ABT-165, a Dual Variable Domain Immunoglobulin (DVD-Ig) Targeting DLL4 and VEGF, Demonstrates Superior Efficacy and Favorable Safety Profiles in Preclinical Models by Li, Yingchun, Hickson, Jonathan A, Ambrosi, Dominic J, Haasch, Deanna L, Foster-Duke, Kelly D, Eaton, Lucia J, DiGiammarino, Enrico L, Panchal, Sanjay C, Jiang, Fang, Mudd, Sarah R, Zhang, Catherine, Akella, Surekha S, Gao, Wenqing, Ralston, Sherry L, Naumovski, Louie, Gu, Jijie, Morgan-Lappe, Susan E

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Transmembrane TNF-dependent uptake of anti-TNF antibodies by Deora, Arun, Hegde, Subramanya, Lee, Jacqueline, Choi, Chee-Ho, Chang, Qing, Lee, Cheryl, Eaton, Lucia, Tang, Hua, Wang, Dongdong, Lee, David, Michalak, Mark, Tomlinson, Medha, Tao, Qingfeng, Gaur, Nidhi, Harvey, Bohdan, McLoughlin, Shaun, Labkovsky, Boris, Ghayur, Tariq

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Abstract 867: ABT-165 is a first-in-class therapeutic Dual Variable Domain Immunoglobulin (DVD-IgTM) that targets DLL4 and VEGF for the treatment of cancer by Li, Yingchun, Hickson, Jonathan, Ambrosi, Dominic, Haasch, Deanna, Foster-Duke, Kelly, Eaton, Lucia, Jiang, Fang, Akella, Surekha, Gao, Wenqing, Ralston, Sherry, Gu, Jijie, Morgan-Lappe, Susan

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Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of... by Ding, Kun, Eaton, Lucia, Bowley, Diana, Rieser, Matthew, Chang, Qing, Harris, Maria C, Clabbers, Anca, Dong, Feng, Shen, Jikui, Hackett, Sean F, Touw, Debra S, Bixby, Jacqueline, Zhong, Suju, Benatuil, Lorenzo, Bose, Sahana, Grinnell, Christine, Preston, Gregory M, Iyer, Ramesh, Sadhukhan, Ramkrishna, Marchie, Susan, Overmeyer, Gary, Ghayur, Tariq, van Riet, Deborah A, Tang, Shibo, Campochario, Peter A, Gu, Jijie

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Engineering elastic properties into an anti-TNFα monoclonal antibody by Sadhukhan, Ramkrishna, Brown, Nathan, Ouellette, David, Banach, David, Filoti, Dana I., Winarta, David, Raghavendra, Reema, Sousa, Silvino, Darcy, Anhdao, Alessandri, Leslie, Ivanov, Alexander, Bose, Sahana, Eaton, Lucia, Preston, Gregory, Freeman, Jeremy, Correia, Ivan

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Transmembrane TNF-dependent uptake of anti-TNF antibodies by Deora, Arun, Hegde, Subramanya, Lee, Jacqueline, Choi, Chee-Ho, Chang, Qing, Lee, Cheryl, Eaton, Lucia, Tang, Hua, Wang, Dongdong, Lee, David, Michalak, Mark, Tomlinson, Medha, Tao, Qingfeng, Gaur, Nidhi, Harvey, Bohdan, McLoughlin, Shaun, Labkovsky, Boris, Ghayur, Tariq

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Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of... by Ding, Kun, Eaton, Lucia, Bowley, Diana, Rieser, Matthew, Chang, Qing, Harris, Maria C., Clabbers, Anca, Dong, Feng, Shen, Jikui, Hackett, Sean F., Touw, Debra S., Bixby, Jacqueline, Zhong, Suju, Benatuil, Lorenzo, Bose, Sahana, Grinnell, Christine, Preston, Gregory M., Iyer, Ramesh, Sadhukhan, Ramkrishna, Marchie, Susan, Overmeyer, Gary, Ghayur, Tariq, van Riet, Deborah A., Tang, Shibo, Campochario, Peter A., Gu, Jijie

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Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study by Carlson, Christopher S, Matise, Tara C, North, Kari E, Haiman, Christopher A, Fesinmeyer, Megan D, Buyske, Steven, Schumacher, Fredrick R, Peters, Ulrike, Franceschini, Nora, Ritchie, Marylyn D, Duggan, David J, Spencer, Kylee L, Dumitrescu, Logan, Eaton, Charles B, Thomas, Fridtjof, Young, Alicia, Carty, Cara, Heiss, Gerardo, Le Marchand, Loic, Crawford, Dana C, Hindorff, Lucia A, Kooperberg, Charles L

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Vaccination with embryonic stem cells protects against lung cancer: is a broad-spectrum prophylactic vaccine against cancer possible? by Yaddanapudi, Kavitha, Mitchell, Robert A, Putty, Kalyani, Willer, Sharon, Sharma, Rajesh K, Yan, Jun, Bodduluri, Haribabu, Eaton, John W

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Echocardiographic Strain Analysis for the Early Detection of Left Ventricular Systolic/Diastolic Dysfunction and Dyssynchrony in a Mouse Model of Physiological Aging by de Lucia, Claudio, Wallner, Markus, Eaton, Deborah M, Zhao, Huaqing, Houser, Steven R, Koch, Walter J

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Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study by Dumitrescu, Logan, Carty, Cara L, Taylor, Kira, Schumacher, Fredrick R, Hindorff, Lucia A, Ambite, José L, Anderson, Garnet, Best, Lyle G, Brown-Gentry, Kristin, Bůžková, Petra, Carlson, Christopher S, Cochran, Barbara, Cole, Shelley A, Devereux, Richard B, Duggan, Dave, Eaton, Charles B, Fornage, Myriam, Franceschini, Nora, Haessler, Jeff, Howard, Barbara V, Johnson, Karen C, Laston, Sandra, Kolonel, Laurence N, Lee, Elisa T, MacCluer, Jean W, Manolio, Teri A, Pendergrass, Sarah A, Quibrera, Miguel, Shohet, Ralph V, Wilkens, Lynne R, Haiman, Christopher A, Le Marchand, Loïc, Buyske, Steven, Kooperberg, Charles, North, Kari E, Crawford, Dana C

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Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe by Flaxman, Seth, Mishra, Swapnil, Gandy, Axel, Unwin, H. Juliette T., Mellan, Thomas A., Coupland, Helen, Whittaker, Charles, Zhu, Harrison, Berah, Tresnia, Eaton, Jeffrey W., Monod, Mélodie, Ghani, Azra C., Donnelly, Christl A., Riley, Steven, Vollmer, Michaela A. C., Ferguson, Neil M., Okell, Lucy C., Bhatt, Samir

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Engineered anti-inflammatory peptides inspired by mapping an evasin–chemokine interaction by Darlot, Benoit, Eaton, James R.O., Geis-Asteggiante, Lucia, Yakala, Gopala K., Karuppanan, Kalimuthu, Davies, Graham, Robinson, Carol V., Kawamura, Akane, Bhattacharya, Shoumo

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The N-terminal domain of a tick evasin is critical for chemokine binding and neutralization and confers specific binding activity to other evasins by Eaton, James R.O., Alenazi, Yara, Singh, Kamayani, Davies, Graham, Geis-Asteggiante, Lucia, Kessler, Benedikt, Robinson, Carol V., Kawamura, Akane, Bhattacharya, Shoumo

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Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study by Buyske, Steven, Wu, Ying, Carty, Cara L, Cheng, Iona, Assimes, Themistocles L, Dumitrescu, Logan, Hindorff, Lucia A, Mitchell, Sabrina, Ambite, Jose Luis, Boerwinkle, Eric, Buzkova, Petra, Carlson, Chris S, Cochran, Barbara, Duggan, David, Eaton, Charles B, Fesinmeyer, Megan D, Franceschini, Nora, Haessler, Jeffrey, Jenny, Nancy, Kang, Hyun Min, Kooperberg, Charles, Lin, Yi, Le Marchand, Loic, Matise, Tara C, Robinson, Jennifer G, Rodriguez, Carlos, Schumacher, Fredrick R, Voight, Benjamin F, Young, Alicia, Manolio, Teri A, Mohlke, Karen L, Haiman, Christopher A, Peters, Ulrike, Crawford, Dana C, North, Kari E

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Colombian Adolescents’ Perceptions of Violence and Opportunities for Safe Spaces Across Community Settings by De la Vega-Taboada, Eduardo, Rodriguez, Ana Lucia, Barton, Alexa, Stephens, Dionne P., Cano, Miguel, Eaton, Asia, Frazier, Stacy, Rodriguez, Augusto, Cortecero, Adolfo

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Adolescent Social Networks and Physical Intimate Partner Violence Among Colombian Rural Adolescents by Rodríguez de la Rosa, Ana Lucia, Stephens, Dionne, Montes, Felipe, Sarmiento, Olga L., De la Vega-Taboada, Eduardo L., Eaton, Asia, Schreiber Compo, Nadja, Madhivanan, Purnima

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Enhancing Access to Early Intervention by Including Parent Navigators With Lived Experience in a Pediatric Medical Home by Mirzaian, Christine B., Solomon, Olga, Setaghiyan, Helen, Hudson, Sharon, Goldfarb, Fran, Eaton, Guadalupe Lorena, Vasquez, Rita, Babb, Lucia, Yin, Larry

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Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained by Wu, Ying, Waite, Lindsay L, Jackson, Anne U, Sheu, Wayne H-H, Buyske, Steven, Absher, Devin, Arnett, Donna K, Boerwinkle, Eric, Bonnycastle, Lori L, Carty, Cara L, Cheng, Iona, Cochran, Barbara, Croteau-Chonka, Damien C, Dumitrescu, Logan, Eaton, Charles B, Franceschini, Nora, Guo, Xiuqing, Henderson, Brian E, Hindorff, Lucia A, Kim, Eric, Kinnunen, Leena, Komulainen, Pirjo, Lee, Wen-Jane, Le Marchand, Loic, Lin, Yi, Lindström, Jaana, Lingaas-Holmen, Oddgeir, Mitchell, Sabrina L, Narisu, Narisu, Robinson, Jennifer G, Schumacher, Fred, Stančáková, Alena, Sundvall, Jouko, Sung, Yun-Ju, Swift, Amy J, Wang, Wen-Chang, Wilkens, Lynne, Wilsgaard, Tom, Young, Alicia M, Adair, Linda S, Ballantyne, Christie M, Bůžková, Petra, Chakravarti, Aravinda, Collins, Francis S, Duggan, David, Feranil, Alan B, Ho, Low-Tone, Hung, Yi-Jen, Hunt, Steven C, Hveem, Kristian, Juang, Jyh-Ming J, Kesäniemi, Antero Y, Kuusisto, Johanna, Laakso, Markku, Lakka, Timo A, Lee, I-Te, Leppert, Mark F, Matise, Tara C, Moilanen, Leena, Njølstad, Inger, Peters, Ulrike, Quertermous, Thomas, Rauramaa, Rainer, Rotter, Jerome I, Saramies, Jouko, Tuomilehto, Jaakko, Uusitupa, Matti, Wang, Tzung-Dau, Boehnke, Michael, Haiman, Christopher A, Chen, Yii-Der I, Kooperberg, Charles, Assimes, Themistocles L, Crawford, Dana C, Hsiung, Chao A, North, Kari E, Mohlke, Karen L

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Oxyfunctionalization of Non-Natural Targets by Dioxiranes. 6. On the Selective Hydroxylation of Cubane by Annese, Cosimo, D’Accolti, Lucia, Fusco, Caterina, Gandolfi, Remo, Eaton, Philip E, Curci, Ruggero

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