Accelerating functional gene discovery in osteoarthritis by Butterfield, Natalie C., Curry, Katherine F., Steinberg, Julia, Dewhurst, Hannah, Komla-Ebri, Davide, Mannan, Naila S., Adoum, Anne-Tounsia, Leitch, Victoria D., Logan, John G., Waung, Julian A., Ghirardello, Elena, Southam, Lorraine, Youlten, Scott E., Wilkinson, J. Mark, McAninch, Elizabeth A., Vancollie, Valerie E., Kussy, Fiona, White, Jacqueline K., Lelliott, Christopher J., Adams, David J., Jacques, Richard, Bianco, Antonio C., Boyde, Alan, Zeggini, Eleftheria, Croucher, Peter I., Williams, Graham R., Bassett, J. H. Duncan

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The empirical power of rare variant association methods: results from sanger sequencing in 1,998 individuals by Ladouceur, Martin, Dastani, Zari, Aulchenko, Yurii S, Greenwood, Celia M T, Richards, J Brent

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Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls by Liu, Li, Sabo, Aniko, Neale, Benjamin M, Nagaswamy, Uma, Stevens, Christine, Lim, Elaine, Bodea, Corneliu A, Muzny, Donna, Reid, Jeffrey G, Banks, Eric, Coon, Hillary, Depristo, Mark, Dinh, Huyen, Fennel, Tim, Flannick, Jason, Gabriel, Stacey, Garimella, Kiran, Gross, Shannon, Hawes, Alicia, Lewis, Lora, Makarov, Vladimir, Maguire, Jared, Newsham, Irene, Poplin, Ryan, Ripke, Stephan, Shakir, Khalid, Samocha, Kaitlin E, Wu, Yuanqing, Boerwinkle, Eric, Buxbaum, Joseph D, Cook, Jr, Edwin H, Devlin, Bernie, Schellenberg, Gerard D, Sutcliffe, James S, Daly, Mark J, Gibbs, Richard A, Roeder, Kathryn

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Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia by Hackinger, Sophie, Prins, Bram, Mamakou, Vasiliki, Zengini, Eleni, Marouli, Eirini, Brčić, Luka, Serafetinidis, Ioannis, Lamnissou, Klea, Kontaxakis, Vassilis, Dedoussis, George, Gonidakis, Fragiskos, Thanopoulou, Anastasia, Tentolouris, Nikolaos, Tsezou, Aspasia, Zeggini, Eleftheria

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Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations by Xue, Yali, Mezzavilla, Massimo, Haber, Marc, McCarthy, Shane, Chen, Yuan, Narasimhan, Vagheesh, Gilly, Arthur, Ayub, Qasim, Colonna, Vincenza, Southam, Lorraine, Finan, Christopher, Massaia, Andrea, Chheda, Himanshu, Palta, Priit, Ritchie, Graham, Asimit, Jennifer, Dedoussis, George, Gasparini, Paolo, Palotie, Aarno, Ripatti, Samuli, Soranzo, Nicole, Toniolo, Daniela, Wilson, James F., Durbin, Richard, Tyler-Smith, Chris, Zeggini, Eleftheria

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Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood by Burkhardt, Ralph, Kirsten, Holger, Beutner, Frank, Holdt, Lesca M, Gross, Arnd, Teren, Andrej, Tönjes, Anke, Becker, Susen, Krohn, Knut, Kovacs, Peter, Stumvoll, Michael, Teupser, Daniel, Thiery, Joachim, Ceglarek, Uta, Scholz, Markus

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Multi-trait discovery and fine-mapping of lipid loci in 125,000 individuals of African ancestry by Kamiza, Abram Bunya, Touré, Sounkou M., Zhou, Feng, Soremekun, Opeyemi, Cissé, Cheickna, Wélé, Mamadou, Touré, Aboubacrine M., Nashiru, Oyekanmi, Corpas, Manuel, Nyirenda, Moffat, Crampin, Amelia, Shaffer, Jeffrey, Doumbia, Seydou, Zeggini, Eleftheria, Morris, Andrew P., Asimit, Jennifer L., Chikowore, Tinashe, Fatumo, Segun

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Estimating Genome-Wide Significance for Whole-Genome Sequencing Studies by Xu, ChangJiang, Tachmazidou, Ioanna, Walter, Klaudia, Ciampi, Antonio, Zeggini, Eleftheria, Greenwood, Celia M. T.

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Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis by Steinberg, Julia, Ritchie, Graham R. S., Roumeliotis, Theodoros I., Jayasuriya, Raveen L., Clark, Matthew J., Brooks, Roger A., Binch, Abbie L. A., Shah, Karan M., Coyle, Rachael, Pardo, Mercedes, Le Maitre, Christine L., Ramos, Yolande F. M., Nelissen, Rob G. H. H., Meulenbelt, Ingrid, McCaskie, Andrew W., Choudhary, Jyoti S., Wilkinson, J. Mark, Zeggini, Eleftheria

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ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls by Hendricks, Audrey E, Billups, Stephen C, Pike, Hamish N C, Farooqi, I Sadaf, Zeggini, Eleftheria, Santorico, Stephanie A, Barroso, Inês, Dupuis, Josée

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Identification of rare causal variants in sequence-based studies: methods and applications to VPS13B, a gene involved in Cohen syndrome and autism by Ionita-Laza, Iuliana, Capanu, Marinela, De Rubeis, Silvia, McCallum, Kenneth, Buxbaum, Joseph D

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Synthetic associations are unlikely to account for many common disease genome-wide association signals by Anderson, Carl A, Soranzo, Nicole, Zeggini, Eleftheria, Barrett, Jeffrey C

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Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders by Andersen, Mette Korre, Jørsboe, Emil, Sandholt, Camilla Helene, Grarup, Niels, Jørgensen, Marit Eika, Færgeman, Nils Joakim, Bjerregaard, Peter, Pedersen, Oluf, Moltke, Ida, Hansen, Torben, Albrechtsen, Anders

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Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin by Tönjes, Anke, Scholz, Markus, Breitfeld, Jana, Marzi, Carola, Grallert, Harald, Gross, Arnd, Ladenvall, Claes, Schleinitz, Dorit, Krause, Kerstin, Kirsten, Holger, Laurila, Esa, Kriebel, Jennifer, Thorand, Barbara, Rathmann, Wolfgang, Groop, Leif, Prokopenko, Inga, Isomaa, Bo, Beutner, Frank, Kratzsch, Jürgen, Thiery, Joachim, Fasshauer, Mathias, Klöting, Nora, Gieger, Christian, Blüher, Matthias, Stumvoll, Michael, Kovacs, Peter

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Genome-wide meta-analysis of 92 cardiometabolic protein serum levels by Gilly, Arthur, Park, Young-Chan, Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Zeggini, Eleftheria

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Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations by Kuchenbaecker, Karoline, Gilly, Arthur, Suveges, Daniel, Southam, Lorraine, Giannakopoulou, Olga, Kilian, Britt, Tsafantakis, Emmanouil, Karaleftheri, Maria, Farmaki, Aliki-Eleni, Gurdasani, Deepti, Kundu, Kousik, Sandhu, Manjinder S., Danesh, John, Butterworth, Adam, Barroso, Inês, Dedoussis, George, Zeggini, Eleftheria

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Rare variant association analysis methods for complex traits by Asimit, Jennifer, Zeggini, Eleftheria

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024 - INSIGHTS INTO THE GENOMIC AETIOLOGY OF OSTEOARTHRITIS: GENOME-WIDE ASSOCIATION STUDY META-ANALYSIS ACROSS 1,962,069 INDIVIDUALS by Hatzikotoulas, Konstantinos, Zeggini, Eleftheria

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INSIGHTS INTO THE GENOMIC AETIOLOGY OF OSTEOARTHRITIS: GENOME-WIDE ASSOCIATION STUDY META-ANALYSIS ACROSS 1,962,069 INDIVIDUALS by Hatzikotoulas, Konstantinos, Zeggini, Eleftheria

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Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits by Gilly, Arthur, Suveges, Daniel, Kuchenbaecker, Karoline, Pollard, Martin, Southam, Lorraine, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Bjornland, Thea, Waples, Ryan, Appel, Emil V. R., Casalone, Elisabetta, Melloni, Giorgio, Kilian, Britt, Rayner, Nigel W., Ntalla, Ioanna, Kundu, Kousik, Walter, Klaudia, Danesh, John, Butterworth, Adam, Barroso, Inês, Tsafantakis, Emmanouil, Dedoussis, George, Moltke, Ida, Zeggini, Eleftheria

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