Real world evidence (RWE) - a disruptive innovation or the quiet evolution of medical evidence generation? [version 1; peer review: 2 approved] by Khosla, Sajan, White, Robert, Medina, Jesús, Ouwens, Mario, Emmas, Cathy, Koder, Tim, Male, Gary, Leonard, Sandra

Get full text

Anifrolumab Study for Treatment Effectiveness in the Real World (ASTER) among patients with systemic lupus erythematosus: protocol for an international observational effectiveness... by Mosca, Marta, Emmas, Cathy, Nekeman-Nan, Cassandra, Stirnadel-Farrant, Heide, Chen, Samuel, Carty, Lucy, Waratani, Miina, Seo, Caroline, Chen, Stephanie, Sorrentino, Alessandro

Get full text

Characteristics and Symptom Severity of Patients Reporting Systemic Lupus Erythematosus in the PatientsLikeMe Online Health Community: A Retrospective Observational Study by Nyman, Elisabeth, Vaughan, Timothy, Desta, Barnabas, Wang, Xia, Barut, Volkan, Emmas, Cathy

Get full text

Real world evidence (RWE) – a disruptive innovation or the quiet evolution of medical evidence generation? by Khosla, Sajan, White, Robert, Medina, Jesús, Ouwens, Mario, Emmas, Cathy, Koder, Tim, Male, Gary, Leonard, Sandra

Get full text

Systematic review comparing meropenem with imipenem plus cilastatin in the treatment of severe infections by Edwards, Steven J., Emmas, Cathy E., Campbell, Helen E.

Get full text

Scaling PatientsLikeMe via a "Generalized Platform" for Members with Chronic Illness: Web-Based Survey Study of Benefits Arising by Wicks, Paul, Mack Thorley, Eileen, Simacek, Kristina, Curran, Christopher, Emmas, Cathy

Get full text

Characteristics, Symptom Severity, and Experiences of Patients Reporting Chronic Kidney Disease in the PatientsLikeMe Online Health Community: Retrospective and Qualitative Study by James, Glen, Nyman, Elisabeth, Fitz-Randolph, Marcy, Niklasson, Anna, Hedman, Katarina, Hedberg, Jonatan, Wittbrodt, Eric T, Medin, Jennie, Moreno Quinn, Carol, Allum, Alaster M, Emmas, Cathy

Get full text

Co-administration of statins with cytochrome P450 3A4 inhibitors in a UK primary care population by Bakhai, Ameet, Rigney, Una, Hollis, Samuel, Emmas, Cathy

Get full text

Annual cost of managing bipolar disorder to the UK healthcare system by Young, Allan H, Rigney, Una, Shaw, Samuel, Emmas, Cathy, Thompson, Jill M

Get full text

Clopidogrel discontinuation after acute coronary syndromes: frequency, predictors and associations with death and myocardial infarction-a hospital registry-primary care linked coho... by Boggon, Rachael, van Staa, Tjeerd P., Timmis, Adam, Hemingway, Harry, Ray, Kausik K., Begg, Alan, Emmas, Cathy, Fox, Keith A.A.

Get full text

Glycated Hemoglobin, Body Weight and Blood Pressure in Type 2 Diabetes Patients Initiating Dapagliflozin Treatment in Primary Care: A Retrospective Study by Wilding, John, Bailey, Clifford, Rigney, Una, Blak, Betina, Beekman, Wendy, Emmas, Cathy

Get full text

Using big data from health records from four countries to evaluate chronic disease outcomes: a study in 114 364 survivors of myocardial infarction by Rapsomaniki, Eleni, Thuresson, Marcus, Yang, Erru, Blin, Patrick, Hunt, Phillip, Chung, Sheng-Chia, Stogiannis, Dimitris, Pujades-Rodriguez, Mar, Timmis, Adam, Denaxas, Spiros C., Danchin, Nicolas, Stokes, Michael, Thomas-Delecourt, Florence, Emmas, Cathy, Hasvold, Pål, Jennings, Em, Johansson, Saga, Cohen, David J., Jernberg, Tomas, Moore, Nicholas, Janzon, Magnus, Hemingway, Harry

Get full text

DEVELOPMENT AND VALIDATION OF PROGNOSTIC MODELS FOR MYOCARDIAL INFARCTION, STROKE AND CARDIOVASCULAR DEATH AND HOSPITALISED BLEEDING IN STABLE MYOCARDIAL INFARCTION SURVIVORS by Pasea, Laura, Chung, Sheng-Chia, Rodriguez, Mar Pujades, Jennings, Em, Emmas, Cathy, Westergaard, Mogens, Johansson, Saga, Hemingway, Harry

Get full text

Anticoagulation in patients with non-valvular atrial fibrillation: an evaluation of stability and early factors that predict longer-term stability on warfarin in a large UK populat... by Currie, Craig J., McEwan, Phil, Emmas, Cathy, Morgan, Christopher Ll, Peters, John R.

Get full text

Analysis of protein-coding genetic variation in 60,706 humans by Lek, Monkol, Karczewski, Konrad J., Minikel, Eric V., Samocha, Kaitlin E., Banks, Eric, Fennell, Timothy, O’Donnell-Luria, Anne H., Ware, James S., Hill, Andrew J., Cummings, Beryl B., Tukiainen, Taru, Birnbaum, Daniel P., Kosmicki, Jack A., Duncan, Laramie E., Estrada, Karol, Zhao, Fengmei, Zou, James, Pierce-Hoffman, Emma, Berghout, Joanne, Cooper, David N., Deflaux, Nicole, DePristo, Mark, Do, Ron, Flannick, Jason, Fromer, Menachem, Gauthier, Laura, Goldstein, Jackie, Gupta, Namrata, Howrigan, Daniel, Kiezun, Adam, Kurki, Mitja I., Moonshine, Ami Levy, Natarajan, Pradeep, Orozco, Lorena, Peloso, Gina M., Poplin, Ryan, Rivas, Manuel A., Ruano-Rubio, Valentin, Rose, Samuel A., Ruderfer, Douglas M., Shakir, Khalid, Stenson, Peter D., Stevens, Christine, Thomas, Brett P., Tiao, Grace, Tusie-Luna, Maria T., Weisburd, Ben, Won, Hong-Hee, Yu, Dongmei, Altshuler, David M., Ardissino, Diego, Boehnke, Michael, Danesh, John, Donnelly, Stacey, Elosua, Roberto, Florez, Jose C., Gabriel, Stacey B., Getz, Gad, Glatt, Stephen J., Hultman, Christina M., Kathiresan, Sekar, Laakso, Markku, McCarroll, Steven, McCarthy, Mark I., McGovern, Dermot, McPherson, Ruth, Neale, Benjamin M., Palotie, Aarno, Purcell, Shaun M., Saleheen, Danish, Scharf, Jeremiah M., Sklar, Pamela, Sullivan, Patrick F., Tuomilehto, Jaakko, Tsuang, Ming T., Watkins, Hugh C., Wilson, James G., Daly, Mark J., MacArthur, Daniel G.

Get full text

UniProt: the Universal Protein Knowledgebase in 2023 by Bateman, Alex, Martin, Maria-Jesus, Orchard, Sandra, Magrane, Michele, Ahmad, Shadab, Alpi, Emanuele, Bowler-Barnett, Emily H, Britto, Ramona, Bye-A-Jee, Hema, Cukura, Austra, Denny, Paul, Dogan, Tunca, Ebenezer, ThankGod, Fan, Jun, Garmiri, Penelope, da Costa Gonzales, Leonardo Jose, Hatton-Ellis, Emma, Hussein, Abdulrahman, Ignatchenko, Alexandr, Insana, Giuseppe, Ishtiaq, Rizwan, Joshi, Vishal, Jyothi, Dushyanth, Kandasaamy, Swaathi, Lock, Antonia, Luciani, Aurelien, Lugaric, Marija, Luo, Jie, Lussi, Yvonne, MacDougall, Alistair, Madeira, Fabio, Mahmoudy, Mahdi, Mishra, Alok, Moulang, Katie, Nightingale, Andrew, Pundir, Sangya, Qi, Guoying, Raj, Shriya, Raposo, Pedro, Rice, Daniel L, Saidi, Rabie, Santos, Rafael, Speretta, Elena, Stephenson, James, Totoo, Prabhat, Turner, Edward, Tyagi, Nidhi, Vasudev, Preethi, Warner, Kate, Watkins, Xavier, Zaru, Rossana, Zellner, Hermann, Bridge, Alan J, Aimo, Lucila, Argoud-Puy, Ghislaine, Auchincloss, Andrea H, Axelsen, Kristian B, Bansal, Parit, Baratin, Delphine, Batista Neto, Teresa M, Blatter, Marie-Claude, Bolleman, Jerven T, Boutet, Emmanuel, Breuza, Lionel, Gil, Blanca Cabrera, Casals-Casas, Cristina, Echioukh, Kamal Chikh, Coudert, Elisabeth, Cuche, Beatrice, de Castro, Edouard, Estreicher, Anne, Famiglietti, Maria L, Feuermann, Marc, Gasteiger, Elisabeth, Gaudet, Pascale, Gehant, Sebastien, Gerritsen, Vivienne, Gos, Arnaud, Gruaz, Nadine, Hulo, Chantal, Hyka-Nouspikel, Nevila, Jungo, Florence, Kerhornou, Arnaud, Le Mercier, Philippe, Lieberherr, Damien, Masson, Patrick, Morgat, Anne, Muthukrishnan, Venkatesh, Paesano, Salvo, Pedruzzi, Ivo, Pilbout, Sandrine, Pourcel, Lucille, Poux, Sylvain, Pozzato, Monica, Pruess, Manuela, Redaschi, Nicole, Rivoire, Catherine, Sigrist, Christian J A, Sonesson, Karin, Sundaram, Shyamala

Get full text

UniProt: the universal protein knowledgebase in 2021 by Bateman, Alex, Martin, Maria-Jesus, Orchard, Sandra, Magrane, Michele, Agivetova, Rahat, Ahmad, Shadab, Alpi, Emanuele, Bowler-Barnett, Emily H, Britto, Ramona, Bursteinas, Borisas, Bye-A-Jee, Hema, Coetzee, Ray, Cukura, Austra, Da Silva, Alan, Denny, Paul, Dogan, Tunca, Ebenezer, ThankGod, Fan, Jun, Castro, Leyla Garcia, Garmiri, Penelope, Georghiou, George, Gonzales, Leonardo, Hatton-Ellis, Emma, Hussein, Abdulrahman, Ignatchenko, Alexandr, Insana, Giuseppe, Ishtiaq, Rizwan, Jokinen, Petteri, Joshi, Vishal, Jyothi, Dushyanth, Lock, Antonia, Lopez, Rodrigo, Luciani, Aurelien, Luo, Jie, Lussi, Yvonne, MacDougall, Alistair, Madeira, Fabio, Mahmoudy, Mahdi, Menchi, Manuela, Mishra, Alok, Moulang, Katie, Nightingale, Andrew, Oliveira, Carla Susana, Pundir, Sangya, Qi, Guoying, Raj, Shriya, Rice, Daniel, Lopez, Milagros Rodriguez, Saidi, Rabie, Sampson, Joseph, Sawford, Tony, Speretta, Elena, Turner, Edward, Tyagi, Nidhi, Vasudev, Preethi, Volynkin, Vladimir, Warner, Kate, Watkins, Xavier, Zaru, Rossana, Zellner, Hermann, Bridge, Alan, Poux, Sylvain, Redaschi, Nicole, Aimo, Lucila, Argoud-Puy, Ghislaine, Auchincloss, Andrea, Axelsen, Kristian, Bansal, Parit, Baratin, Delphine, Blatter, Marie-Claude, Bolleman, Jerven, Boutet, Emmanuel, Breuza, Lionel, Casals-Casas, Cristina, de Castro, Edouard, Echioukh, Kamal Chikh, Coudert, Elisabeth, Cuche, Beatrice, Doche, Mikael, Dornevil, Dolnide, Estreicher, Anne, Famiglietti, Maria Livia, Feuermann, Marc, Gasteiger, Elisabeth, Gehant, Sebastien, Gerritsen, Vivienne, Gos, Arnaud, Gruaz-Gumowski, Nadine, Hinz, Ursula, Hulo, Chantal, Hyka-Nouspikel, Nevila, Jungo, Florence, Keller, Guillaume, Kerhornou, Arnaud, Lara, Vicente, Le Mercier, Philippe, Lieberherr, Damien, Lombardot, Thierry, Martin, Xavier, Masson, Patrick

Request full text

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial by Aley, Parvinder K, Clutterbuck, Elizabeth A, Dold, Christina, Heath, Paul, Makinson, Rebecca, Pollock, Katrina M, Ramasamy, Maheshi, Robinson, Hannah, Douglas, Alexander D, Lambe, Teresa, Aboagye, Jeremy, Allen, Elizabeth, Anslow, Rachel, Baker, Philip, Bates, Louise, Batten, Alexander, Berry, Lisa, Beveridge, Amy, Bingham, Tracey, Brunt, Emily, Burbage, Jamie, Carroll, Miles W., Coombes, Naomi S., Cooper, Rachel, Crocker, Wendy E.M., Di Maso, Claudio, Dong, Tao, Douglas, Naomi, Downing, Charlotte, Elias, Sean C., Emary, Katherine R.W., Fletcher, Clare, Ford, Karen J., Fox, Polly, Frater, John, Galiza, Eva, Godwin, Kerry, Gorini, Giacomo, Goulston, Lyndsey, Gracie, Lara, Halwe, Sandro, Hamilton, Elizabeth, Hamlyn, Joseph, Harding, Irasha, Head, Ian, Hodgson, Susanne H.C., Howell, Nicola, Isitt, Catherine, Kailath, Reshma, Karampatsas, Konstantinos, Kerridge, Simon, Khan, Uzma, Kingham-Page, Lucy, Knott, Daniel, Koleva, Stanislava, Kupke, Alexandra, Lawrie, Alison M., Lee, Arlene, Lees, Emily A, Lias, Amelia M., Linder, Aline, Lopez Ramon, Raquel, Marlow, Emma, Marshall, Julia L., Meddaugh, Gretchen, Moore, Maria, Moran, Edward, Morris, Susan Jane, Morshead, Gertraud, Muller, Jilly, Munro, Alasdair, Noé, Andrés, O'Brien, Katie, O'Connor, Daniel, Oguti, Blanché, Oliver, Jennifer L., Osborn, Mairead, Pacurar, Mihaela, Pearce, Jennifer, Pfafferott, Katja, Poulton, Ian, Riddell, Amy, Sajjad, Sara, Sanders, Helen, Sanders, Katherine, Selby, Beatrice, Shelton, Holly, Song, Rinn, Stefanova, Elena, Tait, Moira, Talbot, Helen, Themistocleous, Yrene, Thomas, Merin, Towner, James, Turkentine, Kate, Turner, Sally, Veighey, Kristin, Vichos, Iason, Worth, Andrew T., Yau, Yasmine

Request full text

Prediction of Late Death or Disability at Age 5 Years Using a Count of 3 Neonatal Morbidities in Very Low Birth Weight Infants by Schmidt, Barbara, MD, Roberts, Robin S., MSc, Davis, Peter G., MD, Doyle, Lex W., MD, Asztalos, Elizabeth V., MD, Opie, Gillian, MD, Bairam, Aida, PhD, Solimano, Alfonso, MD, Arnon, Shmuel, MD, Sauve, Reginald S., MD

Get full text

Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity by Schmidt, Barbara, Anderson, Peter J, Doyle, Lex W, Dewey, Deborah, Grunau, Ruth E, Asztalos, Elizabeth V, Davis, Peter G, Tin, Win, Moddemann, Diane, Solimano, Alfonso, Ohlsson, Arne, Barrington, Keith J, Roberts, Robin S, Caffeine for Apnea of Prematurity (CAP) Trial Investigators, for the

Get full text