis, Joseph J.
,
Batt, Douglas G.
,
Corbett, Ronald L.
,
Di Meo, Susan V.
,
Freimark, Bruce
,
Giannaras, John V.
,
Orwat, Michael J.
,
Pinto, Donald J.
,
Pratta, Michael A.
,
Sherk, Susan R.
,
Stampfli, Herman F.
,
Williams, Jean M.
,
Magolda, Ronald L.
,
Arner, Elizabeth C.
Published in
Bioorganic & medicinal chemistry
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Synthesis and cardiac electrophysiological activity of N-substituted-4-(1H-imidazol-1-yl)benzamides - new selective class III agents
by
Morgan, Thomas K
,
Lis, Randall
,
Lumma, William C
,
Nickisch, Klaus
,
Wohl, Ronald A
,
Phillips, Gary B
,
Gomez, Robert P
,
Lampe, John W
,
Di Meo, Susan V
Published in
Journal of medicinal chemistry
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Synthesis and pharmacological studies of N-[4-[2-hydroxy-3-[[2-[4-(1H-imidazol-1-yl)phenoxy]ethyl]amino]propoxy]phenyl]methanesulfonamide, a novel antiarrhythmic agent with class I...
by
Morgan, Thomas K
,
Lis, Randall
,
Lumma, William C
,
Wohl, Ronald A
,
Nickisch, Klaus
,
Phillips, Gary B
,
Lind, Joan M
,
Lampe, John W
,
Di Meo, Susan V
Published in
Journal of medicinal chemistry
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