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Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design
by
Hughes, Norman E.
,
Bleisch, Thomas J.
,
Jones, Scott A.
,
Richardson, Timothy I.
,
Doti, Robert A.
,
Wang, Yong
,
Stout, Stephanie L.
,
Durst, Gregory L.
,
Chambers, Mark G.
,
Oskins, Jennifer L.
,
Lin, Chaohua
,
Adams, Lisa A.
,
Page, Todd J.
,
Barr, Robert J.
,
Zink, Richard W.
,
Osborne, Harold
,
Montrose-Rafizadeh, Chahrzad
,
Norman, Bryan H.
Published in
Bioorganic & medicinal chemistry letters
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Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists
by
Burkholder, Timothy P.
,
Cunningham, Brian E.
,
Clayton, Joshua R.
,
Lander, Peter A.
,
Brown, Matthew L.
,
Doti, Robert A.
,
Durst, Gregory L.
,
Montrose-Rafizadeh, Chahrzad
,
King, Constance
,
Osborne, Harold E.
,
Amos, Robert M.
,
Zink, Richard W.
,
Stramm, Lawrence E.
,
Burris, Thomas P.
,
Cardona, Guemalli
,
Konkol, Debra L.
,
Reidy, Charles
,
Christe, Michael E.
,
Genin, Michael J.
Published in
Bioorganic & medicinal chemistry letters
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3,3-Bisaryloxindoles as mineralocorticoid receptor antagonists
by
Neel, David A.
,
Brown, Matthew L.
,
Lander, Peter A.
,
Grese, Timothy A.
,
Defauw, Jean M.
,
Doti, Robert A.
,
Fields, Todd
,
Kelley, Sally Ann
,
Smith, Stephon
,
Zimmerman, Karen M.
,
Steinberg, Mitchell I.
,
Jadhav, Prabhakar K.
Published in
Bioorganic & medicinal chemistry letters
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Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design
by
Hughes, Norman E.
,
Bleisch, Thomas J.
,
Jones, Scott A.
,
Richardson, Timothy I.
,
Doti, Robert A.
,
Wang, Yong
,
Stout, Stephanie L.
,
Durst, Gregory L.
,
Chambers, Mark G.
,
Oskins, Jennifer L.
,
Lin, Chaohua
,
Adams, Lisa A.
,
Page, Todd J.
,
Barr, Robert J.
,
Zink, Richard W.
,
Osborne, Harold
,
Montrose-Rafizadeh, Chahrzad
,
Norman, Bryan H.
Published in
Bioorganic & medicinal chemistry letters
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Discovery of Potent, Selective, and Orally Active Carboxylic Acid Based Inhibitors of Matrix Metalloproteinase-13
by
Monovich, Lauren G
,
Tommasi, Ruben A
,
Fujimoto, Roger A
,
Blancuzzi, Vincent
,
Clark, Kirk
,
Cornell, Wendy D
,
Doti, Robert
,
Doughty, John
,
Fang, James
,
Farley, David
,
Fitt, John
,
Ganu, Vishwas
,
Goldberg, Ronald
,
Goldstein, Robert
,
Lavoie, Stacey
,
Kulathila, Raviraj
,
Macchia, William
,
Parker, David T
,
Melton, Richard
,
O’Byrne, Elizabeth
,
Pastor, Gary
,
Pellas, Theodore
,
Quadros, Elizabeth
,
Reel, Noela
,
Roland, Dennis M
,
Sakane, Yumi
,
Singh, Hem
,
Skiles, Jerry
,
Somers, Joseph
,
Toscano, Karen
,
Wigg, Andrew
,
Zhou, Siyuan
,
Zhu, Lijuan
,
Shieh, Wen-Chung
,
Xue, Song
,
McQuire, Leslie W
Published in
Journal of medicinal chemistry
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Simultaneous determination of enantiomeric purity and erythro/ threo relationship in chiral 1,2-aminoalcohols by NMR using ( R)-(+)- t-butylphenylphosphinothioic acid
by
Gunderson, Karl G
,
Shapiro, Michael J
,
Doti, Robert A
,
Skiles, Jerry W
Published in
Tetrahedron: asymmetry
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Carboxy-Substituted Cinnamides: A Novel Series of Potent, Orally Active LTB4 Receptor Antagonists
by
Greenspan, Paul D
,
Fujimoto, Roger A
,
Marshall, Paul J
,
Raychaudhuri, Anil
,
Lipson, Kenneth E
,
Zhou, Huanghai
,
Doti, Robert A
,
Coppa, David E
,
Zhu, Lijuan
,
Pelletier, Roberta
,
Uziel-Fusi, Susan
,
Jackson, Robert H
,
Chin, Michael H
,
Kotyuk, Bernard L
,
Fitt, John J
Published in
Journal of medicinal chemistry
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N-aryl cinnamides : A novel class of rigid and highly potent leukotriene B4 receptor antagonists
by
GREENSPAN, P. D
,
MAIN, A. J
,
JACKSON, R. H
,
UZIEL-FUSI, S
,
BHAGWAT, S. S
,
BARSKY, L. I
,
DOTI, R. A
,
ENGLE, A. R
,
FREY, L. M
,
ZHOU, H
,
LIPSON, K. E
,
CHIN, M. H
Published in
Bioorganic & medicinal chemistry letters
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Carboxy-Substituted Cinnamides: A Novel Series of Potent, Orally Active LTB 4 Receptor Antagonists
by
Greenspan, Paul D.
,
Fujimoto, Roger A.
,
Marshall, Paul J.
,
Raychaudhuri, Anil
,
Lipson, Kenneth E.
,
Zhou, Huanghai
,
Doti, Robert A.
,
Coppa, David E.
,
Zhu, Lijuan
,
Pelletier, Roberta
,
Uziel-Fusi, Susan
,
Jackson, Robert H.
,
Chin, Michael H.
,
Kotyuk, Bernard L.
,
Fitt, John J.
Published in
Journal of medicinal chemistry
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N-aryl cinnamides: A novel class of rigid and highly potent leukotriene B 4 receptor antagonists
by
Greenspan, Paul D.
,
Main, Alan J.
,
Bhagwat, Shripad S.
,
Barsky, Lester I.
,
Doti, Robert A.
,
Engle, Alan R.
,
Frey, Lisa M.
,
Zhou, Huanghai
,
Lipson, Kenneth E.
,
Chin, Michael H.
,
Jackson, Robert H.
,
Uziel-Fusi, Susan
Published in
Bioorganic & medicinal chemistry letters
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Synthesis with HOCl: conversion of pulegone and isopulegol to menthofuran: preparation of 3,6-dimethyl-2,6-cycloheptadien-1-one from phorone
by
HEGDE, S. G
,
BECKWITH, D
,
DOTI, R
,
WOLINSKY, J
Published in
Journal of organic chemistry
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Synthesis with hypochlorous acid. Conversion to pulegone and isopulegol to menthofuran. Preparation of 3,6-dimethyl-2,6-cycloheptadien-1-one from phorone
by
Hegde, Shridhar G
,
Beckwith, David
,
Doti, Robert
,
Wolinsky, Joseph
Published in
Journal of organic chemistry
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