Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial by Lyttle, Mark D, Rainford, Naomi E A, Gamble, Carrol, Messahel, Shrouk, Humphreys, Amy, Hickey, Helen, Woolfall, Kerry, Roper, Louise, Noblet, Joanne, Lee, Elizabeth D, Tate, Paul, Iyer, Anand, Evans, Vicki, Appleton, Richard E, Hardwick, Susie, Messahel, Shrouk, Lee, Elizabeth D, Buchanan, Mark, Lewis, Lucy, Hughes, Sharon, Rogers, Louise, Hopkins, Juliet, Lyttle, Mark D, Fernandez, Daphin, Potter, Sarah, Lavigne-Smith, Holly R, Moulsdale, Phoebe, Ross, James, Ramsey, Natasha, Hacking, Jo, Mullen, Niall, Corrigan, Paul P, Prudhoe, Sarah, Faza, Hani, Robinson, Gisela, Sunley, Rachel C, Unsworth, Vanessa, Criddle, John, Sheedy, Alyce B, Anderson, Mark, Bell, Kathryn, Devine, Kirsty, Scott, Alex, Kumar, Ramesh, Armstrong, Sonia, Sutherland, Emer, Helyer, Sinead, Riozzi, Paul, Cotton, Hannah, Downes, Alice J, Mollard, Helen, Roland, Damian, Gough, Christopher, Finucane, Sonya, Bevan, Catherine, Ramsay, Rebecca, Walton, Emily, Maney, Julie-Ann, Dalzell, Elizabeth, Millar, Muriel, Howells, Rachel J, Appelboam, Andy, Mackle, Daisy, Small, Jennie, Neil, Ashleigh, Choudhery, Vince, MacLeod, Stewart, O'Neill, Thomas, Grahamslaw, Julia, Parikh, Ami, Skene, Imogen, Potier de la Morandiere, Katherine, Wilson, Jill L, Danziger, Donna, Burke, Derek, Ramlakhan, Shammi, Evans, Jayne, Morcombe, Julie, Gormley, Stuart, Barling, Jason M, Cathie, Katrina, Bayreuther, Jane, Ensom, Ruth, Iqbal, Yasser, Rounding, Sarah, Bell, Claire, McLellan, Shona, Nyirenda, Maggie, Crome, Laura, Williamson, Neil, Alcock, Anastasia, Edwards, Sara, Morgan, Jeff, Powell, Colin VE, Ramesh, Chaniyil A, Kamal-Uddin, Solomon, Linney, Mike, Vamvakiti, Katia, Floyd, Sharon, Hobden, Gill

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Seizure control via pH manipulation: a phase II double-blind randomised controlled trial of inhaled carbogen as adjunctive treatment of paediatric convulsive status epilepticus (Ca... by Forsyth, Rob, Allen, Maria, Bedson, Emma, Downes, Alice, Gough, Chris, Hartshorn, Stuart, Lawton, Kelly, Lyttle, Mark D, Messahel, Shrouk, Mullen, Niall, Raper, Joseph, Rosala-Harris, Anna, Taggart, Leigh, Urron, Jason, Walton, Emily, Gamble, Carrol

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1405 Neonates presenting to the paediatric emergency department and the effects of the COVID-19 pandemic by Tabib, Najwa, Pearson, Rachel, Downes, Alice

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Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury: The CRYOSTAT-2 Randomized Clinical Trial by Davenport, Ross, Curry, Nicola, Fox, Erin E, Thomas, Helen, Lucas, Joanne, Evans, Amy, Shanmugaranjan, Shaminie, Sharma, Rupa, Deary, Alison, Edwards, Antoinette, Green, Laura, Wade, Charles E, Benger, Jonathan R, Cotton, Bryan A, Stanworth, Simon J, Brohi, Karim

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Clinical Impact of Serious Respiratory Disease in Children Under the Age of 2 Years During the 2021-2022 Bronchiolitis Season in England, Scotland, and Ireland by Williams, Thomas C, Marlow, Robin, Hardelid, Pia, Lyttle, Mark D, Lewis, Kate M, Mpamhanga, Chengetai D, Cunningham, Steve, Roland, Damian

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Point-of-care testing in Paediatric settings in the UK and Ireland: a cross-sectional study by Pandey, Meenu, Lyttle, Mark D, Cathie, Katrina, Munro, Alasdair, Waterfield, Thomas, Roland, Damian

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VIDEO REVIEW by Downes, Alice

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The CIDA Variability Survey of Orion OB1. II. Demographics of the Young, Low-mass Stellar Populations by Briceño, César, Calvet, Nuria, Hernández, Jesús, Vivas, A. Katherina, Mateu, Cecilia, Downes, Juan José, Loerincs, Jaqueline, Pérez-Blanco, Alice, Berlind, Perry, Espaillat, Catherine, Allen, Lori, Hartmann, Lee, Mateo, Mario, Bailey III, John I.

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Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease by Douangamath, Alice, Fearon, Daren, Gehrtz, Paul, Krojer, Tobias, Lukacik, Petra, Owen, C. David, Resnick, Efrat, Strain-Damerell, Claire, Aimon, Anthony, Ábrányi-Balogh, Péter, Brandão-Neto, José, Carbery, Anna, Davison, Gemma, Dias, Alexandre, Downes, Thomas D., Dunnett, Louise, Fairhead, Michael, Firth, James D., Jones, S. Paul, Keeley, Aaron, Keserü, György M., Klein, Hanna F., Martin, Mathew P., Noble, Martin E. M., O’Brien, Peter, Powell, Ailsa, Reddi, Rambabu N., Skyner, Rachael, Snee, Matthew, Waring, Michael J., Wild, Conor, London, Nir, von Delft, Frank, Walsh, Martin A.

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Missense Mutations in a Retinal Pigment Epithelium Protein, Bestrophin-1, Cause Retinitis Pigmentosa by Davidson, Alice E., Millar, Ian D., Urquhart, Jill E., Burgess-Mullan, Rosemary, Shweikh, Yusrah, Parry, Neil, O'Sullivan, James, Maher, Geoffrey J., McKibbin, Martin, Downes, Susan M., Lotery, Andrew J., Jacobson, Samuel G., Brown, Peter D., Black, Graeme C.M., Manson, Forbes D.C.

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Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease by Watt, Stephen, Vasquez, Louella, Walter, Klaudia, Mann, Alice L., Kundu, Kousik, Chen, Lu, Sims, Ying, Ecker, Simone, Burden, Frances, Farrow, Samantha, Farr, Ben, Iotchkova, Valentina, Elding, Heather, Mead, Daniel, Tardaguila, Manuel, Ponstingl, Hannes, Richardson, David, Datta, Avik, Flicek, Paul, Clarke, Laura, Downes, Kate, Pastinen, Tomi, Fraser, Peter, Frontini, Mattia, Javierre, Biola-Maria, Spivakov, Mikhail, Soranzo, Nicole

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The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease by Astle, William J., Elding, Heather, Jiang, Tao, Allen, Dave, Ruklisa, Dace, Mann, Alice L., Mead, Daniel, Bouman, Heleen, Riveros-Mckay, Fernando, Kostadima, Myrto A., Lambourne, John J., Sivapalaratnam, Suthesh, Downes, Kate, Kundu, Kousik, Bomba, Lorenzo, Berentsen, Kim, Bradley, John R., Daugherty, Louise C., Delaneau, Olivier, Freson, Kathleen, Garner, Stephen F., Grassi, Luigi, Guerrero, Jose, Haimel, Matthias, Janssen-Megens, Eva M., Kaan, Anita, Kamat, Mihir, Kim, Bowon, Mandoli, Amit, Marchini, Jonathan, Martens, Joost H.A., Meacham, Stuart, Megy, Karyn, O’Connell, Jared, Petersen, Romina, Sharifi, Nilofar, Sheard, Simon M., Staley, James R., Tuna, Salih, van der Ent, Martijn, Walter, Klaudia, Wang, Shuang-Yin, Wheeler, Eleanor, Wilder, Steven P., Iotchkova, Valentina, Moore, Carmel, Sambrook, Jennifer, Stunnenberg, Hendrik G., Di Angelantonio, Emanuele, Kaptoge, Stephen, Kuijpers, Taco W., Carrillo-de-Santa-Pau, Enrique, Juan, David, Rico, Daniel, Valencia, Alfonso, Chen, Lu, Ge, Bing, Vasquez, Louella, Kwan, Tony, Garrido-Martín, Diego, Watt, Stephen, Yang, Ying, Guigo, Roderic, Beck, Stephan, Paul, Dirk S., Pastinen, Tomi, Bujold, David, Bourque, Guillaume, Frontini, Mattia, Danesh, John, Roberts, David J., Ouwehand, Willem H., Butterworth, Adam S., Soranzo, Nicole

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Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells by Chen, Lu, Ge, Bing, Casale, Francesco Paolo, Vasquez, Louella, Kwan, Tony, Garrido-Martín, Diego, Watt, Stephen, Yan, Ying, Kundu, Kousik, Ecker, Simone, Datta, Avik, Richardson, David, Burden, Frances, Mead, Daniel, Mann, Alice L., Fernandez, Jose Maria, Rowlston, Sophia, Wilder, Steven P., Farrow, Samantha, Shao, Xiaojian, Lambourne, John J., Redensek, Adriana, Albers, Cornelis A., Amstislavskiy, Vyacheslav, Ashford, Sofie, Berentsen, Kim, Bomba, Lorenzo, Bourque, Guillaume, Bujold, David, Busche, Stephan, Caron, Maxime, Chen, Shu-Huang, Cheung, Warren, Delaneau, Oliver, Dermitzakis, Emmanouil T., Elding, Heather, Colgiu, Irina, Bagger, Frederik O., Flicek, Paul, Habibi, Ehsan, Iotchkova, Valentina, Janssen-Megens, Eva, Kim, Bowon, Lehrach, Hans, Lowy, Ernesto, Mandoli, Amit, Matarese, Filomena, Maurano, Matthew T., Morris, John A., Pancaldi, Vera, Pourfarzad, Farzin, Rehnstrom, Karola, Rendon, Augusto, Risch, Thomas, Sharifi, Nilofar, Simon, Marie-Michelle, Sultan, Marc, Valencia, Alfonso, Walter, Klaudia, Wang, Shuang-Yin, Frontini, Mattia, Antonarakis, Stylianos E., Clarke, Laura, Yaspo, Marie-Laure, Beck, Stephan, Guigo, Roderic, Rico, Daniel, Martens, Joost H.A., Ouwehand, Willem H., Kuijpers, Taco W., Paul, Dirk S., Stunnenberg, Hendrik G., Stegle, Oliver, Downes, Kate, Pastinen, Tomi, Soranzo, Nicole

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Efficacy of nutritional interventions to lower circulating ceramides in young adults: FRUVEDomic pilot study by Mathews, Alice T., Famodu, Oluremi A., Olfert, Melissa D., Murray, Pamela J., Cuff, Christopher F., Downes, Marianne T., Haughey, Norman J., Colby, Sarah E., Chantler, Paul D., Olfert, I. Mark, McFadden, Joseph W.

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Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types by Ecker, Simone, Chen, Lu, Pancaldi, Vera, Bagger, Frederik O, Fernández, José María, Carrillo de Santa Pau, Enrique, Juan, David, Mann, Alice L, Watt, Stephen, Casale, Francesco Paolo, Sidiropoulos, Nikos, Rapin, Nicolas, Merkel, Angelika, Stunnenberg, Hendrik G, Stegle, Oliver, Frontini, Mattia, Downes, Kate, Pastinen, Tomi, Kuijpers, Taco W, Rico, Daniel, Valencia, Alfonso, Beck, Stephan, Soranzo, Nicole, Paul, Dirk S

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International, prospective cohort study comparing non-absorbable versus absorbable sutures for skin surgery: CANVAS service evaluation by Lee, Alice, Stanley, Guy H M, Wade, Ryckie G, Berwick, Daniele, Vinicombe, Victoria, Salence, Brogan K, Musbahi, Esra, De Poli, Anderson R C S, Savu, Mihaela, Batchelor, Jonathan M, Abbott, Rachel A, Gardiner, Matthew D, Wernham, Aaron, Veitch, David

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The CIDA Variability Survey of Orion OB1. II. Demographics of the Young, Low-mass Stellar Populations Based on observations obtained at the Llano del Hato National Astronomical Obs... by Briceño, César, Calvet, Nuria, Hernández, Jesús, Vivas, A. Katherina, Mateu, Cecilia, Downes, Juan José, Loerincs, Jaqueline, Pérez-Blanco, Alice, Berlind, Perry, Espaillat, Catherine, Allen, Lori, Hartmann, Lee, Mateo, Mario, Bailey III, John I.

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Personalised Risk Prediction in Hereditary Breast and Ovarian Cancer: A Protocol for a Multi-Centre Randomised Controlled Trial by Archer, Stephanie, Fennell, Nichola, Colvin, Ellen, Laquindanum, Rozelle, Mills, Meredith, Dennis, Romy, Stutzin Donoso, Francisca, Gold, Rochelle, Fan, Alice, Downes, Kate, Ford, James, Antoniou, Antonis C, Kurian, Allison W, Evans, D Gareth, Tischkowitz, Marc

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Fruit and Vegetable Intervention Lowers Circulating Ceramide Levels and Improves Estimated Insulin Sensitivity in Young Adults at Risk of Developing Metabolic Syndrome: A FRUVEDomi... by Mathews, Alice T., Famodu, Oluremi A., Olfert, Melissa D., Murray, Pamela J., Cuff, Chris F., Downes, Marianne T., Haughey, Norman J., Colby, Sarah E., Olfert, I. Mark, McFadden, Joseph W.

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Association of Center-Specific Patient Volumes and Early Respiratory Management Practices with Death and Bronchopulmonary Dysplasia in Preterm Infants by Spotswood, Naomi, Orsini, Francesca, Dargaville, Peter, Marshall, Peter, Schmidt, Peter, Craven, Paul, de Waal, Koert, Simmer, Karen, Gill, Andy, Pillow, Jane, Stack, Jacqueline, Birch, Pita, Cooke, Lucy, Casalaz, Dan, Holberton, Jim, Stewart, Alice, Downe, Lyn, Stewart, Michael, Berry, Andrew, Hunt, Rod, Kilburn, Charles, De Paoli, Tony, Lui, Kei, Paradisis, Mary, Rieger, Ingrid, Koorts, Pieter, Kuschel, Carl, Doyle, Lex, Numa, Andrew, Carlisle, Hazel, Badawi, Nadia, Jorgensen, Christine, Koh, Guan, Davis, Jonathan, Luig, Melissa, Andersen, Chad, Lynn, Adrienne, Darlow, Brian, Edmonds, Liza, Mildenhall, Lindsay, Buksh, Mariam, Battin, Malcolm, Bourchier, David, Richardson, Vaughan, Chambers, Georgina, Rajadurai, Victor Samuel, Bajuk, Barbara, van den Boom, Jutta

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