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Search Results - Earr, Timothy K
Search Results - Earr, Timothy K
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Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients
by
Bhalla, Akhil
,
Ravi, Ritesh
,
Fang, Meng
,
Arguello, Annie
,
Davis, Sonnet S
,
Chiu, Chi-Lu
,
Blumenfeld, Jessica R
,
Nguyen, Hoang N
,
Earr, Timothy K
,
Wang, Junhua
,
Astarita, Giuseppe
,
Zhu, Yuda
,
Fiore, Damian
,
Scearce-Levie, Kimberly
,
Diaz, Dolores
,
Cahan, Heather
,
Troyer, Matthew D
,
Harris, Jeffrey M
,
Escolar, Maria L
Published in
International journal of molecular sciences
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TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge
by
Nugent, Alicia A.
,
Lin, Karin
,
van Lengerich, Bettina
,
Lianoglou, Steve
,
Przybyla, Laralynne
,
Davis, Sonnet S.
,
Llapashtica, Ceyda
,
Wang, Junhua
,
Kim, Do Jin
,
Xia, Dan
,
Lucas, Anthony
,
Baskaran, Sulochanadevi
,
Haddick, Patrick C.G.
,
Lenser, Melina
,
Earr, Timothy K.
,
Shi, Ju
,
Dugas, Jason C.
,
Andreone, Benjamin J.
,
Logan, Todd
,
Solanoy, Hilda O.
,
Chen, Hang
,
Srivastava, Ankita
,
Poda, Suresh B.
,
Sanchez, Pascal E.
,
Watts, Ryan J.
,
Sandmann, Thomas
,
Astarita, Giuseppe
,
Lewcock, Joseph W.
,
Monroe, Kathryn M.
,
Di Paolo, Gilbert
Published in
Neuron (Cambridge, Mass.)
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Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
by
Logan, Todd
,
Simon, Matthew J.
,
Rana, Anil
,
Cherf, Gerald M.
,
Srivastava, Ankita
,
Davis, Sonnet S.
,
Low, Ray Lieh Yoon
,
Chiu, Chi-Lu
,
Fang, Meng
,
Huang, Fen
,
Bhalla, Akhil
,
Llapashtica, Ceyda
,
Prorok, Rachel
,
Pizzo, Michelle E.
,
Calvert, Meredith E.K.
,
Sun, Elizabeth W.
,
Hsiao-Nakamoto, Jennifer
,
Rajendra, Yashas
,
Lexa, Katrina W.
,
Srivastava, Devendra B.
,
van Lengerich, Bettina
,
Wang, Junhua
,
Robles-Colmenares, Yaneth
,
Kim, Do Jin
,
Duque, Joseph
,
Lenser, Melina
,
Earr, Timothy K.
,
Nguyen, Hoang
,
Chau, Roni
,
Tsogtbaatar, Buyankhishig
,
Ravi, Ritesh
,
Skuja, Lukas L.
,
Solanoy, Hilda
,
Rosen, Howard J.
,
Boeve, Bradley F.
,
Boxer, Adam L.
,
Heuer, Hilary W.
,
Dennis, Mark S.
,
Kariolis, Mihalis S.
,
Monroe, Kathryn M.
,
Przybyla, Laralynne
,
Sanchez, Pascal E.
,
Meisner, Rene
,
Diaz, Dolores
,
Henne, Kirk R.
,
Watts, Ryan J.
,
Henry, Anastasia G.
,
Gunasekaran, Kannan
,
Astarita, Giuseppe
,
Suh, Jung H.
,
Lewcock, Joseph W.
,
DeVos, Sarah L.
,
Di Paolo, Gilbert
Published in
Cell
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Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia
by
Xia, Dan
,
Lianoglou, Steve
,
Sandmann, Thomas
,
Calvert, Meredith
,
Suh, Jung H
,
Thomsen, Elliot
,
Dugas, Jason
,
Pizzo, Michelle E
,
DeVos, Sarah L
,
Earr, Timothy K
,
Lin, Chia-Ching
,
Davis, Sonnet
,
Ha, Connie
,
Leung, Amy Wing-Sze
,
Nguyen, Hoang
,
Chau, Roni
,
Yulyaningsih, Ernie
,
Lopez, Isabel
,
Solanoy, Hilda
,
Masoud, Shababa T
,
Liang, Chun-Chi
,
Lin, Karin
,
Astarita, Giuseppe
,
Khoury, Nathalie
,
Zuchero, Joy Yu
,
Thorne, Robert G
,
Shen, Kevin
,
Miller, Stephanie
,
Palop, Jorge J
,
Garceau, Dylan
,
Sasner, Michael
,
Whitesell, Jennifer D
,
Harris, Julie A
,
Hummel, Selina
,
Gnörich, Johannes
,
Wind, Karin
,
Kunze, Lea
,
Zatcepin, Artem
,
Brendel, Matthias
,
Willem, Michael
,
Haass, Christian
,
Barnett, Daniel
,
Zimmer, Till S
,
Orr, Anna G
,
Scearce-Levie, Kimberly
,
Lewcock, Joseph W
,
Di Paolo, Gilbert
,
Sanchez, Pascal E
Published in
Molecular neurodegeneration
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BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats
by
Weber, Martin
,
Wu, Tiffany
,
Meilandt, William J.
,
Dominguez, Sara L.
,
Solanoy, Hilda O.
,
Maloney, Janice A.
,
Ngu, Hai
,
Baca, Miriam
,
Kung, Chung
,
Lima, Lisa
,
Earr, Timothy K.
,
Fleck, Daniel
,
Shields, Shannon D.
,
Forrest, William F.
,
Foreman, Oded
,
Warming, Søren
,
Watts, Ryan J.
,
Scearce-Levie, Kimberly
Published in
Scientific reports
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CD98hc is a target for brain delivery of biotherapeutics
by
Chew, Kylie S.
,
Wells, Robert C.
,
Moshkforoush, Arash
,
Chan, Darren
,
Lechtenberg, Kendra J.
,
Tran, Hai L.
,
Chow, Johann
,
Kim, Do Jin
,
Robles-Colmenares, Yaneth
,
Srivastava, Devendra B.
,
Tong, Raymond K.
,
Tong, Mabel
,
Xa, Kaitlin
,
Yang, Alexander
,
Zhou, Yinhan
,
Akkapeddi, Padma
,
Annamalai, Lakshman
,
Bajc, Kaja
,
Blanchette, Marie
,
Cherf, Gerald Maxwell
,
Earr, Timothy K.
,
Gill, Audrey
,
Huynh, David
,
Joy, David
,
Knight, Kristen N.
,
Lac, Diana
,
Leung, Amy Wing-Sze
,
Lexa, Katrina W.
,
Liau, Nicholas P. D.
,
Becerra, Isabel
,
Malfavon, Mario
,
McInnes, Joseph
,
Nguyen, Hoang N.
,
Lozano, Edwin I.
,
Pizzo, Michelle E.
,
Roche, Elysia
,
Sacayon, Patricia
,
Calvert, Meredith E. K.
,
Daneman, Richard
,
Dennis, Mark S.
,
Duque, Joseph
,
Gadkar, Kapil
,
Lewcock, Joseph W.
,
Mahon, Cathal S.
,
Meisner, René
,
Solanoy, Hilda
,
Thorne, Robert G.
,
Watts, Ryan J.
,
Zuchero, Y. Joy Yu
,
Kariolis, Mihalis S.
Published in
Nature communications
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Author Correction: CD98hc is a target for brain delivery of biotherapeutics
by
Chew, Kylie S.
,
Wells, Robert C.
,
Moshkforoush, Arash
,
Chan, Darren
,
Lechtenberg, Kendra J.
,
Tran, Hai L.
,
Chow, Johann
,
Kim, Do Jin
,
Robles-Colmenares, Yaneth
,
Srivastava, Devendra B.
,
Tong, Raymond K.
,
Tong, Mabel
,
Xa, Kaitlin
,
Yang, Alexander
,
Zhou, Yinhan
,
Akkapeddi, Padma
,
Annamalai, Lakshman
,
Bajc, Kaja
,
Blanchette, Marie
,
Cherf, Gerald Maxwell
,
Earr, Timothy K.
,
Gill, Audrey
,
Huynh, David
,
Joy, David
,
Knight, Kristen N.
,
Lac, Diana
,
Leung, Amy Wing-Sze
,
Lexa, Katrina W.
,
Liau, Nicholas P. D.
,
Becerra, Isabel
,
Malfavon, Mario
,
McInnes, Joseph
,
Nguyen, Hoang N.
,
Lozano, Edwin I.
,
Pizzo, Michelle E.
,
Roche, Elysia
,
Sacayon, Patricia
,
Calvert, Meredith E. K.
,
Daneman, Richard
,
Dennis, Mark S.
,
Duque, Joseph
,
Gadkar, Kapil
,
Lewcock, Joseph W.
,
Mahon, Cathal S.
,
Meisner, René
,
Solanoy, Hilda
,
Thorne, Robert G.
,
Watts, Ryan J.
,
Zuchero, Y. Joy Yu
,
Kariolis, Mihalis S.
Published in
Nature communications
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Evaluation of fluid biomarkers reveals lysosome dysfunction and neurodegeneration in neuronopathic MPS II patients
by
Bhalla, Akhil
,
Ravi, Ritesh
,
Fang, Meng
,
Arguello, Annie
,
Davis, Sonnet S.
,
Chiu, Chi-Lu
,
Blumenfeld, Jessica R.
,
Nguyen, Hoang N.
,
Earr, Timothy K.
,
Wang, Junhua
,
Astarita, Giuseppe
,
Zhu, Yuda
,
Fiore, Damian
,
Scearce-Levie, Kimberly
,
Diaz, Dolores
,
Cahan, Heather
,
Troyer, Matthew D.
,
Harris, Jeffrey M.
,
Escolar, Maria L.
Published in
Molecular genetics and metabolism
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Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
by
Ullman, Julie C
,
Arguello, Annie
,
Getz, Jennifer A
,
Bhalla, Akhil
,
Mahon, Cathal S
,
Wang, Junhua
,
Giese, Tina
,
Bedard, Catherine
,
Kim, Do Jin
,
Blumenfeld, Jessica R
,
Liang, Nicholas
,
Ravi, Ritesh
,
Nugent, Alicia A
,
Davis, Sonnet S
,
Ha, Connie
,
Duque, Joseph
,
Tran, Hai L
,
Wells, Robert C
,
Lianoglou, Steve
,
Daryani, Vinay M
,
Kwan, Wanda
,
Solanoy, Hilda
,
Nguyen, Hoang
,
Earr, Timothy
,
Dugas, Jason C
,
Tuck, Michael D
,
Harvey, Jennifer L
,
Reyzer, Michelle L
,
Caprioli, Richard M
,
Hall, Sejal
,
Poda, Suresh
,
Sanchez, Pascal E
,
Dennis, Mark S
,
Gunasekaran, Kannan
,
Srivastava, Ankita
,
Sandmann, Thomas
,
Henne, Kirk R
,
Thorne, Robert G
,
Di Paolo, Gilbert
,
Astarita, Giuseppe
,
Diaz, Dolores
,
Silverman, Adam P
,
Watts, Ryan J
,
Sweeney, Zachary K
,
Kariolis, Mihalis S
,
Henry, Anastasia G
Published in
Science translational medicine
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Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic...
by
Craig, Robert A.
,
Fox, Brian M.
,
Hu, Cheng
,
Lexa, Katrina W.
,
Osipov, Maksim
,
Thottumkara, Arun P.
,
Larhammar, Martin
,
Miyamoto, Takashi
,
Rana, Anil
,
Kane, Lesley A.
,
Yulyaningsih, Ernie
,
Solanoy, Hilda
,
Nguyen, Hoang
,
Chau, Roni
,
Earr, Timothy
,
Kajiwara, Yuji
,
Fleck, Daniel
,
Lucas, Anthony
,
Haddick, Patrick C. G.
,
Takahashi, Ryan H.
,
Tong, Vincent
,
Wang, Jing
,
Canet, Mark J.
,
Poda, Suresh B.
,
Scearce-Levie, Kimberly
,
Srivastava, Ankita
,
Sweeney, Zachary K.
,
Xu, Musheng
,
Zhang, Rui
,
He, Jianrong
,
Lei, Yanan
,
Zhuo, Zheng
,
de Vicente, Javier
Published in
Journal of medicinal chemistry
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